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GPCR19

The G protein-coupled bile acid receptor 1 (GPBAR1) also known G-protein coupled receptor 19 (GPCR19), membrane-type receptor for bile acids (M-BAR) or TGR5 as is a protein that in humans is encoded by the GPBAR1 gene.
Cat. No. Product name CAS No. Purity Chemical Structure
T11662L INT-777 1199796-29-6 98%
INT-777 is a potent agonist of TGR5 (EC50: 0.82 μM).
T2968 Hyodeoxycholic acid 83-49-8 98%
Hyodeoxycholic Acid has been used in trials studying the treatment of Hypercholesterolemia.
T4352 SB756050 447410-57-3 98%
SB756050 is a specific TGR5 agonist.
T29078 Ursodeoxycholic acid sodium 2898-95-5 98%
Ursodeoxycholic acid sodium is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts a...
T8818 TC-G 1005 1415407-60-1 98%
TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and re...
T4083 BAR501 1632118-69-4 98%
BAR501 is an effective and specific GPBAR1 agonist (EC50: 1 μM).
T2965 Deoxycholic acid 83-44-3 98%
Deoxycholic acid is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent t...
T7428 SBI-115 882366-16-7 98%
SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5
T5077 Deoxycholic acid sodium salt 302-95-4 98%
Sodium Desoxycholate can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
TQ0252 BAR502 1612191-86-2 98%
BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).
T1824 TGR5 Receptor Agonist 1197300-24-5 98%
TGR5 is a potent TGR5(GPCR19) agonist.
T8752 BAR 501 impurity 1632118-70-7 98%
BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR501...
TP1949L PEN (human) aceate 98%
PEN (human) aceate, one of the most abundant hypothalamic neuropeptide and derived from the proprotein ProSAAS, is an endogenous ligand of GPR83.
INT-777
T11662L
INT-777 is a potent agonist of TGR5 (EC50: 0.82 μM).
Hyodeoxycholic acid
T2968
Hyodeoxycholic Acid has been used in trials studying the treatment of Hypercholesterolemia.
SB756050
T4352
SB756050 is a specific TGR5 agonist.
Ursodeoxycholic acid sodium
T29078
Ursodeoxycholic acid sodium is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts a...
TC-G 1005
T8818
TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and re...
BAR501
T4083
BAR501 is an effective and specific GPBAR1 agonist (EC50: 1 μM).
Deoxycholic acid
T2965
Deoxycholic acid is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent t...
SBI-115
T7428
SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5
Deoxycholic acid sodium salt
T5077
Sodium Desoxycholate can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
BAR502
TQ0252
BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).
TGR5 Receptor Agonist
T1824
TGR5 is a potent TGR5(GPCR19) agonist.
BAR 501 impurity
T8752
BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR501...
PEN (human) aceate
TP1949L
PEN (human) aceate, one of the most abundant hypothalamic neuropeptide and derived from the proprotein ProSAAS, is an endogenous ligand of GPR83.