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Search Results for " hiv-protease "

108

Compounds

20

Natural Products

5

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T39729 HIV Protease Substrate 1
HIV Protease Substrate 1 is a fluorogenic compound that offers insights into the enzymatic activity of HIV protease, making it a valuable tool for studying this aspect.
T1883 Des(benzylpyridyl) Atazanavi HIV Protease
The N-dealkylated metabolite (M1) of Atazanavir, a HIV protease inhibitor.
T7779 Nelfinavir AG1341 HIV Protease
Nelfinavir (AG1341) is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV) (Ki=2 nM). Nelfinavir is a broad-spectrum, anticancer agent.
T7903 Saquinavir Ro 31-8959 SARS-CoV , HIV Protease
Saquinavir (Ro 31-8959) is a potent HIV protease inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS.
T76502 HIV-1, HIV-2 Protease Substrate
HIV-1, HIV-2 Protease Substrate is a compound serving as the substrate for the proteases of both HIV-1 and HIV-2, featuring four residues that allow for conservative substitutions at the substrate binding sites of these ...
T76485 HIV Protease Substrate I
HIV Protease Substrate I, a chromogenic substrate for HIV-1 protease, contains the protease's cleavage site [1].
T76511 HIV Protease Substrate IV
HIV Protease Substrate IV, a substrate for HIV (human immunodeficiency virus) protease, facilitates the measurement of HIV-1 protease activity [1].
T74939 HIV protease-IN-1
HIV protease-IN-1 (compound 1·succinate), a potent non-peptidic inhibitor of HIV protease, is utilized for AIDS research [1].
T1623 Lopinavir ABT-378 SARS-CoV , HIV Protease
Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation. Lopinavir is less affected by binding to serum proteins than the structurally-related dr...
T9854 HIV-1 inhibitor-6  3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo- HIV Protease
HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing inhibitor that blocks HIV replication.
T63949 HIV-1 protease-IN-2
HIV-1 protease-IN-2 is a potent inhibitor of HIV-1 protease (IC50: 2.53 nM). HIV-1 protease-IN-2 exhibits antiviral effects against DRV (Darunavir) sensitive or drug resistant HIV-1 mutants.
T76074 HIV Protease Substrate 1 TFA
HIV Protease Substrate 1 TFA, a fluorogenic substrate for HIV protease, facilitates the investigation of the enzyme's activity [1].
T79537 HIV-1 protease-IN-12 HIV Protease
HIV-1 protease-IN-12 (compound 35b) serves as a potent inhibitor of HIV-1 protease, exhibiting an IC50 value of 0.51 nM, and demonstrates efficacy against drug-resistant variant [1].
T74942 HIV-1 protease-IN-7 HIV Protease
HIV-1 protease-IN-7 (compound 16) is an orally active inhibitor of HIV-1 protease, exhibiting an IC50 of 3.52 nM and an EC50 of 37 nM [1].
T78950 HIV-1 protease-IN-8 HIV Protease
HIV-1 protease-IN-8 (compound 34b) is a potent inhibitor of the HIV-1 protease enzyme, exhibiting an IC50 of 0.32 nM. It demonstrates IC50 values of 0.29 μM for the wild-type HIV-1 (HIV-1 NL4-3) and 1.90 μM against a dru...
T2324 Darunavir TMC114 HIV Protease
Darunavir (TMC114) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administered in combination with other AN...
T64112 HIV-1 protease-IN-5
HIV-1 protease-IN-5 is an HIV-1 protease inhibitor (IC50: 1.64 nM). HIV-1 protease-IN-5 exhibits significant effects on wild-type and DRV-resistant HIV-1.
T63453 HIV-1 protease-IN-1
HIV-1 protease-IN-1 is a potent inhibitor of HIV-1 protease (IC50: 90 pM). HIV-1 protease-IN-1 has antiviral activity against B-HIV (EC50: 89 nM): HIV-1 protease-IN-1 was able to act on C-HIV strain ZM246 (EC50: 13.59 nM...
T63733 HIV-1 protease-IN-6
HIV-1 protease-IN-6 (compound 17d) is a potent inhibitor of HIV-1 protease (IC50: 21 pM, Ki: 4.7 pM). HIV-1 protease-IN-6 showed significant antiviral activity against DRV (darunavir) resistant mutants, even exceeding th...
T79536 HIV-1 protease-IN-11 HIV Protease
HIV-1 protease-IN-11 (compound 34a), an HIV-1 protease inhibitor, demonstrates potent inhibition with an IC50 of 0.41 nM and maintains substantial efficacy against drug-resistant variant [1].
T79493 HIV-1 protease-IN-10 PKC
HIV-1 protease-IN-10 (Compound 2), exhibiting HIV-1 latency reversing activity (IC50: 0.22 μM), selectively binds to the PKCδ C1b domain (IC50: 0.69 μM) and demonstrates stability against esterase-mediated hydrolysis [1]...
T6001 Nelfinavir Mesylate Viracept,Nelfin,AG1343,AG 1343 Mesylate HIV Protease
Nelfinavir Mesylate (Viracept) is an effective HIV protease inhibitor (Ki: 2 nM).
T79295 HIV-1 protease-IN-9 HIV Protease
HIV-1 protease-IN-9 (compound 5b), a potent HIV-1 protease inhibitor, exhibits strong antiviral efficacy with a dissociation constant (K_i) of 0.028 nM and a half-maximal inhibitory concentration (IC_50) of 66.8 nM [1].
T74488 HIV-1 protease-IN-4
HIV-1 protease-IN-4 (Compound II-22), a potent inhibitor of the HIV-1 protease, acts as a prodrug for atazanavir. It notably enhances the bioavailability of atazanavir in rat plasma, achieving a 5-fold increase in the ar...
T6388 Amprenavir 141W94,Prozei,KVX-478,VX-478 SARS-CoV , HIV Protease
Amprenavir (KVX-478) is a synthetic derivative of hydroxyethylamine sulfonamide that selectively binds to and inhibits human immunodeficiency virus (HIV) protease.
T1525 Ritonavir RTV,Abbott 84538,A 84538,ABT 538 Apoptosis , SARS-CoV , HIV Protease
Ritonavir (ABT 538) is a peptidomimetic agent that inhibits both HIV-1 and HIV-2 proteases. Ritonavir is highly inhibited by serum proteins but boosts the effect of other HIV proteases by blocking their degradation by cy...
T3335 Darunavir Ethanolate UIC 94017,Darunavir Ethanolate,TMC114 HIV Protease
Darunavir Ethanolate (UIC 94017) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administered in combination...
T3695 Pepstatin Pepstatin A,Pepsin Inhibitor S 735A,Ahpatinin C Amino Acids and Derivatives , Proteasome , HIV Protease , Autophagy
Pepstatin (Pepsin Inhibitor S 735A) is a specific aspartic proteases inhibitor produced by actinomycetes, and inhibits the aspartic proteases cathepsin D, pepsin and renin.
T0100L Atazanavir Zrivada,Reyataz,Latazanavir,BMS-232632 P450 , SARS-CoV , HIV Protease , P-gp
Atazanavir (BMS-232632)(BMS-232632) is an highly effective HIV-1 protease inhibitor.
T5863 Indinavir sulfate L735524 sulfate,MK-639 sulfate SARS-CoV , HIV Protease
Indinavir sulfate (L735524 sulfate) is a HIV protease inhibitor.It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM.
T0100 Atazanavir sulfate BMS-232632,BMS-232632 sulfate P450 , SARS-CoV , HIV Protease , P-gp
Atazanavir sulfate (BMS-232632 sulfate) is an azapeptide and HIV-PROTEASE INHIBITOR that is used in the treatment of HIV INFECTIONS and AIDS in combination with other ANTI-HIV AGENTS.
T0825 Ebselen SPI-1005,PZ-51,CCG-39161 Phosphatase , Virus Protease , Calcium Channel , COX , HIV Protease
Ebselen (CCG-39161) is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced b...
T8156 Saquinavir mesylate Ro 31-8959/003 HIV Protease , Autophagy
Saquinavir mesylate (Ro 31-8959/003) is an Inhibitor of HIV Proteaseused in antiretroviral therapy
T1776L Plerixafor octahydrochloride JM3100 octahydrochloride,Plerixafor 8HCl (AMD3100 8HCl),Plerixafor 8HCl,SID791 octahydrochloride,AMD 3100 octahydrochloride,JM 3100 8HCl Virus Protease , HIV Protease , CXCR
Plerixafor octahydrochloride (JM3100 octahydrochloride) blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting in hematopoietic stem cell (HSC) release from bone marrow a...
T4578 Tipranavir PNU-140690 SARS-CoV , HIV Protease
Tipranavir is a protease inhibitor that inhibits HIV-1 resistant to more than 1 protease inhibitor .Tipranavir effectively inhibits HIV-1 protease enzyme activity and dimerisation and has potent activity against multiple...
T77347 2-Amino-6-bromopyridine
2-Amino-6-bromopyridine has inhibitory effect on HIV-68 protease.
T8238 Fosamprenavir Calcium Salt Diallyl Trisulfide,GW433908G HIV Protease
Fosamprenavir Calcium Salt (GW433908G) (GW433908G) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility. Fosamprenavir Calcium Salt has Anti-HIV infection.
T24362 L 756423 L756423,MK-944a,MK944a,L-756,423,L-756423,MK 944a HIV Protease
L 756423 (L756423) is a novel potent and selective and competitive HIV protease inhibitor with a Ki value of 0.049 nM for HIV-1 PR.L 756423 blocks the spread of HIV(IIIb)-infected MT25 lymphocytes at 0.50-0.1 nM and can ...
T15683 L-689502 HIV Protease
L-689502 is a potent HIV-l protease inhibitor (IC50: 1 nM).
T39345 Lopinavir Metabolite M-1
Lopinavir Metabolite M-1, an active metabolite derived from Lopinavir, effectively inhibits the HIV protease enzyme with a Ki value of 0.7 pM. Additionally, in vitro studies have revealed notable antiviral properties ass...
T26552 Acetylpepstatin Ac-Val-Val-Sta-Ala-Sta-OH,Acetyl-pepstatin
Acetylpepstatin is an inhibitor of HIV-1 protease, HIV-2 protease, aspartyl protease.
T26446 A 77003 A-77003,Abbott 77003,A77003
A 77003 is a HIV-1 protease inhibitor. A77003 impairs HIV-1 protease-mediated Gag processing.
T24331 L 682679 L-682679,L-682,679,L682,679,L 682,679,L682679
L 682679 is an inhibitor of HIV protease.
T24343 L 694746 L 694,746,L694746,L-694,746,L694,746,L-694746
L 694746 is an inhibitor of HIV-1 protease.
T21039 PL 100 MK-8122,PL-100,PPL-100,PPL 100,MX-100
PL 100 could inhibit HIV-1 protease.
T24536 NIT
NIT is an HIV-1 protease inhibitor.
T24199 JG 365 JG-365,JG365
JG 365 is an HIV protease inhibitor.
T26024 R 87366 R87366,R-87366
R 87366 is used as a water-soluble HIV protease inhibitor.
T24336 L 687908 L687908,L-687,908,L 687,908,L-687908,L687,908
L 687908 is a potent inhibitor of hydroxyethylene-containing HIV protease.
T16555 PNU-103017 HIV Protease
PNU-103017 is an inhibitor of HIV protease.

Compounds

HIV Protease Substrate 1
T39729
Synonym:
Target:
Des(benzylpyridyl) Atazanavi
T1883
Synonym:
Target: HIV Protease
Nelfinavir
T7779
Synonym: AG1341
Target: HIV Protease
Saquinavir
T7903
Synonym: Ro 31-8959
Target: SARS-CoV, HIV Protease
HIV-1, HIV-2 Protease Substrate
T76502
Synonym:
Target:
HIV Protease Substrate I
T76485
Synonym:
Target:
HIV Protease Substrate IV
T76511
Synonym:
Target:
HIV protease-IN-1
T74939
Synonym:
Target:
Lopinavir
T1623
Synonym: ABT-378
Target: SARS-CoV, HIV Protease
HIV-1 inhibitor-6 
T9854
Synonym: 3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-
Target: HIV Protease
HIV-1 protease-IN-2
T63949
Synonym:
Target:
HIV Protease Substrate 1 TFA
T76074
Synonym:
Target:
HIV-1 protease-IN-12
T79537
Synonym:
Target: HIV Protease
HIV-1 protease-IN-7
T74942
Synonym:
Target: HIV Protease
HIV-1 protease-IN-8
T78950
Synonym:
Target: HIV Protease
Darunavir
T2324
Synonym: TMC114
Target: HIV Protease
HIV-1 protease-IN-5
T64112
Synonym:
Target:
HIV-1 protease-IN-1
T63453
Synonym:
Target:
HIV-1 protease-IN-6
T63733
Synonym:
Target:
HIV-1 protease-IN-11
T79536
Synonym:
Target: HIV Protease
HIV-1 protease-IN-10
T79493
Synonym:
Target: PKC
Nelfinavir Mesylate
T6001
Synonym: Viracept,Nelfin,AG1343,AG 1343 Mesylate
Target: HIV Protease
HIV-1 protease-IN-9
T79295
Synonym:
Target: HIV Protease
HIV-1 protease-IN-4
T74488
Synonym:
Target:
Amprenavir
T6388
Synonym: 141W94,Prozei,KVX-478,VX-478
Target: SARS-CoV, HIV Protease
Ritonavir
T1525
Synonym: RTV,Abbott 84538,A 84538,ABT 538
Target: Apoptosis, SARS-CoV, HIV Protease
Darunavir Ethanolate
T3335
Synonym: UIC 94017,Darunavir Ethanolate,TMC114
Target: HIV Protease
Pepstatin
T3695
Synonym: Pepstatin A,Pepsin Inhibitor S 735A,Ahpatinin C
Target: Amino Acids and Derivatives, Proteasome, HIV Protease, Autophagy
Atazanavir
T0100L
Synonym: Zrivada,Reyataz,Latazanavir,BMS-232632
Target: P450, SARS-CoV, HIV Protease, P-gp
Indinavir sulfate
T5863
Synonym: L735524 sulfate,MK-639 sulfate
Target: SARS-CoV, HIV Protease
Atazanavir sulfate
T0100
Synonym: BMS-232632,BMS-232632 sulfate
Target: P450, SARS-CoV, HIV Protease, P-gp
Ebselen
T0825
Synonym: SPI-1005,PZ-51,CCG-39161
Target: Phosphatase, Virus Protease, Calcium Channel, COX, HIV Protease
Saquinavir mesylate
T8156
Synonym: Ro 31-8959/003
Target: HIV Protease, Autophagy
Plerixafor octahydrochloride
T1776L
Synonym: JM3100 octahydrochloride,Plerixafor 8HCl (AMD3100 8HCl),Plerixafor 8HCl,SID791 octahydrochloride,AMD 3100 octahydrochloride,JM 3100 8HCl
Target: Virus Protease, HIV Protease, CXCR
Tipranavir
T4578
Synonym: PNU-140690
Target: SARS-CoV, HIV Protease
2-Amino-6-bromopyridine
T77347
Synonym:
Target:
Fosamprenavir Calcium Salt
T8238
Synonym: Diallyl Trisulfide,GW433908G
Target: HIV Protease
L 756423
T24362
Synonym: L756423,MK-944a,MK944a,L-756,423,L-756423,MK 944a
Target: HIV Protease
L-689502
T15683
Synonym:
Target: HIV Protease
Lopinavir Metabolite M-1
T39345
Synonym:
Target:
Acetylpepstatin
T26552
Synonym: Ac-Val-Val-Sta-Ala-Sta-OH,Acetyl-pepstatin
Target:
A 77003
T26446
Synonym: A-77003,Abbott 77003,A77003
Target:
L 682679
T24331
Synonym: L-682679,L-682,679,L682,679,L 682,679,L682679
Target:
L 694746
T24343
Synonym: L 694,746,L694746,L-694,746,L694,746,L-694746
Target:
PL 100
T21039
Synonym: MK-8122,PL-100,PPL-100,PPL 100,MX-100
Target:
NIT
T24536
Synonym:
Target:
JG 365
T24199
Synonym: JG-365,JG365
Target:
R 87366
T26024
Synonym: R87366,R-87366
Target:
L 687908
T24336
Synonym: L687908,L-687,908,L 687,908,L-687908,L687,908
Target:
PNU-103017
T16555
Synonym:
Target: HIV Protease
1 2 3
Cat No. Product Name Synonyms Targets
T5783 Rosamultin Antioxidant , HIV Protease
Rosamultin has antioxidant, antiinflammatory/antinociceptive properties,and has anti-human immunodeficiency virus (HIV) activity.
TN1059 Ganoderic acid B IL Receptor , HIV Protease , JAK , STAT
Ganoderic acid B is a chemical marker in quality control of G. lucidum and related products. Ganoderic acid B-containing herbs has potential influence towards therapeutic window of trifluoperazine.Ganoderic acid B has an...
T4S1383 Escin IA Aescin IA,Escin IA;Aescin IA,Escin IA HIV Protease
Escin IA (Escin IA;Aescin IA) is a triterpene saponin isolated from horse chestnut, which inhibits HIV-1 protease with IC50 values of 35 μM. Escin IA has anti-TNBC metastasis activity, and its action mechanisms involved ...
T4S1387 Isoescin IA HIV Protease
Isoescin IA is a triterpenoid saponin isolated from the seeds of Aesculus chinensis. It has anti-HIV-1 protease activity.
T5429 Theaflavin 3,3'-digallate 8-Gingerol,TFDG Virus Protease , Antioxidant , HIV Protease , HSV
Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregul...
T2S0223 Isosinensetin 6-Demethoxynobiletin Antioxidant , HIV Protease , Antibacterial , P-gp
1. Isosinensetin (6-Demethoxynobiletin) shows antioxidant and HIV-1 protease inhibiting activities.
T3323 Ursonic Acid CCRIS 7123,NSC4060,Prunol,3-Ketoursolic acid,Malol,TOS-BB-0966 Apoptosis , HIV Protease , Endogenous Metabolite
Ursonic Acid (TOS-BB-0966) belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton. It has potential as HIV-1 Protease Inhibitor.
TQ0217 Gomisin G P450 , HIV Protease
Gomisin G is a natural compound and exhibits potent anti-HIV activity (EC50: 0.006 μg/mL; therapeutic index: 300). It is a good substrate of CYP2C9.
TN5675 Ganomycin I
Ganomycin I inhibits the activity of HIV-1 protease.
T5S0983 Absinthin Absinthiin,Absynthin HIV Protease
Absinthin (Absynthin) is a weak HIV-1 protease inhibitor.
TN4705 Oleoside Others , HIV Protease
Oleoside can be extracted from Olea europaea and Zizyphus lotus L. twigs and may be used to inhibit HIV-1 protease.
TN4347 Jacoumaric acid HIV Protease
Jacoumaric acid is a lead molecule from the library or database of natural compounds as a HIV-1 protease inhibitor.
T75705 Pepstatin Trifluoroacetate
Pepstatin Trifluoroacetate (Pepstatin A), a specific and orally active aspartic protease inhibitor produced by actinomycetes, demonstrates inhibition efficacy with IC50 values of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM, a...
T75562 Ganoderic acid GS-1
Ganoderic acid GS-1, an extensively oxygenated lanostane-type triterpenoid, exhibits anti-HIV-1 protease activities, displaying an IC50 value of 58 μM [1].
T10928 Cytochalasin A HIV Protease
Cytochalasin A is a cell-permeable fungal toxin and is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC50 = 3 μM), inhibits actin polymerization and interferes with microtubu...
TN4109 Ganolucidic acid A HIV Protease
Ganolucidic acid A exhibits cytotoxicity, has inhibitory activities against human HeLa cervical cancer cell lines. It shows significant anti-human immunodeficiency virus (anti-HIV)-1 protease activity with IC50 values of...
T79953 Acetyl-binankadsurin A HIV Protease
Acetyl-binankadsurin A (compound 5), a lignan obtained from Kadsura longipedunculata, exhibits weak inhibitory effects on HIV-1 protease, demonstrating an IC50 value exceeding 100 μg/mL [1].
TMA1012 Ganoderiol F Androgen Receptor , HIV Protease , Autophagy
Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency virus-1 protease with IC(50) values of 20-40 microM. It induced...
TN1660 Ganoderic acid C1 IL Receptor , TNF , NF-κB , MAPK , COX , HIV Protease , DNA/RNA Synthesis
Ganoderic acid C1 has anti-inflammatory activity, has potential for treating TNF-α± mediated inflammation in asthma and other inflammatory diseases. Ganoderic acid C1 has anti-tumor-promoting activity. It is moderately a...
TN1670 Ganodermanondiol HIV Protease , Nrf2 , AMPK
Ganodermanondiol exhibits potent cytoprotective effects on t-BHP-induced hepatotoxicity in human liver-derived HepG2 cells, presumably through Nrf2-mediated antioxidant enzymes and AMPK.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00767 Cystatin C Protein, Human, Recombinant (His) Human HEK293
Cystatin C, also known as Cystatin-3 (CST3) is a secreted type 2 cysteine protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal functio...
TMPY-01711 Serpin B2 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, infl...
TMPY-00640 Cystatin C Protein, Human, Recombinant Human HEK293
Cystatin C, also known as Cystatin-3 (CST3) is a secreted type 2 cysteine protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal functio...
TMPY-01370 Cystatin C Protein, Mouse, Recombinant (His) Mouse HEK293
Cystatin C, also known as Cystatin-3 (CST3) is a secreted type 2 cysteine protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal functio...
TMPY-02056 Cystatin C Protein, Rat, Recombinant (His) Rat HEK293
Cystatin C, also known as Cystatin-3 (CST3) is a secreted type 2 cysteine protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal functio...
Cat No. Product Name
L1100 Protease Inhibitor Library

344 compounds
A unique collection of 344 protease and proteasome inhibitors for research in chemical genomics, and drug screening;
TargetMol