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Search Results for " gnrh-receptor "

Targets

33

Compounds

6

Recombinant Proteins

Cat No. Product Name Synonyms Targets
TP1288 Fertirelin Others
Fertirelin, or fertirelin acetate, sold under the brand name Ovalyse, is a gonadotropin-releasing hormone agonist (GnRH agonist).
T1494 Alarelin Acetate Alarelin GNRH Receptor
Alarelin Acetate is a synthetic GnRH agonist which can directly inhibit proliferation and DNA synthesis of rat GSMC through GnRH receptors.
T27837 Linzagolix GNRH Receptor
Linzagolix is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist (GnRH antagonist) which is under development by Kissei Pharmaceutical and ObsEva for the treatment of uterine fibroids,...
T5520 Cetrorelix Acetate Cetrorelix GNRH Receptor
Cetrorelix Acetate is gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM.
T3630 Relugolix RVT-601,TAK-385 GNRH Receptor
Relugolix (RVT-601) is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with potential antineoplastic activity. Relugolix competitively bi...
T11174 (R)-Elagolix NBI-56418 GNRH Receptor
(R)-Elagolix (NBI-56418) is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively. administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a do...
T4102 Goserelin acetate Fertilan,ICI-118630 acetate,Zoladex Apoptosis , GNRH Receptor
Goserelin acetate (Fertilan) is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer.
T5031 Elagolix sodium NBI-56418 sodium GNRH Receptor
Elagolix sodium (NBI-56418 sodium) is a GnRH receptor (GnRHR) antagonist ( IC50 and Ki of 0.25 and 3.7 nM, respectively).
T10217L Abarelix R3827,PPI 149 GNRH Receptor
Abarelix (PPI 149) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, which is used for prostate cancer treatment.
T5520L Cetrorelix diacetate NS-75A,SB-075 acetate,SB-075 diacetate,Cetrorelix acetate,NS-75A diacetate GNRH Receptor
Cetrorelix diacetate (NS-75A) is is a gonadotropin-releasing hormone antagonist. It works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of luteinizing hormone (LH) ...
T21308 Histrelin Supprelin LA,Histrelin Acetate Others
Histrelin (Supprelin LA) acetate is a nonapeptide analog of gonadotropin-releasing hormone (GnRH) with added potency. It is considered a GnRH agonist. Histrelin is used in the treatment of hormone-sensitive cancers of th...
T22025 AG 045572 P450 , GNRH Receptor
AG 045572 is a potent GnRH receptor antagonist that inhibits the GnRH receptor in humans and rats with Ki values of 6.0 nM and 3.8 nM, respectively.AG 045572 is metabolized by CYP3A and inhibits testosterone.
TP2337 Ganirelix Acetate GNRH Receptor
Ganirelix Acetate is a gonadotropin-releasing hormone (GnRH) receptor antagonist
TP1896L1 Kisspeptin 234 acetate(1145998-81-7 free base) GPR , Kisspeptin
Kisspeptin 234 acetate is a kisspeptin receptor antagonist. Kisspeptin 234 inhibits kisspeptin-10 stimulation of IP (IC50 = 7 nM) and release of GnRH.
T10475 BAY-784 Others
BAY-784 is a gonadotropin-releasing hormone receptor (GnRH-R) antagonist (IC50s: 21 and 24 nM for human and rat GnRH-R).
T23412 T 98475 Others
gonadotropin-releasing hormone (GnRH, LHRH) receptor antagonist,orally active
T37003 GnRH antagonist 2
GnRH antagonist 2 (formula I) is a potent GnRH receptor antagonist with valuable applications in endometriosis research[1].
TP1896 Kisspeptin 234
Kisspeptin 234 is a kisspeptin receptor antagonist. Kisspeptin 234 inhibits kisspeptin-10 stimulation of IP (IC50 = 7 nM) and release of GnRH.
T69383 NBI-42902
NBI-42902 is a potent inhibitor of peptide radioligand binding to the human GnRH receptor (K(i) = 0.56 nm). Tritiated NBI-42902 binds with high affinity (K(d) = 0.19 nm) to a single class of binding sites and can be disp...
T76350 [D-Glp1,D-Phe2,D-Trp3,6]-LH-RH
[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Glp1,D-Phe2,D-Trp3,6]-LH-RH acts as a GnRH receptor antagonist [1] .
T76351 [D-Ala6]-LH-RH
[D-Ala6]-LH-RH, a Luteinizing-hormone-releasing hormone (LHRH) analogue, functions as a gonadotropin-releasing hormone (GnRH) receptor agonist [1].
T76348 [D-Lys6]-LH-RH
[D-Lys6]-LH-RH is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Lys6]-LH-RH acts as a GnRH receptor agonist [1] .
T28795 SKI2496 SKI 2496,SKI-2496
SKI2496 is a potent and orally bioavailableantagonist of Gonadotropin-Releasing Hormone Receptor (hGnRHR IC50 = 0.46 nM; max. LH inh. inh. (%, h)= 84%, 12h; LH inh. (24h) = 76%.). SKI2496 exhibits more selective antagoni...
T70309 Dicetrorelix pamoate
Dicetrorelix pamoate is a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity. GnRH induces the production and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH)...
TP1936 RFRP-3(human) RFRP 3 (human)
Agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). Homolog of gonadotropin-inhibitory hormone (GnIH); inhibits activity of gonadotropin-releasing hormone (GnRH) neurons.
T76339 Kisspeptin 13
Kisspeptin 13 is a GPR54 and GnRH receptor activator, an endogenous active isoform. Kisspeptin 13 enhances memory and can be used in Alzheimer's disease research [1] .
T70775 Zoptarelin doxorubicin
Zoptarelin doxorubicin, also known as AEZS-108, is an LHRH agonist. Zoptarelin doxorubicin is a peptide agonist of the gonadotropin releasing hormone-1 receptor (GnRH-1R) that is conjugated to the anthracycline antibio...
T76436 [MePhe7]-Neurokinin B
[MePhe7]-Neurokinin B is an neurokinin NK-3 receptor ( NK3R ) agonist with an IC 50 value of 3 nM. [MePhe7]-Neurokinin B is a potential regulator of pulsatile gonadotropin-releasing hormone (GnRH) secretion via activatio...
T81485 Phoenixin-14 TFA PNX-14 TFA
Phoenixin-14 TFA (PNX-14) is a blood-brain barrier (BBB)-penetrable neuropeptide with anxiolytic, cardioprotective, and neuroprotective properties. It modulates pituitary gonadotrophin release by enhancing gonadotropin-r...
T76047 TAK-683 TFA
TAK-683 TFA is a potent full KISS1 receptor (KISS1R) agonist ( IC 50 =170 pM) with improved metabolic stability. TAK-683 TFA is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC 50 values of ...
T76048 TAK-683 acetate
TAK-683 acetate is a potent full KISS1 receptor (KISS1R) agonist ( IC 50 =170 pM) with improved metabolic stability. TAK-683 acetate is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC 50 va...
T69492 Ozarelix
Ozarelix is a fourth generation GnRH antagonist, induces apoptosis in hormone refractory androgen receptor negative prostate cancer cells modulating expression and activity of death receptors. Mechanistically, LHRH antag...
T35794 Kisspeptin-54 (human) (trifluoroacetate salt)
Kisspeptin-54 is a peptide ligand of the orphan G protein-coupled receptor GPR54 (Kis = 1.81 and 1.45 nM for rat and human receptors, respectively).1 It is a 54 amino acid peptide encoded by the metastasis suppressor gen...

Compounds

Fertirelin
TP1288
Synonym:
Target: Others
Alarelin Acetate
T1494
Synonym: Alarelin
Target: GNRH Receptor
Linzagolix
T27837
Synonym:
Target: GNRH Receptor
Cetrorelix Acetate
T5520
Synonym: Cetrorelix
Target: GNRH Receptor
Relugolix
T3630
Synonym: RVT-601,TAK-385
Target: GNRH Receptor
(R)-Elagolix
T11174
Synonym: NBI-56418
Target: GNRH Receptor
Goserelin acetate
T4102
Synonym: Fertilan,ICI-118630 acetate,Zoladex
Target: Apoptosis, GNRH Receptor
Elagolix sodium
T5031
Synonym: NBI-56418 sodium
Target: GNRH Receptor
Abarelix
T10217L
Synonym: R3827,PPI 149
Target: GNRH Receptor
Cetrorelix diacetate
T5520L
Synonym: NS-75A,SB-075 acetate,SB-075 diacetate,Cetrorelix acetate,NS-75A diacetate
Target: GNRH Receptor
Histrelin
T21308
Synonym: Supprelin LA,Histrelin Acetate
Target: Others
AG 045572
T22025
Synonym:
Target: P450, GNRH Receptor
Ganirelix Acetate
TP2337
Synonym:
Target: GNRH Receptor
Kisspeptin 234 acetate(1145998-81-7 free base)
TP1896L1
Synonym:
Target: GPR, Kisspeptin
BAY-784
T10475
Synonym:
Target: Others
T 98475
T23412
Synonym:
Target: Others
GnRH antagonist 2
T37003
Synonym:
Target:
Kisspeptin 234
TP1896
Synonym:
Target:
NBI-42902
T69383
Synonym:
Target:
[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH
T76350
Synonym:
Target:
[D-Ala6]-LH-RH
T76351
Synonym:
Target:
[D-Lys6]-LH-RH
T76348
Synonym:
Target:
SKI2496
T28795
Synonym: SKI 2496,SKI-2496
Target:
Dicetrorelix pamoate
T70309
Synonym:
Target:
RFRP-3(human)
TP1936
Synonym: RFRP 3 (human)
Target:
Kisspeptin 13
T76339
Synonym:
Target:
Zoptarelin doxorubicin
T70775
Synonym:
Target:
[MePhe7]-Neurokinin B
T76436
Synonym:
Target:
Phoenixin-14 TFA
T81485
Synonym: PNX-14 TFA
Target:
TAK-683 TFA
T76047
Synonym:
Target:
TAK-683 acetate
T76048
Synonym:
Target:
Ozarelix
T69492
Synonym:
Target:
Kisspeptin-54 (human) (trifluoroacetate salt)
T35794
Synonym:
Target:

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPK-00395 FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differen...
TMPK-00393 FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi) Human HEK293
Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differen...
TMPY-02393 Thimet Oligopeptidase/THOP1 Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
THOP1, also known as Thimet oligopeptidase 1, Thimet oligopeptidase, EC 3.4.24.15, or EP24.15, is a zinc(II) endopeptidase implicated in the processing of numerous physiological peptides. As an intracellular enzyme, high...
TMPY-04307 GNRH2 Protein, Human, Recombinant (hFc) Human HEK293
GNRH2 (Gonadotropin-Releasing Hormone 2) is a Protein Coding gene. This gene is a member of the gonadotropin-releasing hormone (GnRH) gene family. Proteins encoded by members of this gene family are proteolytically cleav...
TMPH-01210 DENR Protein, Human, Recombinant (His & SUMO) Human E. coli
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required...
TMPH-01209 DENND1A Protein, Human, Recombinant (His & SUMO) Human E. coli
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required...
TargetMol