T7595 |
L-DABA
|
1758-80-1
|
98%
|
|
L-DABA (L-2,4-Diaminobutyric acid) is an inhibitor of GABA transaminase (IC50 > 500 μM).
|
T5754 |
Kavain
|
3155-48-4
|
98%
|
|
Kavain, a compound extracted from the Kava plant, Piper methysticum, is found to be involved in TNF-α expression in human and mouse cells via regulation of trans...
|
TMS0418 |
Dihydroergotoxine mesylate
|
8067-24-1
|
98%
|
|
Dihydroergotoxine mesylate (Ergoloid mesylates) is mainly used to improve symptoms and physical symptoms of mental degeneration related to aging.
|
T27838 |
Lirequinil
|
143943-73-1
|
97.86%
|
|
Lirequinil (Ro 41-3696) is a small molecule GABAA receptor agonist used to study neurological disorders.
|
TN1432 |
Bacopasaponin C
|
178064-13-6
|
97.85%
|
|
Bacopasaponin C may have antioxidant activity, it also shows anti-leishmanial property.
|
T4522 |
SSD114 HCl
|
2319790-02-6
|
97.83%
|
|
SSD114 is a novel GABAB receptor positive allosteric modulator.
|
T5S1882 |
Songorine
|
509-24-0
|
97.34%
|
|
Songorine (Napellonine) shows favorable anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking...
|
T28159 |
Nerisopam
|
102771-12-0
|
97.27%
|
|
Nerisopam is an agonist of gamma-aminobutyric acid (GABA) receptor.
|
T23445 |
Anxiolytic/nonsedative agent-1
|
355022-97-8
|
97.05%
|
|
Anxiolytic/nonsedative agent-1 (TCS 1205) is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovin...
|
T16831 |
(S)-SNAP5114
|
157604-55-2
|
97%
|
|
(S)-SNAP5114 is a selective inhibitor of GABA transport with IC50s of 5 μM for hGAT-3 and 21 μM for rGAT-2. (S)-SNAP5114 has anticonvulsant properties.
|
T27186 |
Divaplon
|
90808-12-1
|
96.90%
|
|
Divaplon is a GABA receptor agonist (IC50: 0.056 µM) that displays non-sedating anxiolytic behavioral characteristics in a rat model of anxiety.
|
T24540 |
NO-711ME
|
127586-66-7
|
96.14%
|
|
NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor.
|
T11137 |
(E)-GABAB receptor antagonist 1
|
1611483-29-4
|
95.26%
|
|
(E)-GABAB receptor antagonist 1 is a trans-GABAB receptor antagonist 1. (E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) produ...
|
T0169 |
Nefiracetam
|
77191-36-7
|
100%
|
|
Nefiracetam (DM9384) are underway in Phase 2 trials. Nefiracetam, a GABAergic、 cholinergic、and monoaminergic neuronal system enhancer, is used for Ro 5-4864-indu...
|
TN3174 |
6-Methoxyflavanone
|
3034-04-6
|
100%
|
|
6-Methoxyflavanone (6-MeOF) is A positive allosteric modulator of the GABA response of human recombinant GABA A receptor, with antianxiety and anti-inflammatory ...
|
TN2268 |
Tetrahydromagnolol
|
20601-85-8
|
100%
|
|
Tetrahydromagnolol can activate cannabinoid (CB) receptors.
|
T2990 |
Phenibut
|
1078-21-3
|
100%
|
|
Phenibut (Aminophenylbutyric acid) is a central depressant and derivative of the naturally occurring inhibitory neurotransmitter γ-aminobutyric acid (GABA).
|
T4176 |
Rac-BHFF
|
123557-91-5
|
100%
|
|
rac-BHFF ((R,S)-BHFF) is potent and selective GABA B receptor positive allosteric modulator that increases the potency and efficacy of GABA ( > 15-fold and > 149...
|
T8568 |
Suritozole
|
110623-33-1
|
100%
|
|
Suritozole (MDL-26479) is a negative modulator at the gamma-aminobutyric acidA (GABAA) receptor
|
T27845 |
Losigamone
|
112856-44-7
|
100%
|
|
Losigamone (AO-33) is an agonist of GABA receptor and can be used in studies about the treatment of partial seizures.
|