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GPCR/G Protein GPCR19

GPCR19

The G protein-coupled bile acid receptor 1 (GPBAR1) also known G-protein coupled receptor 19 (GPCR19), membrane-type receptor for bile acids (M-BAR) or TGR5 as is a protein that in humans is encoded by the GPBAR1 gene.
Cat No. product name
T1824 TGR5 Receptor Agonist TGR5 is a potent TGR5(GPCR19) agonist.
T4083 BAR 501 BAR501 is an effective and specific GPBAR1 agonist (EC50: 1 μM).
T4352 SB-756050 SB756050 is a specific TGR5 agonist.
T5100 DJ-V159 DJ-V159 is an agonist for G protein-coupled receptor family C group 6 member A (GPRC6A).
T5077 Sodium Desoxycholate Sodium Desoxycholate can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
T7428 SBI-115 SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5
TQ0252 BAR502 BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).
T2968 Hyodeoxycholic acid Hyodeoxycholic Acid has been used in trials studying the treatment of Hypercholesterolemia.
T11662L INT-777 INT-777 is a potent agonist of TGR5 (EC50: 0.82 μM).
TGR5 Receptor Agonist
T1824CAS 1197300-24-5
TGR5 is a potent TGR5(GPCR19) agonist.
BAR 501
T4083CAS 1632118-69-4
BAR501 is an effective and specific GPBAR1 agonist (EC50: 1 μM).
SB-756050
T4352CAS 447410-57-3
SB756050 is a specific TGR5 agonist.
DJ-V159
T5100CAS 2253744-53-3
DJ-V159 is an agonist for G protein-coupled receptor family C group 6 member A (GPRC6A).
Sodium Desoxycholate
T5077CAS 302-95-4
Sodium Desoxycholate can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
SBI-115
T7428CAS 882366-16-7
SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5
BAR502
TQ0252CAS 1612191-86-2
BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).
Hyodeoxycholic acid
T2968CAS 83-49-8
Hyodeoxycholic Acid has been used in trials studying the treatment of Hypercholesterolemia.
INT-777
T11662LCAS 1199796-29-6
INT-777 is a potent agonist of TGR5 (EC50: 0.82 μM).