haspin kinase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TQ0111	LDN-192960		DYRK , Haspin Kinase
	LDN-192960 is a potent inhibitor of Haspin and DYRK2 (IC50s: 10 nM and 48 nM).		DYRK , Haspin Kinase
T9521	CHR-6494 TFA		Others
	CHR-6494 TFA is a potent haspin inhibitor, with an IC50 of 2 nM. It inhibits histone H3T3 phosphorylation. CHR-6494 TFA induces the apoptosis of cancer cells, including melanoma and breast cancer. CHR-6494 TFA can be use...		Others
T6745	5-Iodotubercidin	5-ITu,NSC 113939	Adenosine Receptor
	5-Iodotubercidin (NSC-113939) is a potent adenosine kinase inhibitor with IC50 of 26 nM. It inhibits nucleoside transporter, CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2 and PKC.		Adenosine Receptor
T62011	LDN-209929 dihydrochloride
	LDN-209929 dihydrochloride is a potent and selective inhibitor of haspin kinase (IC50= 55 nM). LDN-209929 dihydrochloride shows180-fold selectivity verses DYRK2 (IC50= 9.9 μM).
T24396	LDN-209929	LDN-209929 dihydrochloride,LDN209929 dihydrochloride,LDN 209929 dihydrochloride
	LDN-209929 2HCl is a potent and selective inhibitor of haspin kinase.
T11830	LDN-192960 hydrochloride		Others
	LDN-192960 hydrochloride is an inhibitor of Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) and Haspin with IC50s of 48 nM and 10 nM, respectively.		Others
T60477	Haspin-IN-1
	Haspin-IN-1 (compound 2a) is an inhibitor of haspin (haploid germ cell-specific nuclear protein kinase) with an IC50 of 119 nM. Haspin-IN-1 also inhibits CLK1, DYRK1A, and CDK9 with IC50 of 221 nM, 916.3 nM, and 406.8 nM...
T62417	MELK-8a
	MELK-8a (NVS-MELK8a) is a potent and selective inhibitor of maternal embryonic leucine elongation kinase (MELK) (IC50: 2 nM). 0.42 μM). Among them, MELK plays an important role in regulating mitosis in cancer cells.

Compounds

LDN-192960

TQ0111

Synonym:

Target: DYRK, Haspin Kinase

Synonym: 5-ITu,NSC 113939

Target: Adenosine Receptor

LDN-209929 dihydrochloride

Synonym: LDN-209929 dihydrochloride,LDN209929 dihydrochloride,LDN 209929 dihydrochloride

Target:

LDN-192960 hydrochloride

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04774	ALK-2/ACVR1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-01096	ALK-2/ACVR1 Protein, Mouse, Recombinant (His & hFc)	Mouse	HEK293
	ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-03707	ALK-2/ACVR1 Protein, Canine, Recombinant (His)	Canine	HEK293
	ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-03247	ALK-2/ACVR1 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293
	ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-00658	ALK-2/ACVR1 Protein, Human, Recombinant (His & hFc)	Human	HEK293
	ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-03157	ALK-2/ACVR1 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-03706	ALK-2/ACVR1 Protein, Canine, Recombinant (hFc)	Canine	HEK293
	ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...