T0100 |
Atazanavir sulfate |
Atazanavir sulfate is an azapeptide and HIV-PROTEASE INHIBITOR that is used in the treatment of HIV INFECTIONS and AIDS in combination with other ANTI-HIV AGENT...
|
T0100L |
Atazanavir |
Atazanavir(BMS-232632) is an highly effective HIV-1 protease inhibitor. |
T0110 |
Zalcitabine |
Zalcitabine(Dideoxycytidine;ddC; 2',3'-Dideoxycytidine) is a nucleoside analog reverse transcriptase inhibitor (NRTI); At low concentrations, It can potently in...
|
T10111 |
3-Deazaadenosine hydrochloride |
3-Deazaadenosine hydrochloride is an inhibitor of S-adenosylhomocysteine hydrolase (Ki: 3.9 µM). It has anti-inflammatory, anti-proliferative, and anti-HIV act...
|
T10111L |
3-Deazaadenosine |
3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 µM, and it has anti-inflammatory, anti-proliferative and anti-HIV activi...
|
T10296 |
Mavorixafor trihydrochloride |
Mavorixafor trihydrochloride is a selective and orally available CXCR4 antagonist (IC50: 13 nM against CXCR4 125I-SDF binding) and also inhibits the replication...
|
T10570 |
Fostemsavir Tris |
Fostemsavir Tris is the prodrug of BMS-626529. Fostemsavir Tris is an attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells. |
T10658 |
CA inhibitor 1 |
CA inhibitor 1 (GS-6207 analog) is a potent inhibitor of the HIV capsid. |
T10714 |
CCR5 antagonist 1 |
CCR5 antagonist 1 is a CCR5 antagonist extracted from WO 2004054974 A2. It can inhibit HIV replication. |
T10928 |
Cytochalasin A |
Cytochalasin A is a cell-permeable fungal toxin and is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC50 = 3 μM)...
|
T11189 |
Emtricitabine S-oxide |
Emtricitabine is a potent nucleoside reverse transcriptase inhibitor used for the treatment of HIV infection.Emtricitabine S-oxide (Emtricitabine sulfoxide) is ...
|
T12420 |
Pentosan Polysulfate |
Pentosan Polysulfate is a potent and selective anti-HIV agent.with anti-inflammatory and pro-chondrogenic properties,and used for treatment of interstitial cyst...
|
T12420L |
Pentosan Polysulfate Sodium |
Pentosan Polysulfate Sodium is a potent and selective anti-HIV agent.with anti-inflammatory and pro-chondrogenic properties,and used for treatment of interstiti...
|
T1267 |
Abacavir |
Abacavir is a nucleoside reverse transcriptase inhibitor analog of guanosine. This agent decreases HIV viral loads, retards or prevents the damage to the immune...
|
T12715 |
Reverse transcriptase-IN-1 |
Reverse transcriptase-IN-1 is a diarylbenzopyrimidine (DABP) analogue and a potent, orally active HIV-1 nonnucleoside reverse transcriptase inhibitor. |
T12953 |
Sodium copper chlorophyllin B |
Sodium copper chlorophyllin B exerts antiviral activities against Influenza virus and HIV (IC50s of 50 to 100 μM). |
T13796 |
Nigranoic acid |
Nigranoic acid is a natural product,and inhibits HIV-1 reverse transcriptase. |
T14208 |
AMD 3465 |
AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM). However, it has no effect on CCR5-using (R5) viruses. AMD 3465 (GENZ-644494) ...
|
T14307 |
Aplaviroc |
Aplaviroc (AK 602), a SDP derivative, is a CCR5 antagonist. With IC50s of 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL and HIV-1MOKW. |
T14313 |
Apricitabine |
Apricitabine (SPD754; AVX754) shows promising antiretroviral efficacy, good tolerability and a low propensity for resistance selection in antiretroviral-naive H...
|
T14488 |
Azt-pmap |
Azt-pmap shows anti-HIV activity[1]. Azt-pmap, a nucleoside analogue, is an aryl phosphate derivative of AZT. AZT is a nucleoside reverse transcriptase inhibito...
|
T14559 |
BI 224436 |
BI 224436 is an inhibitor of HIV-1 noncatalytic site integrase. With EC50 values of less than 15 nM against different HIV-1 laboratory strains. |
T14831 |
Bryostatin 1 |
Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a CNS)permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domai...
|
T15210 |
Elsulfavirine |
Elsulfavirine is an HIV-1 infection reverse transcriptase inhibitor. It is a new anti-HIV drug. |
T1525 |
Ritonavir |
Ritonavir is a peptidomimetic agent that inhibits both HIV-1 and HIV-2 proteases. Ritonavir is highly inhibited by serum proteins but boosts the effect of other...
|
T15371 |
Gardiquimod |
Gardiquimod is a TLR7/8 agonist. When used at concentrations below 10 μM, Gardiquimod specifically activates TLR7. Gardiquimod could inhibit HIV-1 infection ...
|
T15683 |
L-689502 |
L-689502 is a potent HIV-l protease inhibitor (IC50: 1 nM). |
T1595 |
Nevirapine |
Nevirapine is a benzodiazepine non-nucleoside reverse transcriptase inhibitor. In combination with other antiretroviral drugs, nevirapine reduces HIV viral load...
|
T16096 |
Filorexant |
Filorexant is an orally bioavailable effective and selective reversible OX1 and OX2 receptor antagonist (<3 nM in binding). |
T16112 |
ML67-33 |
ML67-33 rapidly and reversibly affects K2P2.1 (TREK-1) (EC50s: 36.3 μM and 9.7 μM in cell-free and HEK293 cells, respectively). ML67-33 is a selective activat...
|
T1623 |
Lopinavir |
Lopinavir is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation. Lopinavir is less affected by binding ...
|
T16500 |
PF-3450074 |
PF-3450074 acts at an early stage of HIV-1 infection inhibits viral replication by directly competing with the binding of CPSF6 (nuclear host factors cleavage a...
|
T16548 |
PKF050-638 |
PKF050-638 inhibits the CRM1-mediated Rev nuclear export by disrupting CRM1-NES interaction. PKF050-638 is an effective and selective inhibitor of HIV-1 Rev (IC...
|
T16555 |
PNU-103017 |
PNU-103017 is an inhibitor of HIV protease. |
T16829 |
(S)-BI-1001 |
(S)-BI-1001 is an active S-enantiomer of BI-1001. (S)-BI-1001 has antiviral potency against HIV-1 integrase (IC50: 28 nM, and EC50: 450 nM and a Kd: 4.7 μM). |
T16973 |
TAK-220 |
TAK-220 is a selective and orally bioavailable CCR5 antagonist (IC50s: 3.5 nM and 1.4 nM for inhibition on the binding of RANTES and MIP-1α to CCR5, respective...
|
T1815 |
Dapivirine |
Dapivirine is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. |
T1883 |
Des(benzylpyridyl) Atazanavi |
Atazanavir is a highly effective HIV-1 protease inhibitor. |
T2239 |
Raltegravir potassium |
Raltegravir potassium salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection. |
T2324 |
Darunavir |
Darunavir is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alo...
|
T2329 |
Dolutegravir sodium |
Dolutegravir sodium salt(DTG; GSK1349572) is an HIV integrase inhibitor(IC50: 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q1...
|
T2332 |
Elvitegravir |
Elvitegravir is a Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor. The mechanism of action of elvitegravir is as an HIV Integrase Inhibitor, an...
|
T2393 |
Efavirenz |
Efavirenz is a Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of efavirenz is as a Non-Nucleoside...
|
T2409L |
Tenofovir Disoproxil Fumarate |
Tenofovir Disoproxil Fumarate is a pro-drug, fumaric acid salt form of tenofovir, a nucleoside reverse transcriptase inhibitor analog of adenosine. Tenofovir di...
|
T2728 |
Limonin |
Limonin is a triterpenoid enriched in citrus fruits, which has antivirus and antitumor ability. |
T2830 |
Betulinic acid |
Betulinic acid is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has antiretro...
|
T2S0223 |
Isosinensetin |
1. Isosinensetin shows antioxidant and HIV-1 protease inhibiting activities. |
T2S0605 |
Liquidambaric lactone |
Liquidambaric lactone may have inhibitory HIV-1 reverse transcriptase activity. |
T3172 |
Trovirdine |
Trovirdine is a thiourea non-nucleoside reverse transcriptase inhibitor. |
T3335 |
Darunavir Ethanolate |
Darunavir ethanolate is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE wh...
|
T3523 |
Fostemsavir |
BMS-663068 is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection. |
T3632 |
Doravirine |
Doravirine is a non-nucleoside reverse transcriptase inhibitor, used in the treatment of HIV/AIDS. |
T3683 |
lithospermic acid |
lithospermic acid is a potent anti-HIV agent and shows anti-gonadotrophic and anti-thyroidal effects. |
T3732 |
Sebacic acid |
Sebacic acid is a saturated, straight-chain naturally occurring dicarboxylic acid. |
T3S2007 |
MRE-269 |
Ursonic acid belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton. It has potential as HIV-1 Protease Inhibit...
|
T4493 |
Bictegravir |
Bictegravir is a potent inhibitor of HIV-1 integrase (IC50: 7.5 nM). |
T4537 |
SodiumCholate |
SodiumCholate exhibits a strong spermicidal and antiviral [anti-human immunodeficiency virus (HIV)-1] activity. |
T4962 |
Ginsenoside Z-R1 |
Zingibroside R1 has anti-HIV-1 activity. |
T4S0295 |
Cosmosiin |
1. Cosmosiin is a anti-HIV agent. 2. Cosmosiin may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylati...
|
T4S1383 |
Escin IA;Aescin IA |
Escin IA is a triterpene saponin isolated from horse chestnut, which inhibits HIV-1 protease with IC50 values of 35 μM. Escin IA has anti-TNBC metastasis activ...
|
T4S1718 |
Punicalin |
Punicalin exerts anti-inflammatory, antioxidative, and anti-hepatotoxic activities, it shows inhibitory activity on HIV-1 reverse transcriptase in a dose-depend...
|
T4S1999 |
Valepotriate |
Valepotriate fraction can have sedative effects and affect behavioral parameters related to recognition memory. Valepotriates, a new class of cytotoxic and anti...
|
T5782 |
Bevirimat |
Bevirimat(PA-457) is a first-in-class inhibitor of HIV-1 maturation, blocking the cleavage of the Gag capsid (CA) precursor, CA-SPI, to mature CA protein during...
|
T5863 |
Indinavir sulfate |
Indinavir is a HIV protease inhibitor.It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM. |
T5965 |
Ditiocarb sodium |
Ditiocarb sodium (Sodium diethyldithiocarbamate) is an accelerator of the rate of copper cementation. Sodium diethyldithiocarbamate reduces the incidence of HIV...
|
T6001 |
Nelfinavir Mesylate |
Nelfinavir Mesylate is an effective HIV protease inhibitor (Ki: 2 nM). |
T6065 |
Triciribine |
Triciribine is a DNA synthesis inhibitor, and it also inhibits Akt and HIV-1/2. |
T6098 |
Cabotegravir |
Cabotegravir (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (IC50: 3.0 nM). |
T6198 |
Dolutegravir |
Dolutegravir (IC50=2.7 nM), a two-metal-binding HIV integrase inhibitor, exhibits medium activity against raltegravir-resistant signature mutants Y143R, Q148K, ...
|
T6256 |
YYA-021 |
YYA-021 inhibits HIV entry, with high anti-HIV activity and low cytotoxicity. |
T6367 |
Abacavir sulfate |
Abacavir, a nucleoside analogue,effectively utilize its antiviral activity |
T6388 |
Amprenavir |
Amprenavir is a synthetic derivative of hydroxyethylamine sulfonamide that selectively binds to and inhibits human immunodeficiency virus (HIV) protease. |
T6420 |
BMS-707035 |
BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2. |
T6653 |
Salmeterol Xinafoate |
Salmeterol Xinafoate is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstr...
|
T7111 |
Tenofovir Disoproxil |
Tenofovir Disoproxil is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. |
T7212 |
Delavirdine (mesylate) |
Delavirdine (mesylate) is a non-nucleoside reverse transcriptase inhibitor (NNRTI). |
T7282 |
Tenofovir alafenamide fumarate |
Tenofovir alafenamide fumarate (TAF) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir (TFV) |
T7382 |
NBD-557 |
NBD-557 is a potentially HIV-1 inhibitor. |
T7455 |
4-Chloro-2-(trifluoroacetyl)aniline hydrochloride |
4-Chloro-2-(trifluoroacetyl)aniline hydrochloride is an inhibitor of HIV-1 RT (HIV reverse transcriptase) . |
T7700 |
Lersivirine(UK 453061) |
Lersivirine(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy. |
T7779 |
Nelfinavir |
Nelfinavir is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV) (Ki=2 nM). Nelfinavir is a broad-spectrum, anticancer agen...
|
T7789 |
DRB |
DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II (IC50 range of 4-10 µM) |
T7903 |
Saquinavir |
Saquinavir is a potent HIV protease inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS. |
T8156 |
Saquinavir mesylate |
Saquinavir mesylate is an Inhibitor of HIV Proteaseused in antiretroviral therapy |
T8238 |
Fosamprenavir Calcium Salt |
Fosamprenavir Calcium Salt (GW433908G) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility[1]. Anti-HIV i...
|
T8311 |
ABX-464 |
ABX-464 is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs) (IC50 : 0.1 μM - 0.5 μM) |
T8689 |
CHLOROQUINE |
Chloroquine is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine is an antimalarial and anti-inflammatory agent widely used to treat malaria an...
|
TL0006 |
Chicoric Acid |
Chicoric Acid is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. It also a class of cannabinomimetic...
|
TMA1012 |
Ganoderiol F |
Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency vir...
|
TN1047 |
Ingenol mebutate |
Ingenol mebutate shows anticancer activity, and P-gp-mediated absorptive transport, dermal penetration, and vascular damage contribute to the anticancer activit...
|
TN1194 |
16beta,17-Dihydroxy-ent-kaurane-19-oic acid |
16beta,17-Dihydroxy-ent-kaurane-19-oic acid as an anti-HIV principle, it showed significant activity against HIV replication in H9 lymphocyte cells with an EC50...
|
TN1235 |
3,4,5-Tricaffeoylquinic acid |
3,4,5-Tricaffeoylquinic acid may attenuate the TNF-α±- and LPS-stimulated production of inflammatory mediators in keratinocytes by suppressing the Toll-like r...
|
TN1302 |
6,8-Diprenylorobol |
6,8-Diprenylorobol possesses weaker anti-H. pylori activity, it may be a useful chemopreventive agent for peptic ulcer or gastric cancer in H. pylori-infected i...
|
TN1348 |
8-Prenylluteone |
8-Prenylluteone can potently inhibit HIV-1 PR activity. |
TN1587 |
Dihydroseselin |
Dihydroseselin type of pyranocoumarin possessing a 4'-isovaleryl group is important to suksdorfin's enhanced anti-HIV activity. |
TN1670 |
Ganodermanondiol |
Ganodermanondiol exhibits potent cytoprotective effects on t-BHP-induced hepatotoxicity in human liver-derived HepG2 cells, presumably through Nrf2-mediated ant...
|
TN1708 |
Gomisin M2 |
Gomisin M2 is an anti-HIV agent. |
TN1727 |
Helichrysetin |
Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four select...
|
TN1767 |
Interiotherin A |
Interiotherin A inhibits HIV replication with the EC50 value of 3.1 micrograms/mL. |
TN1852 |
Lancifodilactone F |
Lancifodilactone F exerts minimal cytotoxicity against C8166 cells (CC50 > 200 microg/mL) and shows anti-HIV activity with EC50 = 20.69 +/- 3.31 microg/mL and a...
|
TN1866 |
Licoricesaponin G2 |
Licoricesaponin G2 has the anti-inflammatory effects as NF-κB inhibitors, it has anti-HIV activity via significantly interacted with R15K. |
TN2097 |
Pomolic acid |
Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities, it can induce apoptosis in SK-OV-3 cells, which is mediated by the mitochondrial-media...
|
TN2158 |
Robinetin |
Robinetin has antioxidant and antiradical activities, inhibits EYPC membrane lipid peroxidation and HbA glycosylation with high efficiency. |
TN2186 |
Schisantherin D |
Schisantherin D shows good anti-HIV activity with the EC50 value of 0.5 micrograms/mL, and the therapeutic index (TI) value of 110. |
TN2231 |
Soyasaponin II |
Soyasaponin II has antiviral effects, it can inhibit the replication of human cytomegalovirus, influenza virus, and human immunodeficiency virus type 1. |
TN2283 |
Tripterifordin |
Tripterifordin shows anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 1 microgram/ml. |
TN2284 |
Triptonine B |
Triptonine B demonstrates potent anti-HIV activity with an EC(50) value of <0.10 microg/mL and an in vitro therapeutic index value of >1000. |
TN2839 |
2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid |
2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid has anti-HIV activity. It shows an inhibitory effect on the activation of Epstein-Barr virus early antigen ...
|
TN3119 |
5-Hydroxy-7,8-dimethoxyflavanone |
5-Hydroxy-7,8-dimethoxyflavanone shows anti-inflammatory activity, it can significantly decrease TNF-alpha, IL-6, macrophage inflammatory protein-2 (MIP-2), and...
|
TN3152 |
6-Acetonyldihydrochelerythrine |
6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therap...
|
TN3444 |
Aristolactam BII |
Aristolactam BII exhibits antimicrobial and antiinflammatory activity, it shows significant activity towards DPPH radical scavenging and potent inhibitory effec...
|
TN3567 |
Calanolide E |
Calanolide E2 has anti-HIV activity. |
TN3704 |
Coronalolide |
Coronalolide shows significant cytotoxic activities in P-388 cell line, it also displays significant anti-HIV activities in the HIV-1RT assay. Coronalolide and ...
|
TN3705 |
Coronalolide methyl ester |
Coronalolide methyl ester displays significant anti-HIV activities in the HIV-1RT assay. It and coronalolide show broad cytotoxic activity against a panel of hu...
|
TN3777 |
Daurichromenic acid |
Daurichromenic acid is a terpenophenol with a potent anti-HIV activity. |
TN4109 |
Ganolucidic acid A |
Ganolucidic acid A exhibits cytotoxicity, has inhibitory activities against human HeLa cervical cancer cell lines. It shows significant anti-human immunodeficie...
|
TN4264 |
Isoapetalic acid |
Isoapetalic acid and apetalic acid exhibit cytotoxic activities towards both cancer cell lines(human breast cancer (MCF-7) and human lung carcinoma (A-549) cell...
|
TN4347 |
Jacoumaric acid |
Jacoumaric acid is a lead molecule from the library or database of natural compounds as a HIV-1 protease inhibitor. |
TN4433 |
Licoarylcoumarin |
Licoarylcoumarin is a strong inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. Licoarylcoumarin has antibacterial effects on the VRE s...
|
TN4539 |
Methyl chanofruticosinate |
Methyl chanofruticosinate has weak anti-HIV-1 activity. |
TN4555 |
Methyl salvionolate A |
Methyl salvionolate A has anti-HIV-1 activity. |
TN4584 |
Morolic acid |
Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent chang...
|
TN4585 |
Moronic acid |
Moronic acid shows oral therapeutic efficacy in HSV-infected mice and possessed novel anti-HSV activity. It also shows significant anti-HIV activity (EC(50) 186...
|
TN4605 |
Myriceric acid B |
Myriceric acid B is a potent HIV-1 entry inhibitor targeting gp41 and can serve as a lead compound for developing novel anti-HIV-1 drug. Myriceric acid B scaven...
|
TN4646 |
Neotripterifordin |
Neotripterifordin shows potent anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 25 nM and TI of 125. |
TN4673 |
(+)-Nortrachelogenin |
(+)-Nortrachelogenin is moderately active against HIV-1 in vitro; it also can induce morphological deformation of P. oryzae mycelia with the MMDC value of 31.3 ...
|
TN4675 |
Nortrachelogenin |
Nortrachelogenin is a novel agent for prostate cancer therapy with ability to inhibit Akt membrane localization and activity as well as the activation of growth...
|
TN4820 |
Pre-schisanartanin B |
Pre-schisanartanin B has cytotoxicity, it also has anti-HIV-1 activity. |
TN4835 |
Przewalskin |
Przewalskin A and Przewalskin B showed modest anti-HIV-1 activity with EC50 = 41 and 30 microg/mL, respectively. |
TN4911 |
Rhuscholide A |
Rhuscholide A possesses significant anti-HIV-1 activity with an EC50 value of 1.62 microM and a therapeutic index (TI) of 42.40. |
TN4934 |
Salaspermic acid |
Salaspermic acid is an inhibitor of HIV reverse transcriptase and HIV replication in H9 lymphocyte cells. |
TN5011 |
Shizukaol B |
Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinf...
|
TN5012 |
Shizukaol C |
1. Shizukaol C shows anti-HIV-1 replication activities in both wild-type HIV-1 and two NNRTIs-resistant strains. <br/> 2. Shizukaol C has significant cytotoxici...
|
TN5133 |
3',5,5',7-Tetrahydroxy-4',6-dimethoxyflavone |
5,7,3',5'-tetrahydroxy-6,4'-dimethoxyflavone exhibits anti-HIV-1 activity in the anti-syncytium assay using (∆Tat/rev)MC99 virus and 1A2 cell line system, it ...
|
TN5177 |
Trigothysoid N |
Trigothysoid N may have anti-HIV activity. |
TN5191 |
Tsugafolin |
Tsugafolin has weak anti-HIV activity. |
TN5243 |
Vitexilactone |
Vitexilactone is a HIV-1 reverse transcriptase inhibitor in virtual screening against Indonesian Herbal Database using AutoDock4 performed on HIV-1 reverse tran...
|
TN5263 |
Xanthohumol |
Xanthohumol has anti-hepatitis C virus, anti-carcinogenic, free radical-scavenging, and anti-inflammatory activities, it can inhibit HIV-1 induced cytopathic ef...
|
TP1348 |
FC131 TFA |
FC131 TFA is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to CXCR4(IC50 : 4.5 nM ), and has anti-hiv activity. |
TP1809 |
TAT |
TAT (YGRKKRRQRRR) is derived from the transactivator of transcription (TAT) of human immunodeficiency virus-1 (HIV-1) and is a cell-penetrating peptide. TAT can...
|
TQ0217 |
Gomisin G |
Gomisin G is a natural compound and exhibits potent anti-HIV activity (EC50: 0.006 μg/mL; therapeutic index: 300). It is a good substrate of CYP2C9. |
TQ0297 |
Cenicriviroc |
Cenicriviroc is an orally active, dual antagonist of CCR2/CCR5. It also inhibits both HIV-1 and HIV-2, and displays potent anti-infective and anti-inflammatory ...
|