Home Tools
Log in
Cart

HIV Protease

HIV-1 protease (PR) is a retroviral aspartyl protease (retropepsin), an enzyme involved with peptide bond hydrolysis in retroviruses, that is essential for the life-cycle of HIV, the retrovirus that causes AIDS. HIV protease cleaves newly synthesized polyproteins (namely, Gag and Gag-Pol[3]) at nine cleavage sites to create the mature protein components of an HIV virion, the infectious form of a virus outside of the host cell. Without effective HIV protease, HIV virions remain uninfectious.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T16112 ML67-33 1443290-89-8 98%
ML67-33
ML67-33 rapidly and reversibly affects K2P2.1 (TREK-1) (EC50s: 36.3 μM and 9.7 μM in cell-free and HEK293 cells, respectively). ML67-33 is a selective activator ...
TN1670 Ganodermanondiol 107900-76-5 98%
Ganodermanondiol
Ganodermanondiol exhibits potent cytoprotective effects on t-BHP-induced hepatotoxicity in human liver-derived HepG2 cells, presumably through Nrf2-mediated anti...
T12420 Pentosan Polysulfate 37300-21-3 98%
Pentosan Polysulfate
Pentosan Polysulfate is a potent and selective anti-HIV agent.with anti-inflammatory and pro-chondrogenic properties,and used for treatment of interstitial cysti...
TN4911 Rhuscholide A 944804-58-4 98%
Rhuscholide A
Rhuscholide A possesses significant anti-HIV-1 activity with an EC50 value of 1.62 microM and a therapeutic index (TI) of 42.40.
TN5012 Shizukaol C 142279-41-2 98%
Shizukaol C
1. Shizukaol C shows anti-HIV-1 replication activities in both wild-type HIV-1 and two NNRTIs-resistant strains.
2. Shizukaol C has significant cytotoxicit...
T16555 PNU-103017 166335-18-8 98%
PNU-103017
PNU-103017 is an inhibitor of HIV protease.
TN1302 6,8-Diprenylorobol 66777-70-6 98%
6,8-Diprenylorobol
6,8-Diprenylorobol possesses weaker anti-H. pylori activity, it may be a useful chemopreventive agent for peptic ulcer or gastric cancer in H. pylori-infected in...
TN4264 Isoapetalic acid 34366-34-2 98%
Isoapetalic acid
Isoapetalic acid and apetalic acid exhibit cytotoxic activities towards both cancer cell lines(human breast cancer (MCF-7) and human lung carcinoma (A-549) cell ...
T39264L Cyclotriazadisulfonamide hydrochloride 392287-03-5 98%
Cyclotriazadisulfonamide hydrochloride
Cyclotriazadisulfonamide hydrochloride is a selective inhibitor of CD4-targeted HIV entry and inhibits the co-translational translocation of human CD4 into the E...
TN1852 Lancifodilactone F 850878-47-6 98%
Lancifodilactone F
Lancifodilactone F exerts minimal cytotoxicity against C8166 cells (CC50 > 200 microg/mL) and shows anti-HIV activity with EC50 = 20.69 +/- 3.31 microg/mL and a ...
TN4835 Przewalskin 119400-87-2 98%
Przewalskin
Przewalskin A and Przewalskin B showed modest anti-HIV-1 activity with EC50 = 41 and 30 microg/mL, respectively.
T10714 CCR5 antagonist 1 716354-86-8 98%
CCR5 antagonist 1
CCR5 antagonist 1 is a CCR5 antagonist extracted from WO 2004054974 A2. It can inhibit HIV replication.
T30791 Censavudine 634907-30-5 98%
Censavudine
Censavudine (OBP-601) is a nucleoside analog, a nucleoside reverse transcriptase inhibitor, used for the prevention and treatment of human immunodeficiency virus...
TMA1012 Ganoderiol F 114567-47-4 98%
Ganoderiol F
Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency viru...
T12420L Pentosan Polysulfate Sodium (W/W 43%) 140207-93-8 98%
Pentosan Polysulfate Sodium (W/W 43%)
Pentosan Polysulfate Sodium is a potent and selective anti-HIV agent.with anti-inflammatory and pro-chondrogenic properties,and used for treatment of interstitia...
TN4934 Salaspermic acid 71247-78-4 98%
Salaspermic acid
Salaspermic acid is an inhibitor of HIV reverse transcriptase and HIV replication in H9 lymphocyte cells.
T13796 Nigranoic acid 39111-07-4 98%
Nigranoic acid
Nigranoic acid is a natural product,and inhibits HIV-1 reverse transcriptase.
TQ0073 Andropanolide 869807-57-8 98%
Andropanolide
Andropanolide is a dipterocarbon from Andrographis paniculata with anti-HIV, antimalarial and anticancer activities and inhibits Lipopolysaccharides (LPS)-stimul...
TN3444 Aristolactam BII 53948-09-7 98%
Aristolactam BII
Aristolactam BII exhibits antimicrobial and antiinflammatory activity, it shows significant activity towards DPPH radical scavenging and potent inhibitory effect...
T11189 Emtricitabine S-oxide 152128-77-3 98%
Emtricitabine S-oxide
Emtricitabine, a potent nucleoside reverse transcriptase inhibitor, is employed for managing HIV infection. Emtricitabine S-oxide, also known as Emtricitabine su...
ML67-33
T16112
ML67-33 rapidly and reversibly affects K2P2.1 (TREK-1) (EC50s: 36.3 μM and 9.7 μM in cell-free and HEK293 cells, respectively). ML67-33 is a selective activator ...
Ganodermanondiol
TN1670
Ganodermanondiol exhibits potent cytoprotective effects on t-BHP-induced hepatotoxicity in human liver-derived HepG2 cells, presumably through Nrf2-mediated anti...
Pentosan Polysulfate
T12420
Pentosan Polysulfate is a potent and selective anti-HIV agent.with anti-inflammatory and pro-chondrogenic properties,and used for treatment of interstitial cysti...
Rhuscholide A
TN4911
Rhuscholide A possesses significant anti-HIV-1 activity with an EC50 value of 1.62 microM and a therapeutic index (TI) of 42.40.
Shizukaol C
TN5012
1. Shizukaol C shows anti-HIV-1 replication activities in both wild-type HIV-1 and two NNRTIs-resistant strains. <br/> 2. Shizukaol C has significant cytotoxicit...
PNU-103017
T16555
PNU-103017 is an inhibitor of HIV protease.
6,8-Diprenylorobol
TN1302
6,8-Diprenylorobol possesses weaker anti-H. pylori activity, it may be a useful chemopreventive agent for peptic ulcer or gastric cancer in H. pylori-infected in...
Isoapetalic acid
TN4264
Isoapetalic acid and apetalic acid exhibit cytotoxic activities towards both cancer cell lines(human breast cancer (MCF-7) and human lung carcinoma (A-549) cell ...
Cyclotriazadisulfonamide hydrochloride
T39264L
Cyclotriazadisulfonamide hydrochloride is a selective inhibitor of CD4-targeted HIV entry and inhibits the co-translational translocation of human CD4 into the E...
Lancifodilactone F
TN1852
Lancifodilactone F exerts minimal cytotoxicity against C8166 cells (CC50 > 200 microg/mL) and shows anti-HIV activity with EC50 = 20.69 +/- 3.31 microg/mL and a ...
Przewalskin
TN4835
Przewalskin A and Przewalskin B showed modest anti-HIV-1 activity with EC50 = 41 and 30 microg/mL, respectively.
CCR5 antagonist 1
T10714
CCR5 antagonist 1 is a CCR5 antagonist extracted from WO 2004054974 A2. It can inhibit HIV replication.
Censavudine
T30791
Censavudine (OBP-601) is a nucleoside analog, a nucleoside reverse transcriptase inhibitor, used for the prevention and treatment of human immunodeficiency virus...
Ganoderiol F
TMA1012
Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency viru...
Pentosan Polysulfate Sodium (W/W 43%)
T12420L
Pentosan Polysulfate Sodium is a potent and selective anti-HIV agent.with anti-inflammatory and pro-chondrogenic properties,and used for treatment of interstitia...
Salaspermic acid
TN4934
Salaspermic acid is an inhibitor of HIV reverse transcriptase and HIV replication in H9 lymphocyte cells.
Nigranoic acid
T13796
Nigranoic acid is a natural product,and inhibits HIV-1 reverse transcriptase.
Andropanolide
TQ0073
Andropanolide is a dipterocarbon from Andrographis paniculata with anti-HIV, antimalarial and anticancer activities and inhibits Lipopolysaccharides (LPS)-stimul...
Aristolactam BII
TN3444
Aristolactam BII exhibits antimicrobial and antiinflammatory activity, it shows significant activity towards DPPH radical scavenging and potent inhibitory effect...
Emtricitabine S-oxide
T11189
Emtricitabine, a potent nucleoside reverse transcriptase inhibitor, is employed for managing HIV infection. Emtricitabine S-oxide, also known as Emtricitabine su...
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
TargetMol