Home Tools
Log in
Cart

GABA Receptor

The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T4688 Pipequaline hydrochloride 80221-58-5 99.43%
Pipequaline hydrochloride
Pipequaline hydrochloride (PK-8165 hydrochloride) is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. It ...
T11684 Isoguvacine hydrochloride 68547-97-7 99.41%
Isoguvacine hydrochloride
Isoguvacine hydrochloride (1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride) is a GABA receptor agonist. Isoguvacine hydrochloride binds to rat synapti...
T0702 Gabapentin 60142-96-3 99.39%
Gabapentin
Gabapentin (Neurontin) is an Anti-epileptic Agent. The physiologic effect of gabapentin is by means of Decreased Central Nervous System Disorganized Electrical A...
T34146 Propanidid 1421-14-3 99.39%
Propanidid
Propanidid (Sombrevin) is a gamma-aminobutyric acid type A receptor (GABAA) agonist and a fast-acting intravenous anesthetic that lowers arterial blood pressure....
T20242 Chlorothymol 89-68-9 99.37%
Chlorothymol
Chlorothymol (AI3-00120) is a disinfectant used in oral.
T15775 Lotilaner 1369852-71-0 99.32%
Lotilaner
Lotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors (IC50 of 23.84 nM for Drosophila melanogaster GABA rec...
T8887 2'MeO6MF 89112-85-6 99.26%
2'MeO6MF
2'MeO6MF is a brain-penetrant positive allosteric modulator at α2β1γ2L and all α1-containing GABAA receptors.It offers neuroprotection and improved functional re...
T13690 Etifoxine hydrochloride 56776-32-0 99.25%
Etifoxine hydrochloride
Etifoxine hydrochloride (HOE 36-801 hydrochloride) is an anxiolytic and anticonvulsant drug. Unlike benzodiazepines, Etifoxine hydrochloride appears to produce i...
T26891 BPDBA 312281-74-6 99.24%
BPDBA
BPDBA is an effective, selective, and non-competitive inhibitor of the betaine/GABA transporter (BGT-1), displaying inhibitory activity against human BGT-1 and m...
T2407 Tiagabine 115103-54-3 99.24%
Tiagabine
Tiagabine (NO050328) is an Anti-epileptic Agent. The physiologic effect of tiagabine is by means of Decreased Central Nervous System Disorganized Electrical Acti...
T2983 3,4,5-Trimethoxycinnamic acid 90-50-6 99.19%
3,4,5-Trimethoxycinnamic acid
3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at the GA...
T4363 CGP52432 139667-74-6 99.16%
CGP52432
CGP52432 is a very potent antagonist of GABAB receptors (IC50 = 85 nM).
T3S2100 (-)-Securinine 5610-40-2 99.12%
(-)-Securinine
(-)-Securinine (Securinine) is plant-derived alkaloid and also a GABAA receptor antagonist.
T77568 6,7-dimethylisatin 20205-43-0 99.09%
6,7-dimethylisatin
6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.
T23470 Tracazolate hydrochloride 1135210-68-2 99.07%
Tracazolate hydrochloride
Tracazolate hydrochloride (Tracazolate (hydrochloride)) is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity. Tracazolate hydrochlori...
T17144 TPA 023 252977-51-8 99.06%
TPA 023
TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).
T0627 β-Alanine 107-95-9 99%
β-Alanine
β-Alanine (3-Aminopropanoic acid) is a naturally occurring beta amino acid formed in vivo by the degradation of dihydrouracil and carnosine. It acts as a neurotr...
T0883 Tramiprosate 3687-18-1 99%
Tramiprosate
Tramiprosate (Alzhemed) is an orally active, blood-brain-barrier-crossing, naturally occurring amino acid found in a variety of red seaweeds that binds soluble A...
T1602 Valproic acid sodium salt 1069-66-5 99%
Valproic acid sodium salt
Valproic acid sodium salt (Sodium Valproate) is the sodium salt form of valproic acid with anti-epileptic activity. Valproic acid sodium salt is converted into i...
T2775 Baicalin 21967-41-9 98.96%
Baicalin
Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV proper...
Pipequaline hydrochloride
T4688
Pipequaline hydrochloride (PK-8165 hydrochloride) is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. It ...
Isoguvacine hydrochloride
T11684
Isoguvacine hydrochloride (1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride) is a GABA receptor agonist. Isoguvacine hydrochloride binds to rat synapti...
Gabapentin
T0702
Gabapentin (Neurontin) is an Anti-epileptic Agent. The physiologic effect of gabapentin is by means of Decreased Central Nervous System Disorganized Electrical A...
Propanidid
T34146
Propanidid (Sombrevin) is a gamma-aminobutyric acid type A receptor (GABAA) agonist and a fast-acting intravenous anesthetic that lowers arterial blood pressure....
Chlorothymol
T20242
Chlorothymol (AI3-00120) is a disinfectant used in oral.
Lotilaner
T15775
Lotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors (IC50 of 23.84 nM for Drosophila melanogaster GABA rec...
2'MeO6MF
T8887
2'MeO6MF is a brain-penetrant positive allosteric modulator at α2β1γ2L and all α1-containing GABAA receptors.It offers neuroprotection and improved functional re...
Etifoxine hydrochloride
T13690
Etifoxine hydrochloride (HOE 36-801 hydrochloride) is an anxiolytic and anticonvulsant drug. Unlike benzodiazepines, Etifoxine hydrochloride appears to produce i...
BPDBA
T26891
BPDBA is an effective, selective, and non-competitive inhibitor of the betaine/GABA transporter (BGT-1), displaying inhibitory activity against human BGT-1 and m...
Tiagabine
T2407
Tiagabine (NO050328) is an Anti-epileptic Agent. The physiologic effect of tiagabine is by means of Decreased Central Nervous System Disorganized Electrical Acti...
3,4,5-Trimethoxycinnamic acid
T2983
3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at the GA...
CGP52432
T4363
CGP52432 is a very potent antagonist of GABAB receptors (IC50 = 85 nM).
(-)-Securinine
T3S2100
(-)-Securinine (Securinine) is plant-derived alkaloid and also a GABAA receptor antagonist.
6,7-dimethylisatin
T77568
6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.
Tracazolate hydrochloride
T23470
Tracazolate hydrochloride (Tracazolate (hydrochloride)) is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity. Tracazolate hydrochlori...
TPA 023
T17144
TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).
β-Alanine
T0627
β-Alanine (3-Aminopropanoic acid) is a naturally occurring beta amino acid formed in vivo by the degradation of dihydrouracil and carnosine. It acts as a neurotr...
Tramiprosate
T0883
Tramiprosate (Alzhemed) is an orally active, blood-brain-barrier-crossing, naturally occurring amino acid found in a variety of red seaweeds that binds soluble A...
Valproic acid sodium salt
T1602
Valproic acid sodium salt (Sodium Valproate) is the sodium salt form of valproic acid with anti-epileptic activity. Valproic acid sodium salt is converted into i...
Baicalin
T2775
Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV proper...
1 2 3 4 5 6 7 8 9 10
TargetMol