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Cat No. | Product Name | Synonyms | Targets |
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T37223 | Glucagon Receptor Antagonist I | ||
Glucagon receptor antagonist I is a competitive antagonist of the glucagon receptor (GCGR; IC50 = 181 nM). It blocks glucagon-induced glycogenolysis in primary human hepatocytes and isolated liver. Glucagon receptor anta... | |||
T36580 | Glucagon Receptor Antagonist Inactive Control | ||
Glucagon Receptor Antagonist Inactive Control is a Glucagon receptor antagonist that can be used in related research in the field of life sciences. Its product number is T36580 and CAS number is 362482-00-6. | |||
T11416 | Glucagon receptor antagonists-5 | Others | |
Glucagon receptor antagonists-5 is an orally bioavailable indazole-based glucagon receptor antagonist (Ki: 32 nM). It has potential for the treatment of type 2 diabetes mellitus (T2DM). | |||
T11415 | Glucagon receptor antagonists-3 | Others | |
Glucagon receptor antagonist -3 is a highly effective glucagon receptor antagonist. | |||
T11414 | Glucagon receptor antagonists-2 | Others | |
Glucagon receptor antagonist -2 is a highly effective glucagon receptor antagonist. | |||
T11413 | Glucagon receptor antagonists-1 | Others | |
Glucagon receptor antagonist -1 is a highly effective glucagon receptor antagonist. | |||
TQ0239 | PF-06291874 | Glucagon receptor antagonists-4 | Glucagon Receptor |
PF-06291874 (Glucagon receptor antagonists-4) (Glucagon receptor antagonists-4) is a highly effective and orally active antagonist of the glucagon receptor. | |||
T15389L | Glucagon (1-29), bovine, human, porcine hydrochloride | Porcine glucagon hydrochloride,Glucagon hydrochloride | Glucocorticoid Receptor , Glucagon Receptor |
Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. It activates HNF4α and increases HNF4α phosphorylation. Glucagon (1-29), bovine, human, porcine hydrochloride(Po... | |||
TQ0124 | BETP | Glucagon Receptor | |
BETP is an agonist of GLP-1 receptor (EC50s: 0.66 and 0.755 μM for human and rat GLP-1 receptor). | |||
T11845 | LGD-6972 | Glucagon Receptor | |
LGD-6972 is an antagonist of glucagon receptor. | |||
T9579 | GLP-1 receptor agonist 9 | Glucagon Receptor | |
1H-Benzimidazole-6-carboxylic acid is a GLP-1 receptor agonist. | |||
T7364 | NNC-0640 | Glucagon Receptor | |
NNC-0640 is a negative allosteric modulator of Human Glucagon Receptor with an IC50 of 69.2 nM. | |||
T8748 | Exendin-4 acetate | Glucagon Receptor | |
Exendin-4 acetate is a 39 amino acid peptide.Exendin-4 acetate is a long-acting GLP-1 receptor agonist(IC50 = 3.22 nM). | |||
T3984 | GLP-1(7-36), amide | MKC 253,Human GLP-1-(7-36)-amide,Glucagon-like Peptide 1 (7-36) amide,Glucagon-Like Peptide (GLP) I (7-36), amide, human,GLP-1(7-36),GLP-1-(7-36)-amide | Glucagon Receptor |
GLP-1(7-36), amide (MKC 253) is a peptide hormone released from intestinal L-cells upon nutrient consumption. It binds the GLP-1 receptor in the pancreas and displays various antidiabetic effects by potentiating glucose-... | |||
T19850 | Semaglutide | Glucagon Receptor | |
Semaglutide is a glucagon-like peptide 1 receptor (GLP-1R) agonist(EC50 of 6.2 pM in a reporter assay using BHK cells expressing the human receptor). | |||
TP2252 | GLP-1 (9-36) amide | Glucagon Receptor | |
antagonist at the human GLP-1 receptor | |||
T3422 | GRA Ex-25 | GRA-Ex-25 | Glucagon Receptor |
GRA Ex-25 (GRA-Ex-25) is an inhibitor of glucagon receptor. | |||
T3967 | Exendin-4 | Exenatide,Exenatide Acetate | Glucagon Receptor |
Exendin-4 (Exenatide) is a glucagon-like peptide-1 receptor (GLP-1) agonist (IC50: 3.22 nM). Exenatide is a 39 amino acid peptide. Compared to GLP-1, exenatide has a longer half-life of 2.4 hours. | |||
TP1039 | Secretin (33-59), rat | Secretin (rat) | Glucagon Receptor |
Secretin (33-59), rat (Secretin (rat)) is a classical hormone in the gastrointestinal system and a neuropeptide. | |||
TP1469 | Lixisenatide acetate (320367-13-3 free base) | Lixisenatide acetate | Glucagon Receptor |
Lixisenatide acetate is a receptor agonist similar to glucagon-like peptide-1 (glp-1) for the treatment of type 2 diabetes mellitus (T2DM). | |||
T6876 | Liraglutide | Liraglutidum,Victoza,Liraglutida,NN2211 | Glucagon Receptor |
Liraglutide (Liraglutida) is a long-acting GLP-1 receptor agonist. | |||
TP2100 | Avexitide | Exendin-3 (9-39) amide,Exendin (9-39) | Glucagon Receptor |
Avexitide (Exendin-3 (9-39) amide) (Exendin (9-39)) is a specific and competitive antagonist of glucagon-like peptide-1 (GLP-1) receptor. | |||
TP1376 | GLP-1(7-37) acetate(106612-94-6 free base) | GLP-1(7-37) acetate | Others , Glucagon Receptor |
Glp-1(7-37) acetate is an intestinal insulin hormone that enhances glucose-induced insulin secretion. | |||
T60047 | V-0219 | Glucagon Receptor | |
V-0219 is a positive allosteric modulator of GLP-1 and can be used in studies about obesity-associated diabetes. | |||
TP1103 | Cotadutide acetate | MEDI0382 acetate,Cotadutide acetate (1686108-82-6 Free base) | Glucagon Receptor |
Cotadutide acetate (MEDI0382 acetate) is a potent peptide dual agonist of glucagon-like peptide-1 (GLP-1) and glucagon receptor with EC50 of 6.9 pM and 10.2 pM, respectively. | |||
T22893 | L-168049 | L-168,049 | Glucagon Receptor |
L-168049 is a selective and non-competitive antagonist of human glucagon receptor with IC50s of 3.7 nM, 63 nM, and 60 nM for human, murine, and canine, respectively. | |||
T76559 | Survodutide | BI 456906 | Glucagon Receptor |
Survodutide (BI 456906) is a dual agonist of glucagon and glucagon-like peptide 1 (GLP-1) receptor (GLP Receptor) that reduces body weight in HbA1c16 diabetes. | |||
T28182 | NNC 92-1687 | NNC92-1687,NNC-92-1687 | Glucagon Receptor |
NNC 92-1687 is a selective glucagon receptor antagonist that can be used to study type 2 diabetes. | |||
T76279 | Retatrutide | LY3437943 | Glucagon Receptor |
Retatrutide (LY3437943) is a triple agonist of the glucagon receptor, glucose-dependent insulinotropic polypeptide receptor, and glucagon-like peptide-1 receptor (GLP-1R), and inhibits GCGR, GIPR, and GLP-1R.Retatrutide ... | |||
T76279L1 | Retatrutide sodium salt | Retatrutide sodium salt(2381089-83-2 free base),LY3437943 sodium salt | Glucagon Receptor |
Retatrutide sodium salt is a potent triple agonist peptide for glucagon receptor (GCGR), glucose-dependent proinsulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R) Retatrutide sodium s... | |||
T8355 | Exenatide | Exendin-4,Extendin-4 | Glucagon Receptor |
Exenatide (Extendin-4) is a glucagon-like protein-1 (GLP-1) receptor agonist. | |||
T60047L | V-0219 hydrochloride | V-0219 hydrochloride(878453-71-5 Free base) | Glucagon Receptor |
V-0219 hydrochloride, an orally-active positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R), is utilized in obesity-associated diabetes research. | |||
T11408 | Orforglipron | LY3502970,GLP-1 receptor agonist 1 | Glucagon Receptor |
Orforglipron (LY3502970; GLP-1 receptor agonist 1) is an orally available glucagon-like peptide (GLP-1) receptor agonist for the study of obesity and type 1 diabetes in adults. | |||
T12431 | PF-06882961 | Glucagon Receptor | |
PF-06882961 is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist. | |||
T19850L | Semaglutide Acetate | Semaglutide Acetate(910463-68-2 Free base) | Glucagon Receptor |
Semaglutide Acetate is an agonist of a glucagon-like peptide 1 (GLP-1) receptor and can be used in studies about the treatment of type 2 diabetes. | |||
T36579 | GLP-1R Agonist DMB | Glucagon Receptor | |
GLP-1R Agonist DMB is an agonist of glucagon-like peptide 1 receptor (GLP-1R; KB = 26.3 nM for the recombinant human receptor). | |||
T8876 | PF-06882961 Tris | UNII-2HJV78O0SS | Glucagon Receptor |
PF-06882961 Tris (UNII-2HJV78O0SS) is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist. | |||
TP1976L | Oxyntomodulin acetate | Glucagon Receptor | |
Oxyntomodulin acetate, a 37-amino acid peptide hormone, is a glucagon-like peptide 1 (GLP-1) receptor agonist[1]. | |||
T14130 | Adomeglivant | LY2409021 | Glucagon Receptor |
Adomeglivant (LY2409021) is a potent and selective glucagon receptor antagonist. Which is used in clinical trial for type 2 diabetes mellitus. | |||
TP2100L | Avexitide acetate | Exendin 9-39 acetate,Avexitide acetate(133514-43-9 Free base) | Glucagon Receptor |
Avexitide acetate (exendin 9-39) is a potent glucagon-like peptide 1 receptor (GLP-1R) antagonist for the study of post-obesity hypoglycemia. | |||
T63166L | (S, R)-LSN 3318839 | (S, R)-LSN 3318839(Isomer-2764704-18-7) | Glucagon Receptor |
(S, R)-LSN 3318839 is an allosteric modulator of the glucagon-like peptide-3318839 receptor (GLP-1R) that has demonstrated powerful hypoglycemic effects in animal models alone or in combination with sitagliptin. | |||
T78097L | Mazdutide acetate(2259884-03-0 free base) | Mazdutide acetate(2259884-03-0 free base),OXM-3 acetate,LY-3305677 acetate,IBI-362 acetate | Glucagon Receptor |
Mazdutide acetate is a potent co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR), a gastrin-regulating hormone analog.Mazdutide acetate stimulates insulin secretion from mouse pancreatic islets, an... | |||
T15387 | GLP-1R Antagonist 1 | Glucagon Receptor | |
GLP-1R Antagonist 1 is an orally active, CNS penetrant and non-competitive glucagon-like peptide 1 receptor (GLP-1R) antagonist (IC50: 650 nM). | |||
T63166 | LSN3318839 | LSN-3318839,LSN 3318839 | Glucagon Receptor |
LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and can be used to lower blood glucose. | |||
TP1111 | Tirzepatide | LY-3298176 | Glucagon Receptor |
Tirzepatide (LY-3298176) is a dual agonist of glucose-dependent polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor with neuroprotective activity for the study of diabetes and obesity. | |||
T12055 | MK 0893 | Others | |
MK 0893 is a potent, selective antagonist of glucagon receptor. | |||
T28057 | MK3577 | MK-3577,MK 3577 | |
MK3577 is a glucagon receptor antagonist. | |||
T30299 | BAY-27-9955 | BAY 279955,BAY27-9955,BAY-279955,BAY 27-9955 | |
BAY-27-9955 is a glucagon receptor antagonist. | |||
T25711 | LGD-6972 sodium | LGD 6972 sodium | |
LGD-6972 sodium is a glucagon receptor antagonist. | |||
T70279 | Cotadutide | ||
Cotadutide is a dual receptor agonist that modifies the activity of glucagon and glucagon-like peptide-1 (GLP-1). |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3896 | Shanzhiside methyl ester | Glucagon Receptor | |
Shanzhiside methylester reduces neuropathic pain by activating spinal GLP-1 receptors and subsequently stimulating microglial β-endorphin expression via the p38 MAPK signaling. | |||
T37298 | Spinacine | Endogenous Metabolite | |
Spinacine has been isolated from spinach and the roots of Panax ginseng. This conformationally constrained amino acid is a structural element in certain biologically active compounds as glucagon antagonists and angiotens... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-06864 | GLP1R Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Glucagon-like peptide (GLP)-1 receptor is encoded by GLP1R. GLP1R plays a critical role in mediating the biological actions of GLP1 in mammals and fish. The neuronal GLP1Rs mediate body weight and anorectic effects of li... | |||
TMPH-01386 | GLP2R Protein, Human, Recombinant (His) | Human | HEK293 |
This is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. | |||
TMPH-03301 | GLP1R Protein, Rat, Recombinant (E. coli, His) | Rat | E. coli |
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a ... | |||
TMPH-02676 | GLP1R Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a ... | |||
TMPH-01385 | GLP1R Protein, Human, Recombinant (His) | Human | HEK293 |
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a ... | |||
TMPH-01384 | GLP1R Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a ... | |||
TMPH-01382 | GCGR Protein, Human, Recombinant (E. coli, His & Myc) | Human | E. coli |
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and g... | |||
TMPH-02675 | GCGR Protein, Mouse, Recombinant (GST) | Mouse | E. coli |
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and g... | |||
TMPH-01383 | GCGR Protein, Human, Recombinant (His & Myc) | Human | HEK293 |
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and g... |