HCV Protease

NS2-3 protease (of hepatitis C virus, HCV) is an enzyme responsible for proteolytic cleavage between NS2 and NS3, which are non-structural proteins that form part of the HCV virus particle. NS3 protease of hepatitis C virus, on the other hand, is responsible for the cleavage of non-structural protein downstream. Both of these proteases are directly involved in HCV genome replication, that is, during the viral life-cycle that leads to virus multiplication in the host that has been infected by the virus.

Cat. No.	Product name	CAS No.	Purity
TQ0030	Tomeglovir	233254-24-5	98%
TQ0030	Tomeglovir is a potent anti-CMV agent, inhibiting the processing of viral DNA-concatemers (IC50s: 0.34/0.039 μM for HCMV and MCMV).
T71653	GS-9256	1001094-46-7	98%
T71653	GS-9256 is a selective inhibitor of the HCV NS3 protease, exhibiting favorable pharmacokinetic properties and antiviral activity [1].
T14095	ACH-806	870142-71-5	98%
T14095	ACH-806 is an NS4A antagonist. It can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM.
TN1703	Glycyrin	66056-18-6	98%
TN1703	Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice.
T12964	Sofosbuvir impurity I	T12964	98%
T12964	Sofosbuvir impurity I is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T12956	Sofosbuvir impurity A	1496552-16-9	98%
T12956	Sofosbuvir impurity A is an diastereoisomer of Sofosbuvir. Sofosbuvir is anHCV RNA replication inhibitor ,with potent anti-hepatitis C virus activity.
TN4404	Ladanein	10176-71-3	98%
TN4404	Ladanein is a phytochemicals inhibitor that is known to disrupt the interactions of core and other hepatitis C virus (HCV) proteins.Ladanein possesses free radic...
T14555	BI-1230	849022-32-8	98%
T14555	BI-1230 is a potent inhibitor of HCV NS3 protease, exhibiting efficacy in the low nanomolar range, and notably suppresses viral replication. This compound demons...
TN6732	Oenothein B	104987-36-2	98%
TN6732	Oenothein B is a specific inhibitor of poly(ADP-ribose) glycohydrolase. Oenothein B shows antioxidant, anti-inflammatory, antifungal, anti-HCV, and antitumor pro...
T16774	RO-9187	876708-03-1	98%
T16774	RO-9187 is an effective HCV virus replication inhibitor(IC50: 171 nM).
T1188	Mizoribine	50924-49-7	99.98%
T1188	Mizoribine (NSC-289637) belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.
T1565	Deferiprone	30652-11-0	99.97%
T1565	Deferiprone (Deferidone) is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.
T5S1598	Mulberroside C	102841-43-0	99.97%
T5S1598	1. Mulberroside C has antioxidant activity.
T9577	HCV-IN-31	1998705-62-6	99.95%
T9577	HCV-IN-31 is a HCV inhibitor with an EC50/EC95 of 15.7 μM.
T22489	2'-MeCCPA	205171-12-6	99.93%
T22489	2'-MeCCPA is a potent and highly selective A1 adenosine receptor (A1AR) agonist with a K-value of 1.8 nM for AR.2'-MeCCPA inhibits trichostatin-stimulated adenyl...
T6846	Vesatolimod	1228585-88-3	99.92%
T6846	Vesatolimod (GS-9620) is an effective and specific orally active agonist of Toll-like receptor 7.
T4474	Asunaprevir	630420-16-5	99.92%
T4474	Asunaprevir (BMS-650032) is an effective hepatitis C virus (HCV) NS3 protease inhibitor.
T1822L	Clemizole hydrochloride	1163-36-6	99.91%
T1822L	Clemizole hydrochloride is an antagonist for H1 histamine receptor. According to the research, Clemizole hydrochloride can inhibit hepatitis C virus (HCV) replic...
T3334	Velpatasvir	1377049-84-7	99.91%
T3334	Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor. GS-5816 has demonstrated pan-genotypic activity and a h...
T3810	Saikosaponin B2	58316-41-9	99.88%
T3810	Saikosaponin B2 acts on HCV E2 and inhibits infection by several genotypic strains and prevents binding of serum-derived HCV onto hepatoma cells. Saikosaponin B2...