GABA Receptor

The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors.

Cat. No.	Product name	CAS No.	Purity
T5734	(+)-BORNEOL	464-43-7	99.6%
T5734	(+)-BORNEOL (d-Borneol) is a natural bicyclic monoterpene used for analgesia and anesthesia in traditional Chinese medicine; enhances GABA receptor activity with...
T3698	Alpha-Asarone	2883-98-9	99.59%
T3698	alpha-Asarone (trans-Asarone) is a psychoactive compound with antidepressant-like activity in mice.
TQ0119	Cirsimaritin	6601-62-3	99.59%
TQ0119	Cirsimaritin exhibits antibacterial, anti-inflammation, anti-tumor, antioxidant properties and renal protection. Cirsimaritin binds weakly to the benzodiazepine ...
T16811	RWJ-51204	205701-85-5	99.57%
T16811	RWJ-51204 is a selective adenosine A2A receptor antagonist and a partial agonist of GABA(A) receptor (IC50: 0.2-2 nM). It has neuroprotective and movement-improv...
T36520	COR659	544450-68-2	99.56%
T36520	COR659 is a GABAB positive allosteric modulator (PAM) . COR659 suppresses alcohol and chocolate self-administration in rats[1]. COR659 apparently exerts its effe...
T12207	NEO 376	496921-73-4	99.56%
T12207	NEO 376 (SPI-376) is a selective 5-HT1 receptor, GABA receptor and dopamine receptor modulator, showing anti-psychotic actively.
TQ0040	ONO-8590580	1802661-73-9	99.54%
TQ0040	ONO-8590580 (CS-2894) is a negative allosteric modulator of GABAA α5.
T4440	Saclofen	125464-42-8	99.54%
T4440	Saclofen is a sulfonic analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that acts as a competitive antagonist of the GABAB receptor (IC50: 7....
T23481	U 89843A	157013-32-6	99.53%
T23481	Positive allosteric modulator of GABAA receptors
T2S1814	P-Hydroxybenzaldehyde	123-08-0	99.53%
T2S1814	1. p-Hydroxybenzaldehyde (p-Oxybenzaldehyde) shows an inhibitory effect on the GABA transaminase to contribute to an antiepileptic and anticonvulsive activity, a...
TQ0023	Lorediplon	917393-39-6	99.53%
TQ0023	Lorediplon is a novel hypnotic drug acting as a GABAA receptor modulator, differentially active at the α1-subunit, associated with promoting sleep.
TN1023	Miltirone	27210-57-7	99.51%
TN1023	Miltirone is a CYPs inhibitor, it has been characterized as a low-affinity ligand for central benzodiazepine receptors.
T26600	Alpidem	82626-01-5	99.49%
T26600	Alpidem (Ananxyl) is an anxiolytic drug from the imidazopyridine family. Alpidem does not produce sedative effects at normal doses, and is instead used specifica...
T7064	Valproic Acid	99-66-1	99.49%
T7064	Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that inhibits HDAC1 activity, induces HDAC2 degradation, and is orally active. Valproic Acid can be u...
T2749	Ginkgolide A	15291-75-5	99.48%
T2749	Ginkgolide A (BN-52020) is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide var...
T0128	Vigabatrin	60643-86-9	99.47%
T0128	Vigabatrin (Sabril), an analogue of gamma-aminobutyric acid, is an irreversible inhibitor of 4-aminobutyrate Transaminase responsible for the catabolism of γ-ami...
TN1325	(2S)-6-Prenylnaringenin	68236-13-5	99.47%
TN1325	(2S)-6-Prenylnaringenin (6-Prenylnaringenin) is an isomer of the potent phytoestrogen, 8-prenylnaringenin. (2S)-6-Prenylnaringenin is the most potent compound in...
T6507	Gabapentin hydrochloride	60142-95-2	99.46%
T6507	Gabapentin hydrochloride (Neurontin HCl) is a GABA analogue, used to treat seizures and neuropathic pain.
T14571	Bifenazate	149877-41-8	99.44%
T14571	Bifenazate is a positive allosteric modulator of GABA receptor. Bifenazate is an acaricide that controls 100% of mites at a concentration of 25 ppm.
T6355	(R)-baclofen	69308-37-8	99.43%
T6355	(R)-baclofen (STX209), a derivative of gamma-aminobutyric acid, is commonly utilized for the treatment of spasticity.