T1502 |
Vildagliptin
|
274901-16-5
|
98%
|
|
Vildagliptin (LAF237) is a cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Vildagliptin's cy...
|
T5679 |
(E)-Ferulic acid
|
537-98-4
|
98%
|
|
(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of ...
|
T5364 |
TBHQ
|
1948-33-0
|
98%
|
|
TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.
|
T4066 |
FIN56
|
1083162-61-1
|
97.86%
|
|
FIN56 is a specific inducer of ferroptosis.
|
T16540 |
Piperazine Erastin
|
1538593-71-3
|
97.74%
|
|
Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.
|
T2858 |
Baicalein
|
491-67-8
|
97.25%
|
|
Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor.
|
T6947 |
Piperlongumine
|
20069-09-4
|
97.21%
|
|
Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L. It selectively kills cancer cells and strengthens the level of reactive oxygen species (RO...
|
T8375 |
ML-210
|
1360705-96-9
|
97%
|
|
ML-210 (CID 49766530) is a selective RAS and covalent glutathione peroxidase 4 (GPX4) inhibitor(GPX4, EC50 : 30 nM), with anti-cancer activity
|
T0392 |
Artemisinin
|
63968-64-9
|
97%
|
|
Artemisinin (Qinghaosu) is an ancient Chinese herbal therapy for malarial fevers which has been recently found to have potent activity against many forms of mala...
|
T6243 |
U-73122
|
112648-68-7
|
96.73%
|
|
U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.
|
T2870 |
Matrine
|
519-02-8
|
100%
|
|
Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.
|
T0935 |
Butylated hydroxytoluene
|
128-37-0
|
100%
|
|
Butylated hydroxytoluene (BHT FCC/NF) is an organic chemical composed of 4-methylphenol modified with tert-butyl groups at positions 2 and 6. Butylated hydroxyto...
|
T1847 |
Necrostatin-1
|
4311-88-0
|
100%
|
|
Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity. Necrostatin-1 inhibits TNF-α-induced necrotic apoptosis. Necrostatin...
|
T0875 |
Acetylcysteine
|
616-91-1
|
100%
|
|
Acetylcysteine (NAC) is an N-acetyl derivative of cysteine, a ROS inhibitor and mucolytic agent. Acetylcysteine induces apoptosis, can be used to reduce mucus th...
|
T0214L |
Pioglitazone hydrochloride
|
112529-15-4
|
100%
|
|
Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic ac...
|
T6954 |
PRIMA-1
|
5608-24-2
|
|
|
PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.
|
T0326 |
DL-Glutamine
|
6899-04-3
|
|
|
DL-Glutamine (2-amino-4-carbamoylbutanoic acid), a non-essential amino acid, exists abundantly throughout the body and is participated in many metabolic processe...
|
T20819 |
Ammonium iron(III) citrate
|
1185-57-5
|
|
|
Ammonium iron(III) citrate (Ferric ammonium citrate) is a physiological form of non-ferritin-bound iron that causes intracellular iron overload leading to cellul...
|
T77762 |
ROS-generating agent 1
|
2369030-41-9
|
98%
|
|
Ros-generating agent 1 has anticancer activity and generates ROS by covalently modifying Sec-498 residues of TrxR. ROS-generating agent 1 reduces intracellular T...
|
T77765 |
FSEN1
|
862808-01-3
|
98%
|
|
FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM. FSEN1 induces iron death in cancer cells by inhibiting FSP1. F...
|