T3753 |
Sinapinic Acid
|
530-59-6
|
99.92%
|
|
Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p6...
|
T60616 |
MPT0G211
|
2151853-97-1
|
99.91%
|
|
MPT0G211 is a highly selective and orally active HDAC6 inhibitor (IC50=0.291 nM) that has neuroprotective effects and has shown anti-metastatic activity in human...
|
T6980 |
Scriptaid
|
287383-59-9
|
99.91%
|
|
Scriptaid (GCK1026) is an inhibitor of HDAC, and has a greater effect on acetylated H4 than H3.
|
T6474 |
Divalproex Sodium
|
76584-70-8
|
99.84%
|
|
Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by incr...
|
T7082 |
HDAC8-IN-1
|
1417997-93-3
|
99.83%
|
|
MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cance...
|
T4389 |
SR-4370
|
1816294-67-3
|
99.82%
|
|
SR-4370 is an HDAC inhibitor. SR- 4370 exhibited IC50 values of 0.5 μM, 0.1 μM and 0.06 μM towards HDAC1, HDAC2 and HDAC3, resp.
|
T3358 |
ITSA-1
|
200626-61-5
|
99.82%
|
|
ITSA-1 is membrane permeable and specifically suppresses TSA inhibition of HDAC (histone deacetylase), but shows no activity towards other HDAC inhibitors.
|
TQ0207 |
Sulforaphane
|
4478-93-7
|
99.79%
|
|
Sulforaphane is derived from the consumption of cruciferous vegetables, such as broccoli. It has shown anticancer and cardioprotective activities.
|
T1083L |
Theophylline monohydrate
|
5967-84-0
|
99.79%
|
|
Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distributio...
|
T4370 |
Resminostat hydrochloride
|
1187075-34-8
|
99.78%
|
|
Resminostat hydrochloride (RAS2410 hydrochloride) is an effective inhibitor of HDAC1/HDAC3/HDAC6 (IC50: 42.5/50.1/71.8 nM), respectively, and shows less potent a...
|
T10883L |
CRA-026440 hydrochloride
|
847459-98-7
|
99.78%
|
|
CRA-026440 hydrochloride is a potent and broad-spectrum HDAC inhibitor. CRA-026440 hydrochloride exhibits Ki values against recombinant HDAC isoenzymes HDAC1, HD...
|
T1762 |
RGFP966
|
1357389-11-7
|
99.77%
|
|
RGFP966 is an HDAC3 inhibitor (IC50: 0.08 μM) and does not affect other HDACs at concentrations up to 15 µM.
|
T2454 |
Dacinostat
|
404951-53-7
|
99.77%
|
|
LAQ824 (Dacinostat (NVP-LAQ824)) is a novel HDAC inhibitor with IC50 of 32 nM and is an activator of the p21 promoter.
|
T6481 |
Droxinostat
|
99873-43-5
|
99.76%
|
|
Droxinostat (NS 41080) is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3 a...
|
T5886 |
4-Phenylbutyric acid
|
1821-12-1
|
99.76%
|
|
4-Phenylbutyric acid (Benzenebutyric acid) is an inhibitor of HDAC,and is an antineoplastic agent.
|
T3937 |
Methyl L-histidinate dihydrochloride
|
7389-87-9
|
99.74%
|
|
The inhibitory effect of Methyl L-histidinate dihydrochloride (L-Histidine methyl ester dihydrochloride) on histidine decarboxylase in Sprague-Dawley rat stomach...
|
T3199 |
PTACH
|
848354-66-5
|
99.74%
|
|
PTACH (Cpd 51) (NCH-51) is a SAHA-based inhibitor of human HDAC. It can potently inhibit the growth of various human Y cells (EC50: 1 to 10 μM).
|
T2430 |
HPOB
|
1429651-50-2
|
99.72%
|
|
HPOB is an effective and specific HDAC6 inhibitor (IC50: 56 nM), >30-fold selectivity over other HDACs.
|
T37067 |
9-hydroxy Stearic Acid
|
3384-24-5
|
99.7%
|
|
9-hydroxy Stearic Acid is a hydroxy fatty acid that is the active metabolite of 9-PAHSA. 9-hydroxy Stearic Acid is formed from 9-PAHSA through carboxyl ester lip...
|
T25175 |
BRD 9757
|
1423058-85-8
|
99.69%
|
|
BRD 9757 (N-Hydroxy-1-cyclopentene-1-carboxamide) is a selective inhibitor of HDAC6 (IC50 = 30 nM).
|