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Glutathione Peroxidase

Glutathione peroxidase (GPx) is the general name of an enzyme family with peroxidase activity whose main biological role is to protect the organism from oxidative damage. The biochemical function of glutathione peroxidase is to reduce lipid hydroperoxides to their corresponding alcohols and to reduce free hydrogen peroxide to water.
Cat No. product name
T38063L N-Acetyl lysyltyrosylcysteine amide acetate N-Acetyl lysyltyrosylcysteine amide acetate 是一种有效且特异性的髓过氧化物酶 (MPO) 三肽抑制剂。 N-Acetyl lysyltyrosylcysteine amide acetate 抑制 MPO 依赖性次氯酸的生成、蛋白质硝化和 LDL 氧化反应。 N-Acetyl ...
T1296 4-Aminosalicylic acid Aminosalicylic Acid is an analog of para-aminobenzoic acid (PABA) with antitubercular activity.
T0646 5-Aminosalicylic Acid Mesalamine is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the acti...
T12189 NBDHEX NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1) .
T3646 RSL3 RSL3 is a VDAC-independent ferroptosis activator with selectivity for tumor cells bearing oncogenic RAS. RSL3 is the inhibitor of the glutathione peroxidase 4, w...
T0133 Cefdinir Cefdinir is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, proven effective for common bacterial infections of t...
T5340 MPO-IN-28 MPO-IN-28 is a novel potent, irreversible Myeloperoxidase (MPO) inhibitor with IC50 of 44 nM.
T14379 AZD5904 AZD5904 is a potent and irreversible human Myeloperoxidase (MPO) inhibitor(IC50 of 140 nM and has similar potency in mouse and rat).
T8970 ML162 ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-typ...
T4313 Tinoridine hydrochloride Tinoridine (Y-3642) is a non-steroidal anti-inflammatory drug. Tinoridine (5-100 μM), produced a concentration-dependent inhibition on the simultaneous increases...
T11505 GSTO1-IN-1 GSTO1-IN-1 is a potent glutathione S-transferase omega 1 inhibitor (GSTO1; IC50: 31 nM).
T1659 Melatonin Melatonin is a biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and...
T22776 Ezatiostat hydrochloride Ezatiostat hydrochloride is an effective inhibitor of glutathione S-transferase. Ezatiostat hydrochloride is a novel glutathione analog and the potential treatme...
T5097 Ezatiostat Ezatiostat is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity.
T8375 ML-210 ML-210 is a selective RAS and covalent glutathione peroxidase 4 (GPX4) inhibitor(GPX4, EC50 : 30 nM), with anti-cancer activity
T1258 Nabumetone Nabumetone(BRL14777) is a non-steroidal anti-inflammatory drug and its active metabolite 6MNA inhibits the enzymes cyclo-oxygenase I and II.
TJS0338 4-Methylesculetin 4-methylesculetin is one of the coumarin derivatives with great anti-oxidant and anti-inflammatory activities.
T5463 Verdiperstat Verdiperstat (AZD3241) is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and can be used in the research of neuro...
T4090 PF-06282999 PF-06282999 is a potent and selective myeloperoxidase inhibitor which is potentially useful for the treatment of cardiovascular diseases.
T26389 4-POBN 4-POBN 是一种有效且不可逆的髓过氧化物酶抑制剂 (IC50 = 0.3 µM)。 4-POBN 可用于亚急性中风的研究。
N-Acetyl lysyltyrosylcysteine amide acetate
T38063L
N-Acetyl lysyltyrosylcysteine amide acetate 是一种有效且特异性的髓过氧化物酶 (MPO) 三肽抑制剂。 N-Acetyl lysyltyrosylcysteine amide acetate...
4-Aminosalicylic acid
T1296
Aminosalicylic Acid is an analog of para-aminobenzoic acid (PABA) with antitubercular activity.
5-Aminosalicylic Acid
T0646
Mesalamine is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the acti...
NBDHEX
T12189
NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1) .
RSL3
T3646
RSL3 is a VDAC-independent ferroptosis activator with selectivity for tumor cells bearing oncogenic RAS. RSL3 is the inhibitor of the glutathione peroxidase 4, w...
Cefdinir
T0133
Cefdinir is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, proven effective for common bacterial infections of t...
MPO-IN-28
T5340
MPO-IN-28 is a novel potent, irreversible Myeloperoxidase (MPO) inhibitor with IC50 of 44 nM.
AZD5904
T14379
AZD5904 is a potent and irreversible human Myeloperoxidase (MPO) inhibitor(IC50 of 140 nM and has similar potency in mouse and rat).
ML162
T8970
ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-typ...
Tinoridine hydrochloride
T4313
Tinoridine (Y-3642) is a non-steroidal anti-inflammatory drug. Tinoridine (5-100 μM), produced a concentration-dependent inhibition on the simultaneous increase...
GSTO1-IN-1
T11505
GSTO1-IN-1 is a potent glutathione S-transferase omega 1 inhibitor (GSTO1; IC50: 31 nM).
Melatonin
T1659
Melatonin is a biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and...
Ezatiostat hydrochloride
T22776
Ezatiostat hydrochloride is an effective inhibitor of glutathione S-transferase. Ezatiostat hydrochloride is a novel glutathione analog and the potential treatme...
Ezatiostat
T5097
Ezatiostat is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity.
ML-210
T8375
ML-210 is a selective RAS and covalent glutathione peroxidase 4 (GPX4) inhibitor(GPX4, EC50 : 30 nM), with anti-cancer activity
Nabumetone
T1258
Nabumetone(BRL14777) is a non-steroidal anti-inflammatory drug and its active metabolite 6MNA inhibits the enzymes cyclo-oxygenase I and II.
4-Methylesculetin
TJS0338
4-methylesculetin is one of the coumarin derivatives with great anti-oxidant and anti-inflammatory activities.
Verdiperstat
T5463
Verdiperstat (AZD3241) is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and can be used in the research of neuro...
PF-06282999
T4090
PF-06282999 is a potent and selective myeloperoxidase inhibitor which is potentially useful for the treatment of cardiovascular diseases.
4-POBN
T26389
4-POBN 是一种有效且不可逆的髓过氧化物酶抑制剂 (IC50 = 0.3 µM)。 4-POBN 可用于亚急性中风的研究。