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Cat No. | Product Name | Synonyms | Targets |
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T8851 | I3MT-3 | HMPSNE | Hippo pathway |
I3MT-3 (HMPSNE) (HMPSNE) is a potent, selective and cell membrane permeability inhibitor of 3-mercaptopyruvate sulfur transferase (3MST), which targets the persulfated cysteine residues located at the active site of 3MST... | |||
T61728 | MY-875 | ||
MY-875 is a potent microtubulin polymerization inhibitor that competes at colchicine binding sites, exhibiting an IC50 value of 0.92 μM. It effectively suppresses microtubulin polymerization, exerting its inhibitory effe... | |||
T73429 | VT02956 | ||
VT02956 is a LATS inhibitor ( IC 50 : 0.76 nM for LATS1, 0.52 nM for LATS2). VT02956 targets the Hippo pathway. VT02956 inhibits ESR1 expression and growth of ER+ breast cancer cell lines and patient-derived tumor organo... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04398 | MST1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Dysregulation of MST1/STK4, a key kinase component of the Hippo-YAP pathway, is linked to the etiology of many cancers with poor prognosis. STK4/Hippo pathway may have important therapeutic implications for cancer. The t... | |||
TMPH-01662 | Merlin Protein, Human, Recombinant (His) | Human | E. coli |
Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergisti... | |||
TMPJ-01335 | MOB1A Protein, Human, Recombinant (His) | Human | E. coli |
MOB Kinase Activator 1A (MOB1A) belongs to the MOB1/phocein family, which acts as an activator of LATS1/2 in the Hippo signaling pathway, plays a key role in organ size control and tumor suppression by restricting prolif... | |||
TMPH-02223 | TEAD4 Protein, Human, Recombinant (His) | Human | E. coli |
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is... | |||
TMPH-02226 | TEAD3 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is... | |||
TMPH-02224 | TEAD4 Protein, Human, Recombinant (His & Myc) | Human | Baculovirus |
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is... | |||
TMPH-02943 | TEAD4 Protein, Mouse, Recombinant | Mouse | E. coli |
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is... | |||
TMPH-02225 | TEAD2 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is... | |||
TMPY-03416 | TNFAIP8 Protein, Human, Recombinant (His) | Human | E. coli |
Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8) family is a newly identified protein with vital roles in maintaining immune homeostasis. Tumor necrosis factor-alpha-inducible protein 8 (TNFAIP8) is a TNF-al... | |||
TMPH-02942 | TEAD4 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is... | |||
TMPH-02222 | TEAD1 Protein, Human, Recombinant (His) | Human | E. coli |
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is... | |||
TMPH-01018 | BMP-6 Protein, Human, Recombinant (His) | Human | E. coli |
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes including cartilage and bone formation. Plays also an important role in the regulation of iron metabolism by acting as ... | |||
TMPH-03764 | YAP1 Protein, Human, Recombinant (His) | Human | Yeast |
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor su... |