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Cat No. | Product Name | Synonyms | Targets |
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T37908 | Glucocorticoid receptor agonist-1 | Glucocorticoid Receptor | |
Glucocorticoid receptor agonist-1 is a potent glucocorticoid receptor agonist with an IC50 of 2.8 nM[1]. | |||
T11417 | Glucocorticoid receptor agonist | Others | |
Glucocorticoid receptor agonist is an effective glucocorticoid receptor agonist. | |||
T67742 | EX-A5386 | Glucocorticoid receptor modulator-1 | Glucocorticoid Receptor |
EX-A5386 (Glucocorticoid receptor modulator-1) is a potent glucocorticoid receptor modulator, IC50/EC50<100nM. | |||
T63551 | Glucocorticoid receptor-IN-1 | ||
Glucocorticoid receptor-IN-1 is a selective regulator of the glucocorticoid receptor (GR) and exhibits anti-inflammatory activity. glucocorticoid receptor-IN-1 has good transcriptional repression, acting on hMMP1 ( IC50:... | |||
T63539 | Glucocorticoid receptor-IN-2 | ||
Glucocorticoid receptor-IN-2 is a selective regulator of the glucocorticoid receptor (GR) and exhibits anti-inflammatory activity. IC50: 0.171 nM) and also has some transcriptional activating effect on MMTV (EC50: 0.94 n... | |||
T72102 | Glucocorticoid receptor modulator 1 | ||
Glucocorticoid receptor modulator 1 is a potent, orally active, non-steroidal selective glucocorticoid receptor modulator, exhibiting IC50 values of 9 nM and 130 nM against NF-κB and AP-1, respectively. It effectively re... | |||
T74697 | Glucocorticoid receptor agonist-2 | ||
Glucocorticoid receptor agonist-2 (compound 21), a glucocorticoid receptor agonist exhibiting an IC50 value of 6.6 nM, serves as an active reference for ABBV-3373 [1]. This compound is instrumental in the synthesis of an... | |||
T15451 | GW-870086 | Glucocorticoid Receptor | |
GW-870086 is an effective anti-inflammatory agent. GW-870086 also plays a role in a glucocorticoid receptor agonist (pIC50: 10.1 in A549 cells expressing NF-κB). | |||
T14377 | AZD5423 | Glucocorticoid Receptor | |
AZD5423 is an inhaled, potent, selective, and non-steroidal modulator of glucocorticoid receptor (GR) and it effectively reduces allergen-induced responses in subjects with mild allergic asthma. | |||
T8777 | Beclometasone | BecloMethasone | Glucocorticoid Receptor |
Beclometasone is a prototype glucocorticoid receptor agonist. It is used topically as an anti-inflammatory agent and in aerosol form for the treatment of asthma. | |||
T14981 | Clobetasone butyrate | Glucocorticoid Receptor | |
Clobetasone butyrate, a synthetic glucocorticoid with topical anti-inflammatory activity, is effective in treating corticosteroid-responsive dermatoses, such as atopic dermatitis and psoriasis, especially within skin tis... | |||
T17217 | Vamorolone | VBP15 | Glucocorticoid Receptor , NF-κB |
Vamorolone (VBP15) is an orally active dissociative steroidal anti-inflammatory drug and membrane-stabilizer. Vamorolone improves muscular dystrophy without side effects. Vamorolone displays effective NF-κB inhibition an... | |||
T0820 | Triamcinolone acetonide | Aristogel,Azmacort,Aristoderm | Glucocorticoid Receptor |
Triamcinolone acetonide (Azmacort) is a Corticosteroid. The mechanism of action of triamcinolone acetonide is as a Corticosteroid Hormone Receptor Agonist. It is an anti-inflammatory glucocorticoid used topically in the ... | |||
T74116 | Glucocorticoid receptor agonist-1 Ala-Ala-Mal | ||
Glucocorticoid receptor agonist-1 Ala-Ala-Mal (compound 88), a glucocorticosteroid and glucocorticoid receptor agonist, can be conjugated with Adalimumab to formulate an ADC [1]. | |||
T77869 | Glucocorticoid receptor agonist-2 Ala-Ala-Mal | ||
Glucocorticoid receptor agonist-2 Ala-Ala-Mal (compound 79) serves as a precursor for synthesizing anti-inflammatory antibody-drug conjugate (ADC) molecules and acts as an active reference for ABBV-3373 [1]. | |||
T75016 | Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal | ||
Glucocorticoid Receptor Agonist-1 Phosphate Ala-Ala-Mal functions as a glucocorticoid receptor agonist, utilized in the formulation of anti-CD40 antibody agent conjugates (ADC). It serves as a research tool for exploring... | |||
T6502 | Fluocinonide | Lidex,Metosyn,Topsyn | Glucocorticoid Receptor |
Fluocinonide (Topsyn) (Vanos) is an effective glucocorticoid steroid, utilized in the treatment as the skin disorders anti-inflammatory agent. | |||
T77835 | Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br | ||
Glucocorticoid Receptor Agonist-1 Phosphate (Gly-Glu-Br) is an antibody-drug conjugate (ADC) linker utilized in the synthesis of ABBV-154, ABBV-927, ABBV-368, and related analogs [1]. | |||
T8396 | Prednisone acetate | Prednisone 21-acetate | Glucocorticoid Receptor |
Prednisone acetate (Prednisone 21-acetate) is a glucocorticoid receptor agonist with immunomodulating properties and anti-inflammatory. | |||
T0261 | Amcinonide | CL-34699 | Glucocorticoid Receptor , Annexin A |
Amcinonide (CL-34699) is a Corticosteroid. The mechanism of action of amcinonide is as a Corticosteroid Hormone Receptor Agonist. | |||
T1163 | Betamethasone valerate | Betnovate,Betaderm,Betamethasone 17-valerate,Luxiq | Glucocorticoid Receptor |
Betamethasone valerate (Luxiq) is a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. | |||
T82303 | Glucocorticoid receptor agonist-1 phosphate Gly-Glu TFA | ||
Glucocorticoid Receptor Agonist-1 Phosphate Gly-Glu (TFA) serves as a cleavable linker for the synthesis of Antibody-Drug Conjugates (ADCs). | |||
T0367 | Fluocinolone (Acetonide) | Fluocinolone acetonide,Flucort-N | Glucocorticoid Receptor |
Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders. It is usually employed as a cream, gel, lotion, or ointment. It has also been used topically in... | |||
T3316 | Fluorometholone | Fluoromethalone,Cortilet,Oxylone,Delmeson | Glucocorticoid Receptor |
Fluorometholone (Fluoromethalone) is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) and Flarex (Alcon). Fluorometholone acetate ophthalmic susp... | |||
T75130 | Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Br | ||
Glucocorticoid Receptor Agonist-1 Phosphate Ala-Ala-Br is a drug-linker conjugate for antibody-drug conjugates (ADCs), serving as a reaction reagent in the creation of anti-CD40 antibody agent conjugates [1]. | |||
T0181 | Loteprednol etabonate | Lotemax,Alrex | Glucocorticoid Receptor , Antibacterial , Antibiotic |
Loteprednol etabonate (Lotemax) is an ophthalmic analog of the corticosteroid prednisolone with anti-inflammatory activity. | |||
T1076 | Dexamethasone | MK 125,Prednisolone F,NSC 34521,Hexadecadrol | Glucocorticoid Receptor , Mitophagy , IL Receptor , SARS-CoV , Antibacterial , Antibiotic , Autophagy , Complement System |
Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist and an IL receptor modulator. Dexamethasone has anti-inflammatory and immunosuppressive activity and induces autophagy. Dexamethasone inhibits LPS-induced... | |||
T1749 | AL 082D06 | D-06,AL082D06 | Glucocorticoid Receptor |
AL 082D06 (D-06), a selective nonsteroidal glucocorticoid receptor (GR) antagonist (Ki: 210 nM), exhibits outstanding selectivity against AR, ER, MR and PR(Ki > 10 uM). | |||
T6713 | Ulipristal | Estrogen/progestogen Receptor , Progesterone Receptor | |
Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure. | |||
TQ0225 | Velsecorat | AZD7594,AZ13189620 | Glucocorticoid Receptor |
Velsecorat (AZD7594) is an effective and selective nonsteroidal glucocorticoid receptor modulator (IC50: 0.9 nM). | |||
T2526 | Ciclesonide | Zetonna,RPR251526,Omnaris,Alvesco | Glucocorticoid Receptor |
Ciclesonide (Alvesco)(RPR251526) is a glucocorticoid used for the treatment of obstructive airway diseases. | |||
T0094 | Budesonide | Entocort,Pulmicort,Rhinocort | Glucocorticoid Receptor |
Budesonide (Pulmicort), an anti-inflammatory corticosteroid, has shown the effective glucocorticoid activitie and few mineralocorticoid activities. According to reports, Budesonide has extensively inhibitory effects agai... | |||
T22367 | Methylprednisolone succinate | Methylprednisolone hemisuccinate,Methylprednisolone hydrogen succinate | Glucocorticoid Receptor |
Methylprednisolone succinate (Methylprednisolone hemisuccinate) is a synthetic glucocorticoid and is widely used as an anti-inflammatory agent. | |||
T1531 | Mometasone furoate | Sch32088 | Glucocorticoid Receptor |
Mometasone furoate (Sch32088) is a pregnadienediol derivative ANTI-ALLERGIC AGENT and ANTI-INFLAMMATORY AGENT that is used in the management of ASTHMA and ALLERGIC RHINITIS. It is also used as a topical treatment for ski... | |||
T21404 | Fluticasone furoate | Veramyst,Allermist,Avamys,Fluticasone furoate | Glucocorticoid Receptor |
Fluticasone furoate (Avamys) is a synthetic trifluorinated corticosteroid derived from fluticasone with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflammatory, anti-asthmatic activity, and low systemic exposure... | |||
T6580 | Meprednisone | SCH 4358,Methylprednisone,NSC 527579,Betanisona,Betapar | Glucocorticoid Receptor , Autophagy |
Betapar(Meprednisone (Betapar)) is a glucocorticoid and a methylated derivative of prednisone. | |||
T2527 | Ulipristal acetate | Ulipristal,CDB-2914 | Estrogen/progestogen Receptor , Progesterone Receptor , Autophagy |
Ulipristal acetate (CDB-2914) is an orally bioavailable, acetate salt of ulipristal, a selective progesterone receptor modulator with anti-progesterone activity. Ulipristal binds to the progesterone receptor (PR), thereb... | |||
T1102 | Mifepristone | C-1073,RU486,RU 38486 | Glucocorticoid Receptor , Estrogen/progestogen Receptor , Progesterone Receptor , NO Synthase , Autophagy |
Mifepristone (C-1073) is a Progestin Antagonist. The mechanism of action of mifepristone is as a Progestational Hormone Receptor Antagonist. | |||
T16079 | Mirodenafil | SK3530 | PDE |
Mirodenafil is a PDE-5 inhibitor developed for the treatment of erectile dysfunction. | |||
T1127 | Beclometasone dipropionate | Beclovent,Beclomethasone dipropionate,Beconase,Vancenase | Glucocorticoid Receptor |
Beclometasone dipropionate (Vancenase) is the dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone... | |||
T0947L | Dexamethasone Phosphate disodium | EGP-437,EGP437. Dex-Phos,EGP 437 | Glucocorticoid Receptor |
Dexamethasone Phosphate disodium (EGP437. Dex-Phos) is a water-soluble form of the synthetic glucocorticoid dexamethasone. | |||
T0208 | Prednisolone disodium phosphate | Prednisolone phosphate sodium,Prednisolone 21-phosphate disodium | Glucocorticoid Receptor |
Prednisolone disodium phosphate, a synthetic glucocorticoid, has immunomodulating and anti-inflammatory properties. | |||
T0188 | Fluticasone (propionate) | CCI-187881,Fluticasone propionate | Glucocorticoid Receptor , Virus Protease , Estrogen/progestogen Receptor , Phospholipase , Endogenous Metabolite |
Fluticasone propionate (CCI-187881), derived from fluticasone used to remedy asthma and allergic rhinitis, is a high affinity, selective GR (glucocorticoid receptor) agonist. | |||
T1559 | Betamethasone dipropionate | Diprolene AF,SCH 11460,Betamethasone 17,21-dipropionate,Diprolene,Diprosone | Glucocorticoid Receptor |
Betamethasone Dipropionate is the 17, 21-dipropionate ester of betamethasone, a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. Betamethasone dipropionate (SCH 11460) binds to sp... | |||
T0947 | Dexamethasone acetate | Dexamethasone 21-acetate,Dexamethason acetate,NSC 39471 | Glucocorticoid Receptor , Mitophagy , IL Receptor , Annexin A , NOS , Antibacterial , Autophagy |
Dexamethasone acetate (NSC 39471) is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexa... | |||
T4602 | Hydrocortisone hemisuccinate | Hydrocortisone 21-he,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate | Glucocorticoid Receptor , Others , Interleukin |
Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) is a corticosteroid used as an analytical and chromatography reagent. | |||
TQ0126 | Mirodenafil dihydrochloride | SK-3530 dihydrochloride | PDE |
Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction. | |||
T15102 | Dexamethasone palmitate | DXP | Glucocorticoid Receptor |
Dexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone, shows a 47-fold lower affinity for the glucocorticoid receptor than Dexamethasone. Dexamethasone palmitate is a glucocorticoid receptor agonist and an... | |||
T34383 | Rofleponide | Glucocorticoid Receptor | |
Rofleponide is a synthetic glucocorticosteroid with a high affinity for the rat thymus glucocorticoid receptor. | |||
T0270 | Hydrocortisone 17-butyrate | Cortisol 17-butyrate,Hydrocortisone butyrate | Glucocorticoid Receptor , Annexin A , Adrenergic Receptor |
Hydrocortisone 17-butyrate (Cortisol 17-butyrate) is a synthetic glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects. |
Cat No. | Product Name | Synonyms | Targets |
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T1560 | Prednisolone | Predonine,Hydroretrocortine,Metacortandralone | Glucocorticoid Receptor , Endogenous Metabolite |
Prednisolone (Hydroretrocortine) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. | |||
T1614 | Hydrocortisone | Cortisol | Glucocorticoid Receptor , Endogenous Metabolite |
Hydrocortisone (Cortisol) is a glucocorticoid hormone secreted by the adrenocortex. Hydrocortisone agonizes the glucocorticoid receptor, which promotes proteolytic metabolism, gluconeogenesis, capillary wall stabilizatio... | |||
T1168 | Desonide | Tridesilon,Locapred,Prednacinolone | Glucocorticoid Receptor |
Desonide (Prednacinolone) is a synthetic glucocorticosteroid for topical use, with anti-inflammatory activity. Desonide binds to glucocorticoid receptors in the cytoplasm, and the ligand-receptor complex is translocated ... | |||
T0798 | Triamcinolone | Fluoxyprednisolone,Aristocort,Rodinolone | Glucocorticoid Receptor , COX |
Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, triamcinolone binds to and activates the glucocorticoid receptor, which leads to transloca... | |||
T2810 | (20S)-Protopanaxatriol | 20(S)-APPT,g-PPT | Apoptosis , Estrogen Receptor/ERR , Glucocorticoid Receptor , Estrogen/progestogen Receptor , Liver X Receptor |
(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid receptor. | |||
T2884 | Cortisone | Kendall's compound E,17-Hydroxy-11-dehydrocorticosterone | Glucocorticoid Receptor , Endogenous Metabolite |
Cortisone (17-Hydroxy-11-dehydrocorticosterone) is a corticosteroid with potent glucocorticoid activity. | |||
T0034 | Cortisone acetate | Cortisone 21-acetate,NSC 49420 | Glucocorticoid Receptor , Endogenous Metabolite |
Cortisone Acetate is a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties. Cortisone acetate (NSC-49420) d... | |||
T1261 | Medroxyprogesterone Acetate | Medroxyprogesterone 17-acetate,Provera,Metigestrona,NSC-26386,Farlutin,Medroxyprogesterone (acetate) | Glucocorticoid Receptor , Estrogen/progestogen Receptor , Progesterone Receptor , Androgen Receptor , Endogenous Metabolite |
Medroxyprogesterone Acetate (Farlutin) is a synthetic progestin that is derived from 17-hydroxyprogesterone. It is a long-acting contraceptive that is effective both orally or by intramuscular injection and has also been... | |||
T1243 | Hydrocortisone acetate | Cortisol 21-acetate,Hydrocortisone 21-acetate | Glucocorticoid Receptor , Annexin A , Endogenous Metabolite |
Hydrocortisone acetate (Cortisol 21-acetate) is the synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties. | |||
T2748 | Cortodoxone | 11-Deoxycortisol,cortexolone,17α,21-dihydroxyprogesterone,Reichstein's substance S,11-Desoxycortisol | Glucocorticoid Receptor , Endogenous Metabolite |
Cortodoxone (11-Desoxycortisol) is a glucocorticoid steroid hormone that is an intermediate in the biosynthesis of cortisol in the adrenal gland. | |||
T0948L | Corticosterone | 17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,Corticosterone (From plants) | Glucocorticoid Receptor , Endogenous Metabolite |
Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active. Corticosterone is involved in the regulation of energy, immune responses, and stres... | |||
T1683 | Actriol | Epiestriol | Glucocorticoid Receptor |
Actriol (Epiestriol) is always used as Glucocorticoid Receptor agonist. | |||
T6343 | Geldanamycin | NSC 122750 | HSP , Influenza Virus , Tyrosine Kinases , Antibacterial , Antibiotic |
Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association. | |||
T1429 | 17α-Hydroxyprogesterone | Hydroxyprogesterone,17-OHP,17-Hydroxyprogesterone | Estrogen/progestogen Receptor , Progesterone Receptor , Endogenous Metabolite |
17α-Hydroxyprogesterone (17-OHP) is a physiological progestin that is produced during glucocorticoid and steroid hormone synthesis and is increased during the third trimester of pregnancy. Hydroxyprogesterone binds to th... | |||
TN3537 | Braylin | IL Receptor , TNF , NF-κB | |
Braylin has anti-inflammatory, antinociceptive and immunomodulatory effects, which possibly act through the glucocorticoid receptor activation and by inhibition of the transcriptional activity of NF-κB. Braylin is also ... |
Cat No. | Product Name | Species | Expression System |
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TMPY-06836 | NR3C1 Protein, Human, Recombinant (His) | Human | E. coli |
NR3C1 (Nuclear Receptor Subfamily 3 Group C Member 1) is a Protein Coding gene. This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements ... | |||
TMPJ-00110 | GITR/TNFRSF18 Protein, Mouse, Recombinant (hFc & His) | Mouse | Human Cells |
Tumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA、isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The p... | |||
TMPY-01117 | MRAP Protein, Human, Recombinant (hFc) | Human | HEK293 |
MRAP (Melanocortin 2 Receptor Accessory Protein) is a Protein Coding gene. This gene encodes a melanocortin receptor-interacting protein. It belongs to the MRAP family. MRAP, which contains a single transmembrane domain,... | |||
TMPH-00844 | HSD11B2 Protein, Human, Recombinant (His) | Human | Yeast |
Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids. | |||
TMPK-00132 | GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His & Avi), Biotinylated | Human | HEK293 |
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involv... | |||
TMPK-00133 | GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His) | Human | HEK293 |
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involv... | |||
TMPY-03259 | Calreticulin Protein, Human, Recombinant (His) | Human | HEK293 |
Calreticulin is a multifunctional protein. It acts as a main Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. Calreticulin binds Ca2+ ions (a second messenger in signal transduction), rendering... | |||
TMPK-01086 | GITR/TNFRSF18 Protein, Mouse, Recombinant (aa 22-153, His) | Mouse | HEK293 |
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involv... | |||
TMPK-01260 | GITR/TNFRSF18 Protein, Cynomolgus, Recombinant (aa 20-156, His) | Cynomolgus | HEK293 |
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involv... | |||
TMPY-03258 | Calreticulin Protein, Human, Recombinant (hFc) | Human | HEK293 |
Calreticulin is a multifunctional protein. It acts as a main Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. Calreticulin binds Ca2+ ions (a second messenger in signal transduction), rendering... | |||
TMPY-06327 | Calreticulin Protein, Human, Recombinant | Human | HEK293 |
Calreticulin is a multifunctional protein. It acts as a main Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. Calreticulin binds Ca2+ ions (a second messenger in signal transduction), rendering... | |||
TMPY-01383 | PRMT6 Protein, Human, Recombinant (His & Flag) | Human | HEK293 |
Protein arginine N-methyltransferase 6, also known as Histone-arginine N-methyltransferase PRMT6, PRMT6, and HRMT1L6, is a member of the protein arginine N-methyltransferase family and PRMT6 subfamily. PRMT6 is highly ex... |