Glucagon Receptor

The glucagon receptor is a 62 kDa protein that is activated by glucagon and is a member of the class B G-protein coupled family of receptors, coupled to G alpha i, Gs and to a lesser extent G alpha q. Stimulation of the receptor results in activation of adenylate cyclase and increased levels of intracellular cAMP. In humans, the glucagon receptor is encoded by the GCGR gene.

Cat. No.	Product name	CAS No.	Purity
TQ0239	PF-06291874	1393124-08-7	99.14%
TQ0239	PF-06291874 (Glucagon receptor antagonists-4) (Glucagon receptor antagonists-4) is a highly effective and orally active antagonist of the glucagon receptor.
T6876	Liraglutide	204656-20-2	99.04%
T6876	Liraglutide (Liraglutida) is a long-acting GLP-1 receptor agonist.
T28182	NNC 92-1687	22903-37-3	98.93%
T28182	NNC 92-1687 is a selective glucagon receptor antagonist that can be used to study type 2 diabetes.
TP1376	GLP-1(7-37) acetate(106612-94-6 free base)	1450806-98-0	98.89%
TP1376	Glp-1(7-37) acetate is an intestinal insulin hormone that enhances glucose-induced insulin secretion.
T0294	6α-Methylprednisolone 21-hemisuccinate sodium salt	2375-03-3	98.69%
T0294	6α-Methylprednisolone 21-hemisuccinate sodium salt (Asmacortone), a water-soluble ester, is used for allergic, cardiac, and hypoxic emergencies.
T8748	Exendin-4 acetate	914454-01-6	98.65%
T8748	Exendin-4 acetate is a 39 amino acid peptide.Exendin-4 acetate is a long-acting GLP-1 receptor agonist(IC50 = 3.22 nM).
T19850L	Semaglutide Acetate	1997361-85-9	98.42%
T19850L	Semaglutide Acetate is an agonist of a glucagon-like peptide 1 (GLP-1) receptor and can be used in studies about the treatment of type 2 diabetes.
T76279	Retatrutide	2381089-83-2	98.31%
T76279	Retatrutide (LY3437943) is a triple agonist of the glucagon receptor, glucose-dependent insulinotropic polypeptide receptor, and glucagon-like peptide-1 receptor...
T77781	Lotiglipron	2401892-75-7	98.3%
T77781	Lotiglipron (PF-07081532) is an orally active and potent GLP-1R agonist that reduces blood glucose and body weight and may be useful in the study of type 2 diabe...
TP1103	Cotadutide acetate	TP1103	98.28%
TP1103	Cotadutide acetate (MEDI0382 acetate) is a potent peptide dual agonist of glucagon-like peptide-1 (GLP-1) and glucagon receptor with EC50 of 6.9 pM and 10.2 pM, ...
TP2071L	Bay 55-9837 acetate		98.27%
TP2071L	Bay 55-9837 acetate is a potent and highly selective VPAC2 agonist(Kd = 0.65 nM) and can be used in type 2 diabetes studies.
TQ0124	BETP	1371569-69-5	97.92%
TQ0124	BETP is an agonist of GLP-1 receptor (EC50s: 0.66 and 0.755 μM for human and rat GLP-1 receptor).
T7364	NNC-0640	307986-98-7	97.55%
T7364	NNC-0640 is a negative allosteric modulator of Human Glucagon Receptor with an IC50 of 69.2 nM.
TP1382L	HAEGTFTSDVS acetate	TP1382L	97.47%
TP1382L	HAEGTFTSDVS acetate is the first N-terminal 1-11 residues of GLP-1 which stimulates insulin secretion from pancreatic β-cells.
T3422	GRA Ex-25	307983-31-9	97.39%
T3422	GRA Ex-25 (GRA-Ex-25) is an inhibitor of glucagon receptor.
TP1111L	Tirzepatide Acetate(2023788-19-2 free base)	TP1111L	97.3%
TP1111L	Tirzepatide acetate is a dual GIP / GLP-1 receptor agonist.
T15389L	Glucagon (1-29), bovine, human, porcine hydrochloride	28270-04-4	95.65%
T15389L	Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. It activates HNF4α and increases HNF4α phosphorylatio...
T12431	PF-06882961	2230198-02-2	95.1%
T12431	PF-06882961 is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist.
T22893	L-168049	191034-25-0	100%
T22893	L-168049 is a selective and non-competitive antagonist of human glucagon receptor with IC50s of 3.7 nM, 63 nM, and 60 nM for human, murine, and canine, respectiv...
T60047L	V-0219 hydrochloride	T60047L	100%
T60047L	V-0219 hydrochloride, an orally-active positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R), is utilized in obesity-associated di...