T25131 |
AZD8309
|
333742-48-6
|
98%
|
|
AZD8309 is a potent, orally available antagonist of the chemokine receptor CXCR2 that regulates neutrophil transport, significantly reduces MPO in the pancreas a...
|
T38063L |
N-Acetyl lysyltyrosylcysteine amide acetate
|
|
98%
|
|
N-Acetyl lysyltyrosylcysteine amide acetate is an effective and selective tripeptide inhibitor of myeloperoxidase (MPO). N-Acetyl lysyltyrosylcysteine amide ace...
|
T22776 |
Ezatiostat hydrochloride
|
286942-97-0
|
98%
|
|
Ezatiostat hydrochloride is an effective inhibitor of glutathione S-transferase. Ezatiostat hydrochloride is a novel glutathione analog and the potential treatme...
|
T4313 |
Tinoridine hydrochloride
|
25913-34-2
|
98%
|
|
Tinoridine (Y-3642) is a non-steroidal anti-inflammatory drug. Tinoridine (5-100 μM), produced a concentration-dependent inhibition on the simultaneous increases...
|
TJS0338 |
4-Methylesculetin
|
529-84-0
|
98%
|
|
4-methylesculetin is one of the coumarin derivatives with great anti-oxidant and anti-inflammatory activities.
|
T3511 |
PF-1355
|
1435467-38-1
|
98%
|
|
PF-1355 is a selective 2-thiouracil mechanism-based MPO inhibitor. PF-1355 is used for treatment of vasculitic diseases.
|
T3646 |
RSL3
|
1219810-16-8
|
98%
|
|
RSL3 is a VDAC-independent ferroptosis activator with selectivity for tumor cells bearing oncogenic RAS. RSL3 is the inhibitor of the glutathione peroxidase 4, w...
|
T5463 |
Verdiperstat
|
890655-80-8
|
98%
|
|
Verdiperstat (AZD3241) is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and can be used in the research of neuro...
|
T5340 |
MPO-IN-28
|
37836-90-1
|
98%
|
|
MPO-IN-28 is a novel potent, irreversible Myeloperoxidase (MPO) inhibitor with IC50 of 44 nM.
|
T1258 |
Nabumetone
|
42924-53-8
|
98%
|
|
Nabumetone(BRL14777) is a non-steroidal anti-inflammatory drug and its active metabolite 6MNA inhibits the enzymes cyclo-oxygenase I and II.
|
T1659 |
Melatonin
|
73-31-4
|
98%
|
|
Melatonin is a biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and...
|
T11505 |
GSTO1-IN-1
|
568544-03-6
|
98%
|
|
GSTO1-IN-1 is a potent glutathione S-transferase omega 1 inhibitor (GSTO1; IC50: 31 nM).
|
T8970 |
ML162
|
1035072-16-2
|
98%
|
|
ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-typ...
|
T4090 |
PF-06282999
|
1435467-37-0
|
98%
|
|
PF-06282999 is a potent and selective myeloperoxidase inhibitor which is potentially useful for the treatment of cardiovascular diseases.
|
T0646 |
5-Aminosalicylic Acid
|
89-57-6
|
98%
|
|
Mesalamine is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the acti...
|
T8375 |
ML-210
|
1360705-96-9
|
98%
|
|
ML-210 is a selective RAS and covalent glutathione peroxidase 4 (GPX4) inhibitor(GPX4, EC50 : 30 nM), with anti-cancer activity
|
T12189 |
NBDHEX
|
787634-60-0
|
98%
|
|
NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1) .
|
T0133 |
Cefdinir
|
91832-40-5
|
98%
|
|
Cefdinir is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, proven effective for common bacterial infections of t...
|
T1296 |
4-Aminosalicylic acid
|
65-49-6
|
98%
|
|
Aminosalicylic Acid is an analog of para-aminobenzoic acid (PABA) with antitubercular activity.
|
T14379 |
AZD5904
|
618913-30-7
|
98%
|
|
AZD5904 is a potent and irreversible human Myeloperoxidase (MPO) inhibitor(IC50 of 140 nM and has similar potency in mouse and rat).
|