T10618 |
Broflanilide
|
1207727-04-5
|
98.95%
|
|
Broflanilide is metabolized to desmethyl-broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin GABA receptor and inhibits S. litura RDL ...
|
T11061 |
DMCM hydrochloride
|
1215833-62-7
|
98.95%
|
|
DMCM hydrochloride is a non-selective fully inverse agonist of benzodiazepine. DMCM showed significant differences in human recombinant GABAA αxβ3γ2 receptor sub...
|
T38205 |
3-Aminopropylphosphonic Acid
|
13138-33-5
|
98.9%
|
|
3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding as...
|
T23339 |
SCS
|
3232-36-8
|
98.89%
|
|
SCS is a GABAA receptor antagonist.
|
T11277 |
FG 7142
|
78538-74-6
|
98.81%
|
|
FG 7142 (LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 can increase tyrosine hydroxylati...
|
T22301 |
L-838417 D9
|
1213669-91-0
|
98.81%
|
|
L-838417 D9 (C-21191) is a novel deuterated subtype-selective GABAA positive allosteric modulator, acting as a partial agonist at α2, α3 and α5 subtypes[1].
|
T23104 |
Ocinaplon
|
96604-21-6
|
98.78%
|
|
Ocinaplon (DOV 273547) is a GABAA receptors modulator.
|
T28900 |
T-2000
|
97846-21-4
|
98.75%
|
|
T-2000 (DMMDPB) is a GABA receptor agonist that can be used to study myoclonus and essential tremor.
|
TN1217 |
2'-O-Methylisoliquiritigenin
|
51828-10-5
|
98.75%
|
|
2'-O-Methylisoliquiritigenin, a compound synthesized by enzymes specifically induced in NR.2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-re...
|
T12930 |
SKF89976A hydrochloride
|
85375-15-1
|
98.72%
|
|
SKF89976A hydrochloride (d,l-SKF89976A hydrochloride) is a selective inhibitor GABA transporter such as GAT-1 (IC50s = 0.28 μM), GAT-2 (IC50s = 137.34 μM) and GA...
|
T15212 |
Emamectin Benzoate
|
155569-91-8
|
98.68%
|
|
Emamectin Benzoate (MK-244), by binding gamma-aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropods,...
|
T3318 |
Wogonoside
|
51059-44-0
|
98.66%
|
|
Wogonoside (Wogonin 7-O-glucuronide) acts as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor.
|
T11822 |
LAU159
|
2055050-87-6
|
98.65%
|
|
LAU159 is a functionally selective positive α1β3 GABA(A) receptor modulator(EC50 : 2.2 μM).
|
T77796 |
DL-Borneol
|
507-70-0
|
98.61%
|
|
DL-Borneol ((endo)-Borneol) is a small molecule extracted from traditional Chinese medicine (TCM). It is an orally bioadjuvant that improves drug delivery to the...
|
T27310 |
Fengabine
|
80018-06-0
|
98.54%
|
|
Fengabine (SL-79229) is a GABA receptor agonist with antidepressant activity and is used to treat depression.
|
T28887 |
Suriclone
|
53813-83-5
|
98.52%
|
|
Suriclone (RP 31264) is a selective cyclic pyrrolidone analog with sedative and anxiolytic activity, but not significant sedative effects.Suriclone shows its eff...
|
T3782 |
Jujuboside A
|
55466-04-1
|
98.49%
|
|
Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, having neurophysiological inhibitory effects, used as a potential therapeutic agent for the tr...
|
T1860 |
Imepitoin
|
188116-07-6
|
98.45%
|
|
Imepitoin (AWD 131-138) is a new low-affinity partial benzodiazepine receptor agonist. It shows potent anticonvulsant and anxiolytic properties in rodent models....
|
T14983 |
Clomethiazole
|
533-45-9
|
98.43%
|
|
Clomethiazole (Distraneurin) is an orally active GABAA agonist and it is an anticonvulsant agent. It also has the potential for treating convulsive status epilep...
|
TQ0151 |
L-655708
|
130477-52-0
|
98.41%
|
|
L-655708 is a selective and highly potent GABAA receptor reverse agonist with a Ki value of 0.45 nM.
|