T10084 |
CRTh2 antagonist 1
|
1379445-54-1
|
97.39%
|
|
CRTh2 antagonist 1 is a CRTh2 antagonist (IC50: 89 nM).
|
T77601 |
(2-{[2-(2-fluorophenoxy)ethyl]sulfanyl}-1H-benzimidazol-1-yl)acetic acid
|
303134-93-2
|
97.13%
|
|
(2-{[2-(2-fluorophenoxy)ethyl]sulfanyl}-1H-benzimidazol-1-yl)acetic acid is a prostaglandin-like CRTH2 antagonist with an IC50 < 10 μM, which can be used in stud...
|
T10938 |
D-Kynurenine
|
13441-51-5
|
97.08%
|
|
D-Kynurenine (ZINC901103) is a metabolite of D-tryptophan and an agonist of GPR109B. D-Kynurenine activates AhR and promotes the conversion of the epithelium to ...
|
T15718 |
Latanoprost acid
|
41639-83-2
|
96.97%
|
|
Latanoprost acid is a selective agonist of prostanoid receptors and inhibits RANKL-induced osteoclastogenesis and function through the inhibition of c-fos/NFATc1...
|
T11411 |
GLPG1205
|
1445847-37-9
|
95.97%
|
|
GLPG1205 is a potent, orally active GPR84 (G protein-coupled receptor) antagonist with anti-inflammatory activity. GLPG1205 shows good PK/PD characteristics and ...
|
TP1970L |
Prosaptide TX14(A) acetate
|
TP1970L
|
95.29%
|
|
Prosaptide TX14(A) acetate is a potent GPR37L1 and GPR37 agonist. Prosaptide Tx14(A) TFA increases both ERK1 and ERK2 phosphorylation in Schwann cells.
|
T50078 |
2-(pentylsulfanyl)pyrimidine-4,6-diol
|
489403-70-5
|
95.00%
|
|
2-(pentylsulfanyl)pyrimidine-4,6-diol is a novel GRP84 agonist.
|
T15810 |
LY2922470
|
1423018-12-5
|
93.34%
|
|
LY2922470 reduces glucose levels along with significant enhancements in insulin and GLP-1, which is the potential for the treatment of type 2 diabetes mellitus (...
|
TN2268 |
Tetrahydromagnolol
|
20601-85-8
|
100%
|
|
Tetrahydromagnolol can activate cannabinoid (CB) receptors.
|
T34967 |
TUG-469
|
1236109-67-3
|
100%
|
|
TUG-469 is an agonist of free fatty acid 1(FFA) receptor.
|
T67791 |
BMS-903452
|
1339944-47-6
|
100%
|
|
BMS-903452 is a potent and selective GPR119 agonist with EC50 of 14 nM. BMS-903452 is indicated for the treatment of acute and chronic rodent diabetes. GPR119 wa...
|
T8004 |
SNAP 94847 hydrochloride
|
1781934-47-1
|
100%
|
|
SNAP 94847 hydrochloride is a melanin-concentrating hormonereceptor1 (MCHR1) antagonist(Ki= 2.2 nM)
|
TP1737L |
Urotensin II (114-124), human acetate
|
TP1737L
|
100%
|
|
Urotensin II (114-124), human acetate is an 11-amino acid residue peptide, is a potent vasoconstrictor and agonist for the orphan receptor GPR14.
|
T2036 |
6-OAU
|
83797-69-7
|
|
|
6-OAU (GTPL5846)(GTPL5846; 6-n-octylaminouracil) is a surrogate agonist of GPR84; activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an E...
|
TN1560 |
Dehydroeffusol
|
137319-34-7
|
|
|
Dehydroeffusol (Dehydro Effusol) possesses anti-cancer, anxiolytic and sedative properties. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity...
|
T4312 |
GPR120 Agonist 2
|
1234844-11-1
|
|
|
GPR120 Agonist 2 is a potent and selective GPR120 receptor agonist.
|
T12095 |
Monomethyl fumarate
|
2756-87-8
|
|
|
Monomethyl fumarate is a potent agonist of GPR109A .
|
T36818 |
Questiomycin A
|
1916-59-2
|
|
|
Questiomycin A is an antibiotic produced in crème fraiche with antibacterial and anticancer activities. Questiomycin A suppresses expression of GRP78, a cell-pro...
|
T2351 |
Fasiglifam
|
1000413-72-8
|
|
|
Fasiglifam (TAK875) is a potent, selective and orally bioavailable GPR40 agonist.
|
T5406 |
SNAP 94847
|
487051-12-7
|
|
|
SNAP 94847 (SNAP-94847) is a selective and competitive MCH1 receptor (MCH1-R) antagonist (Ki: 2.2 nM). It has anxiolytic and antidepressant activity and reduces ...
|