GABA Receptor

The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors.

Cat. No.	Product name	CAS No.	Purity
TQ0151	L-655708	130477-52-0	98.41%
TQ0151	L-655708 is a selective and highly potent GABAA receptor reverse agonist with a Ki value of 0.45 nM.
T8193	α-Thujone	546-80-5	98.41%
T8193	α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.
T8971	Imidazenil	151271-08-8	98.4%
T8971	Imidazenil is an modulator of GABA-A that blocks the sedative effects without lowering the convulsion threshold.
T7793	6-(4-Methoxyphenyl)-3-pyridazinamine	4776-87-8	98.39%
T7793	6-(4-Methoxyphenyl)-3-pyridazinamine is a GABAA receptor antagonist
T8162	Cannabidivarin	24274-48-4	98.3%
T8162	Cannabidivarin (GWP42006) is a potent inhibitor against gamma 2 subunit of GABAA receptors. it may serve as a novel drug with definite control over childhood abs...
TN6773	Acetoxyvalerensre	81397-67-3	98.22%
TN6773	Acetoxyvalerensre (acetylvalerenolic acid) (acetylvalerenolic acid) is a derivative of valerenic acid, which is a a GABAA receptor modulator.
T7622	Gabazine	104104-50-9	98.2%
T7622	Gabazine (SR95531) is an antagonist of GABAA receptors (Ki : 74-150 nM)
T3S2259	Methyl eugenol	93-15-2	98.16%
T3S2259	1. Methyl eugenol (4-allylveratrole) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents, in view...
T28303	Pazinaclone	103255-66-9	98.12%
T28303	Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity.
T0958	Penicillin G sodium salt	69-57-8	98.11%
T0958	Penicillin G sodium(Benzylpenicillin sodium) salt is a penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a var...
T16535	Picrotoxinin	17617-45-7	98.07%
T16535	Picrotoxinin is a blocker of chloride channel and a noncompetitive antagonist of GABAA with an IC50 of 1.15 μM for α1β2γ2L GABAA. Picrotoxinin shows convulsant p...
T22348	Isonipecotic acid	498-94-2	98.02%
T22348	Isonipecotic acid (4-Piperidinecarboxylic acid) is a heterocyclic compound. Isonipecotic acid mainly characterized as a GABAA receptor partial agonist.
TN1202	(-)-α-Pinene	7785-26-4	98.02%
TN1202	(-)-α-Pinene ((1S)-(-)-Alpha-Pinene) enhances the quantity of NREMS without affecting the intensity of NREMS by prolonging GABAergic synaptic transmission, actin...
T3403	Glabridin	59870-68-7	98.01%
T3403	Glabridin (KB-289522) may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS und...
T23466	TP003	628690-75-5	98%
T23466	TP003 is a novel non-selective GABAA receptor benzodiazepine site agonist with affinity for α1β2gam2, α2β3gam2, α3β3gam2, α5β2gam2, EC50 of 20.3, 10.6, 3.24, 5.6...
T7136	AZD-6280	942436-93-3	98%
T7136	AZD6280 is a novel, subtype-selective GABAAα2/3 receptor positive modulators, used for treatment of generalized anxiety disorder.
T4590	(+)-Kavain	500-64-1	98%
T4590	(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.
T0675	Topiramate	97240-79-4	98%
T0675	Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associate...
T2196	Fipronil	120068-37-3	98%
T2196	Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is a broad-spectrum insecticide that disr...
T7165	Basmisanil	1159600-41-5	98%
T7165	Basmisanil (RG1662) is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for the tre...