T60184 |
TUG-499
|
1206629-08-4
|
99.59%
|
|
TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) agonist (EC50: 7.39).TUG-499 has an affinity for FFAR1 or GPR40 over the related receptors FFA...
|
T27850 |
LP-471756
|
413605-11-5
|
99.59%
|
|
LP-471756 is a specific antagonist of GPR139 and inhibits LP-360924-stimulated cAMP production (IC50 = 640 nM).
|
T15388 |
GLPG0974
|
1391076-61-1
|
99.58%
|
|
GLPG0974 is an antagonist of FFA2/GPR43 with IC50 of 9 nM.
|
T8642 |
4-CMTB
|
300851-67-6
|
99.57%
|
|
4-CMTB is a selective agonist of FFA2 and GPR43.It also is a positive allosteric modulator (pEC50=6.38).
|
TP1996 |
MCH(human, mouse, rat)
|
128315-56-0
|
99.55%
|
|
MCH(human, mouse, rat) is a potent endogenous agonist at melanin-concentration hormone (MCH) receptors (IC50 values are 0.3 and 1.5 nM and EC50 values are 3.9 an...
|
T6399 |
AZD1981
|
802904-66-1
|
99.54%
|
|
AZD1981 is an effective and specific CRTh2 (DP2) receptor antagonist (IC50: 4 nM), showing >1000-fold selectivity over more than 340 other enzymes and receptors,...
|
T10889 |
CRTh2 antagonist 2
|
780763-95-3
|
99.53%
|
|
CRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, IC50≤10 nM. CRTh2 antagonist 2 can be used to study the direction of androgenic alopecia.
|
T9162 |
CID1231538
|
354126-20-8
|
99.51%
|
|
CID1231538 is a potent GPR35 antagonist.
|
T19438 |
Myristyl nicotinate
|
273203-62-6
|
99.50%
|
|
Myristyl nicotinate (Tetradecyl nicotinate) is an ester prodrug being developed for delivery of nicotinic acid (NIC) into the skin for prevention of actinic kera...
|
T9317 |
TAK-041
|
1929519-13-0
|
99.49%
|
|
TAK-041 (NBI-1065846) is a potent and selective GPR139 agonist.
|
T1237 |
Azathioprine
|
446-86-6
|
99.49%
|
|
Azathioprine (BW 57-322), an immunosuppressive agent, inhibits purine synthesis and GTP-binding protein Rac1 activation.
|
T60199 |
NCRW0005-F05
|
342779-66-2
|
99.48%
|
|
NCRW0005-F05 is a potent agonist of orphan G-protein coupled receptor GPR139 with an IC 50 value of 0.21 μM. NCRW0005-F05 can be used to research diabetes, obesi...
|
T27328 |
FL104
|
885672-81-1
|
99.46%
|
|
FL104 is a potent agonist of small-molecule urotensin II receptor, pEC50= 7.11.
|
T8329 |
AR 231453
|
733750-99-7
|
99.45%
|
|
AR 231453 is a selective and orally available GPR119 agonist,can stimulate β-cell replication and improve islet graft function.
|
T9437 |
1-methoxycyclopropanecarboxylic acid
|
100683-08-7
|
99.44%
|
|
1-methoxycyclopropanecarboxylic acid is an agonist of free fatty acid receptor 3 (FFAR3, human).
|
T7796 |
TUG-1375
|
2247372-59-2
|
99.41%
|
|
TUG-1375 is an Agonist of Thiazolidine Free Fatty Acid Receptor 2
|
T12883 |
Fezagepras
|
1002101-19-0
|
99.38%
|
|
Fezagepras (Setogepram) is an orally active GPR40 agonist and is an antagonist or inverse agonist of GPR84 with anti-inflammatory, anti-fibrotic, and anti-prolif...
|
T13423L |
(1S,2R)-2-PCCA
|
|
99.34%
|
|
(1S,2R)-2-PCCA is a novel and potent small molecule GPR88 receptor agonist with an EC50 value of 3 nM in the non-cellular system and 603 nM in the cellular syste...
|
TP1896L1 |
Kisspeptin 234 acetate(1145998-81-7 free base)
|
TP1896L1
|
99.34%
|
|
Kisspeptin 234 acetate is a kisspeptin receptor antagonist. Kisspeptin 234 inhibits kisspeptin-10 stimulation of IP (IC50 = 7 nM) and release of GnRH.
|
T67892 |
BTB09089
|
245728-44-3
|
99.31%
|
|
BTB09089 (GPR65 agonist ) is a T cell death-associated gene 8 (TDAG8/GPR65)-specific agonist.BTB09089 induces TDAG8 expression and regulates cytokine production ...
|