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Cat No. | Product Name | Synonyms | Targets |
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TP1288 | Fertirelin | Others | |
Fertirelin, or fertirelin acetate, sold under the brand name Ovalyse, is a gonadotropin-releasing hormone agonist (GnRH agonist). | |||
T1494 | Alarelin Acetate | Alarelin | GNRH Receptor |
Alarelin Acetate is a synthetic GnRH agonist which can directly inhibit proliferation and DNA synthesis of rat GSMC through GnRH receptors. | |||
T27837 | Linzagolix | GNRH Receptor | |
Linzagolix is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist (GnRH antagonist) which is under development by Kissei Pharmaceutical and ObsEva for the treatment of uterine fibroids,... | |||
T5520 | Cetrorelix Acetate | Cetrorelix | GNRH Receptor |
Cetrorelix Acetate is gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM. | |||
T3630 | Relugolix | RVT-601,TAK-385 | GNRH Receptor |
Relugolix (RVT-601) is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with potential antineoplastic activity. Relugolix competitively bi... | |||
T11174 | (R)-Elagolix | NBI-56418 | GNRH Receptor |
(R)-Elagolix (NBI-56418) is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively. administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a do... | |||
T4102 | Goserelin acetate | Fertilan,ICI-118630 acetate,Zoladex | Apoptosis , GNRH Receptor |
Goserelin acetate (Fertilan) is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer. | |||
T5031 | Elagolix sodium | NBI-56418 sodium | GNRH Receptor |
Elagolix sodium (NBI-56418 sodium) is a GnRH receptor (GnRHR) antagonist ( IC50 and Ki of 0.25 and 3.7 nM, respectively). | |||
T10217L | Abarelix | R3827,PPI 149 | GNRH Receptor |
Abarelix (PPI 149) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, which is used for prostate cancer treatment. | |||
T5520L | Cetrorelix diacetate | NS-75A,SB-075 acetate,SB-075 diacetate,Cetrorelix acetate,NS-75A diacetate | GNRH Receptor |
Cetrorelix diacetate (NS-75A) is is a gonadotropin-releasing hormone antagonist. It works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of luteinizing hormone (LH) ... | |||
T21308 | Histrelin | Supprelin LA,Histrelin Acetate | Others |
Histrelin (Supprelin LA) acetate is a nonapeptide analog of gonadotropin-releasing hormone (GnRH) with added potency. It is considered a GnRH agonist. Histrelin is used in the treatment of hormone-sensitive cancers of th... | |||
T22025 | AG 045572 | P450 , GNRH Receptor | |
AG 045572 is a potent GnRH receptor antagonist that inhibits the GnRH receptor in humans and rats with Ki values of 6.0 nM and 3.8 nM, respectively.AG 045572 is metabolized by CYP3A and inhibits testosterone. | |||
TP2337 | Ganirelix Acetate | GNRH Receptor | |
Ganirelix Acetate is a gonadotropin-releasing hormone (GnRH) receptor antagonist | |||
TP1896L1 | Kisspeptin 234 acetate(1145998-81-7 free base) | GPR , Kisspeptin | |
Kisspeptin 234 acetate is a kisspeptin receptor antagonist. Kisspeptin 234 inhibits kisspeptin-10 stimulation of IP (IC50 = 7 nM) and release of GnRH. | |||
T10475 | BAY-784 | Others | |
BAY-784 is a gonadotropin-releasing hormone receptor (GnRH-R) antagonist (IC50s: 21 and 24 nM for human and rat GnRH-R). | |||
T23412 | T 98475 | Others | |
gonadotropin-releasing hormone (GnRH, LHRH) receptor antagonist,orally active | |||
T37003 | GnRH antagonist 2 | ||
GnRH antagonist 2 (formula I) is a potent GnRH receptor antagonist with valuable applications in endometriosis research[1]. | |||
TP1896 | Kisspeptin 234 | ||
Kisspeptin 234 is a kisspeptin receptor antagonist. Kisspeptin 234 inhibits kisspeptin-10 stimulation of IP (IC50 = 7 nM) and release of GnRH. | |||
T69383 | NBI-42902 | ||
NBI-42902 is a potent inhibitor of peptide radioligand binding to the human GnRH receptor (K(i) = 0.56 nm). Tritiated NBI-42902 binds with high affinity (K(d) = 0.19 nm) to a single class of binding sites and can be disp... | |||
T76350 | [D-Glp1,D-Phe2,D-Trp3,6]-LH-RH | ||
[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Glp1,D-Phe2,D-Trp3,6]-LH-RH acts as a GnRH receptor antagonist [1] . | |||
T76351 | [D-Ala6]-LH-RH | ||
[D-Ala6]-LH-RH, a Luteinizing-hormone-releasing hormone (LHRH) analogue, functions as a gonadotropin-releasing hormone (GnRH) receptor agonist [1]. | |||
T76348 | [D-Lys6]-LH-RH | ||
[D-Lys6]-LH-RH is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Lys6]-LH-RH acts as a GnRH receptor agonist [1] . | |||
T28795 | SKI2496 | SKI 2496,SKI-2496 | |
SKI2496 is a potent and orally bioavailableantagonist of Gonadotropin-Releasing Hormone Receptor (hGnRHR IC50 = 0.46 nM; max. LH inh. inh. (%, h)= 84%, 12h; LH inh. (24h) = 76%.). SKI2496 exhibits more selective antagoni... | |||
T70309 | Dicetrorelix pamoate | ||
Dicetrorelix pamoate is a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity. GnRH induces the production and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH)... | |||
TP1936 | RFRP-3(human) | RFRP 3 (human) | |
Agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). Homolog of gonadotropin-inhibitory hormone (GnIH); inhibits activity of gonadotropin-releasing hormone (GnRH) neurons. | |||
T76339 | Kisspeptin 13 | ||
Kisspeptin 13 is a GPR54 and GnRH receptor activator, an endogenous active isoform. Kisspeptin 13 enhances memory and can be used in Alzheimer's disease research [1] . | |||
T70775 | Zoptarelin doxorubicin | ||
Zoptarelin doxorubicin, also known as AEZS-108, is an LHRH agonist. Zoptarelin doxorubicin is a peptide agonist of the gonadotropin releasing hormone-1 receptor (GnRH-1R) that is conjugated to the anthracycline antibio... | |||
T76436 | [MePhe7]-Neurokinin B | ||
[MePhe7]-Neurokinin B is an neurokinin NK-3 receptor ( NK3R ) agonist with an IC 50 value of 3 nM. [MePhe7]-Neurokinin B is a potential regulator of pulsatile gonadotropin-releasing hormone (GnRH) secretion via activatio... | |||
T81485 | Phoenixin-14 TFA | PNX-14 TFA | |
Phoenixin-14 TFA (PNX-14) is a blood-brain barrier (BBB)-penetrable neuropeptide with anxiolytic, cardioprotective, and neuroprotective properties. It modulates pituitary gonadotrophin release by enhancing gonadotropin-r... | |||
T76047 | TAK-683 TFA | ||
TAK-683 TFA is a potent full KISS1 receptor (KISS1R) agonist ( IC 50 =170 pM) with improved metabolic stability. TAK-683 TFA is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC 50 values of ... | |||
T76048 | TAK-683 acetate | ||
TAK-683 acetate is a potent full KISS1 receptor (KISS1R) agonist ( IC 50 =170 pM) with improved metabolic stability. TAK-683 acetate is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC 50 va... | |||
T69492 | Ozarelix | ||
Ozarelix is a fourth generation GnRH antagonist, induces apoptosis in hormone refractory androgen receptor negative prostate cancer cells modulating expression and activity of death receptors. Mechanistically, LHRH antag... | |||
T35794 | Kisspeptin-54 (human) (trifluoroacetate salt) | ||
Kisspeptin-54 is a peptide ligand of the orphan G protein-coupled receptor GPR54 (Kis = 1.81 and 1.45 nM for rat and human receptors, respectively).1 It is a 54 amino acid peptide encoded by the metastasis suppressor gen... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00395 | FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differen... | |||
TMPK-00393 | FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differen... | |||
TMPY-02393 | Thimet Oligopeptidase/THOP1 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
THOP1, also known as Thimet oligopeptidase 1, Thimet oligopeptidase, EC 3.4.24.15, or EP24.15, is a zinc(II) endopeptidase implicated in the processing of numerous physiological peptides. As an intracellular enzyme, high... | |||
TMPY-04307 | GNRH2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
GNRH2 (Gonadotropin-Releasing Hormone 2) is a Protein Coding gene. This gene is a member of the gonadotropin-releasing hormone (GnRH) gene family. Proteins encoded by members of this gene family are proteolytically cleav... | |||
TMPH-01210 | DENR Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required... | |||
TMPH-01209 | DENND1A Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required... |