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Cat No. | Product Name | Synonyms | Targets |
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T38634 | Histamine H4 receptor antagonist-1 | Histamine H4 receptor antagonist-1 | |
Histamine H4 receptor antagonist-1 is a potent antagonist of the histamine H4 receptor. | |||
T10680 | Carebastine | Histamine Receptor | |
Carebastine, the active metabolite of Ebastine, is an antagonist of the histamine H1 receptor. | |||
T22842 | HTMT dimaleate | Histamine Trifluoromethyl Toluidide Dimaleate | Histamine Receptor |
HTMT dimaleate (Histamine Trifluoromethyl Toluidide Dimaleate) is an H1 and H2 receptor agonist. | |||
T22724 | Dimaprit dihydrochloride | NOS , NO Synthase , Histamine Receptor | |
Dimaprit dihydrochloride is a selective histamine H2 receptor agonist. Dimaprit dihydrochloride also inhibits nNOS with an IC50 of 49 μM. It can stimulate gastric acid secretion. | |||
T9717 | Chlorcyclizine | HCV Protease , Histamine Receptor | |
CHLORCYCLIZINE is a histamine H1 antagonist and a potent hepatitis C virus (HCV) entry inhibitor. | |||
T9353 | OXOMEMAZINE | AChR , Histamine Receptor | |
Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic activity. Oxomemazine is a selective antagonist of mycotoxins M1 receptors, showing high (Ki=84 nM, M1 receptors) and low ... | |||
T8439 | Clobenpropit dihydrobromide | Apoptosis , Histamine Receptor | |
Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07) | |||
T7477 | Antazoline | Others | |
Antazoline has antihistamine and anticholinergic effects.It used to treat a variety of arrhythmias. | |||
T5829 | H4 Receptor antagonist 1 | Histamine Receptor | |
H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC50 of 19 nM. | |||
T4563 | Thonzylamine | neohetramine | Histamine Receptor |
Thonzylamine (neohetramine) is an antihistamine and anticholinergic drug. It is available as combination products with Clofedanol or Phenylephrine for temporary relief of symptoms of common cold, hay fever (allergic rhin... | |||
T7085 | Mebhydrolin | Mebhydroline | Histamine Receptor |
Mebhydrolin (Mebhydroline) is a specific histamine H1 receptor antagonist. | |||
T4250 | Bilastine | Bilaxten | Histamine Receptor |
Bilastine (Bilaxten) is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action. | |||
T19680 | Zotepine | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Histamine Receptor | |
Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM, 3.3 nM, 7.3 nM, and 8 nM, respectively. Zotepine is a second... | |||
T11723L | JNJ-39758979 | Histamine Receptor | |
JNJ-39758979 is a selective and high-affinity histamine H4 receptor antagonist (Kis: 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H4 receptor, respectively). JNJ-39758979 functionally antagonizes histamine... | |||
T36949 | Niaprazine | 5-HT Receptor , Adrenergic Receptor , Histamine Receptor | |
Niaprazine is a histamine H1-receptor antagonist with marked sedative properties. Niaprazine has antihistamine and antiserotonin activities and can be used for sleep disorder research[1][2]. Niaprazine exhibits a low aff... | |||
T7564 | Chlorphenoxamine | Contristamine | Histamine Receptor |
Chlorphenoxamine (Contristamine) is an antihistamine and anticholinergic used as an antipruritic and antiparkinsonian agent. | |||
T1278 | Astemizole | Laridal,Histaminos,Paralergin | Potassium Channel , Histamine Receptor |
Astemizole (Laridal) is a synthetic piperidinyl-benzimidazol derivative with antiallergic properties, acts as a reversible competitive inhibitor of histamine H1 receptors, with less anticholinergic effects compared to re... | |||
T12489 | Pimethixene | Calmixen,Pimetixene | Dopamine Receptor , 5-HT Receptor , AChR , Histamine Receptor |
Pimethixene (Calmixen) is a highly potent 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors antagonist(pKis of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 ... | |||
T0081 | Lafutidine | FRG-8813 | 5-HT Receptor , Histamine Receptor |
Lafutidine (FRG-8813) is a newly developed histamine H(2)-receptor antagonist, which can inhibit gastric acid secretion. | |||
T3963 | VUF10460 | Histamine Receptor | |
VUF10460 is a non-imidazole histamine H4 receptor agonist. | |||
T4566 | Lodoxamide | Lodoxamidum | GPR , Histamine Receptor |
Lodoxamide (Lodoxamidum) is an antiallergic drug acting as a mast-cell stabilizer. It is effective in the treatment of asthma and allergic conjunctivitis. | |||
T4196 | Betahistine EP Impurity C | NSC19005 | Others , Histamine Receptor |
Betahistine EP Impurity C (NSC19005) is structurally related to Betahistine. Betahistine EP Impurity C is a dimer of Betahistine. | |||
T0074 | Chlorprothixene | Truxal,Clorprotixeno,Taractan | Dopamine Receptor , 5-HT Receptor , Antibacterial , Histamine Receptor |
Chlorprothixene (Truxal) is a typical antipsychotic drug of the thioxanthene class, which was the first of the series to be synthesized. | |||
T8514 | LML134 | LML-134 | Histamine Receptor |
LML134 (LML-134) is an inverse agonist of Histamine 3 receptor (H3R)(hH3R cAMP and hH3R bdg with Kis of 0.3 nM and 12 nM). | |||
T22713 | Decloxizine | Histamine Receptor | |
Decloxizine is a H1 receptor antagonist | |||
T16280 | Nedocromil | FPL 59002 | Leukotriene Receptor , Prostaglandin Receptor , Histamine Receptor |
Nedocromil (FPL 59002) inhibits the action or formation of multiple mediators. Which including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2). | |||
T25180 | Bromodiphenhydramine hydrochloride | Others | |
Bromodiphenhydramine hydrochloride is a new antihistaminic in the control of cutaneous. | |||
TQ0066 | GSK189254A | GSK189254 | Histamine Receptor |
GSK189254A (GSK189254) is a potent and specific histamine H3 receptor antagonist (pKi values: 9.59-9.90 and 8.51-9.17 for human and rat H3). | |||
T7413 | JNJ-5207852 | Histamine Receptor | |
JNJ-5207852 is a novel, non-imidazole histamine H3 receptor antagonist, with high affinity at the rat (pKi=8.9) and human (pKi=9.24) H3 receptor. | |||
T16759 | Ritanserin | R 55667 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Histamine Receptor |
Ritanserin (R 55667) is a highly effective, relatively selective, long-acting antagonist of 5-HT2 receptor (IC50: 0.9 nM), less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors. | |||
T4099 | S 38093 | S38093,S-38093 | Histamine Receptor |
S 38093 is a brain-penetrant antagonist of the H3 receptor (Ki: 8.8/1.44/1.2 μM, for rat/mouse/human). | |||
T1822 | Clemizole | HCV Protease , Histamine Receptor | |
Clemizole is an H1 histamine receptor antagonist, can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication. | |||
T1469 | Levocetirizine | Levocetirizine HCl | Histamine Receptor |
Levocetirizine is a Histamine-1 Receptor Antagonist. The mechanism of action of levocetirizine is as a Histamine H1 Receptor Antagonist. | |||
T4551 | Acrivastine | Acrivastin,BW825C,Semprex | Histamine Receptor |
Acrivastine (Acrivastin) is a short-acting histamine 1 receptor antagonist. | |||
T1336 | Benztropine mesylate | Benzotropine mesylate,Benzatropine mesylate,Benztropine methanesulfonate | Dopamine Receptor , AChR , Histamine Receptor |
Benztropine mesylate (Benztropine methanesulfonate) is a centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON DISEASE. Benztropine also inhibits the uptake of dopamine. | |||
T22746 | Tesmilifene fumarate | DPPE fumarate | Histamine Receptor |
Tesmilifene fumarate (DPPE fumarate) (DPPE fumarate) is an H1C receptor antagonist。 | |||
T15195 | Ebrotidine | FI3542 | Histamine Receptor |
Ebrotidine (FI3542) is a competitive H2-receptor antagonist with Ki of 127.5 nM. Ebrotidine has a potent antisecretory activity and evidenced gastroprotection. | |||
T7524 | Metiamide | SK&F 92058 | Histamine Receptor |
Metiamide (SK&F 92058) is a histamine H2-receptor antagonist . | |||
T1627 | Famotidine | MK-208 | Histamine Receptor |
Famotidine (MK-208) is a propanimidamide and histamine H2-receptor antagonist with antacid activity. As a competitive inhibitor of histamine H2-receptors located on the basolateral membrane of the parietal cell, famotidi... | |||
T6562 | Latrepirdine dihydrochloride | Dimebolin dihydrochloride,Latrepirdine,Latrepirdine 2HCl,Dimebolin | Beta Amyloid , 5-HT Receptor , Adrenergic Receptor , GluR , Autophagy , Histamine Receptor |
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets, including histamine receptors, GluR, and 5-HT receptors, used as an antihistamine drug. | |||
T2004 | Ciproxifan maleate | FUB 359 maleate,FUB 359 | Histamine Receptor |
Ciproxifan maleate (FUB 359)(FUB-359 maleate) is a highly potent and selective histamin H3-receptor antagonist with IC50 of 9.2 nM, with low apparent affinity at other receptor subtypes. | |||
T0137 | Mirtazapine | 6-Azamianserin,Org3770 | Dopamine Receptor , 5-HT Receptor , Opioid Receptor , Adrenergic Receptor , Histamine Receptor |
Mirtazapine (6-Azamianserin) is a tetracyclic antidepressant with a somewhat unique mechanism of action. Mirtazapine therapy can be associated with transient asymptomatic elevations in serum aminotransferase levels and h... | |||
T6164 | Ciproxifan | FUB-359 | Histamine Receptor |
Ciproxifan (FUB-359) is a highly effective and specific histamin H3-receptor antagonist (IC50: 9.2 nM). | |||
T1090 | Perphenazine | Perphenazin,Etaperazine,Trilafon | CaMK , Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Histamine Receptor |
Perphenazine (Trilafon) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties. | |||
T0445L | Promethazine hydrochloride | Promethazine HCl,Phenergan | Adrenergic Receptor , Histamine Receptor |
Promethazine hydrochloride (Promethazine HCl) , the first-generation antihistamine, is a strong antagonist of the H1 receptor and a moderate antagonist of the mACh receptor, moderate affinity for 5-HT2A, 5-HT2C, D2 and α... | |||
T2533 | Alcaftadine | R89674,Lastacaft | Histamine Receptor |
Alcaftadine (Lastacaft) is an H1 histamine receptor antagonist indicated for the prevention of itching associated with allergic conjunctivitis. | |||
T1822L | Clemizole hydrochloride | HCV Protease , Histamine Receptor | |
Clemizole hydrochloride is an antagonist for H1 histamine receptor. According to the research, Clemizole hydrochloride can inhibit hepatitis C virus (HCV) replication and NS4B's RNA binding. | |||
T0865 | Ranitidine Hydrochloride | AH19065 | P450 , Antibacterial , Histamine Receptor |
Ranitidine Hydrochloride (AH19065) is a member of the class of histamine H2-receptor antagonists with antacid activity. Ranitidine is a competitive and reversible inhibitor of the action of histamine, released by enteroc... | |||
T1097 | Loratadine | SCH 29851,Loratidine | Influenza Virus , Histamine Receptor |
Loratadine (SCH 29851) is a second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central ne... | |||
T0053 | Hydroxyzine Pamoate | Hydroxyzine embonate,Bobsule,Equipose | Histamine Receptor |
Hydroxyzine Pamoate (Bobsule) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does ca... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0965 | Histamine | Ergamine | 5-HT Receptor , Endogenous Metabolite , Histamine Receptor |
Histamine (Ergamine) is an amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting ne... | |||
T20712 | Conessine | Conessinum,Wrightine,Roquessine,Neriine,Konessin | Histamine Receptor |
Conessine (Conessinum), a steroidal alkaloid isolated from Holarrhena floribunda, interacts with the histamine H3 receptor and has anti-malarial activity. | |||
T20884 | Hydroxyzine | Hydroxyzine free base | Histamine Receptor |
Hydroxyzine (Hydroxyzine free base) is an antagonist of histamine H1-receptor. | |||
T0330 | Diphenhydramine hydrochloride | Diphenhydramine HCl,DPH | Histamine Receptor |
Diphenhydramine hydrochloride (DPH) is a histamine H1 antagonist used as an antitussive and antiemetic. It is also used for pruritus and dermatoses, for hypersensitivity reactions, as an antiparkinson, a hypnotic, and as... | |||
TN1008 | Psoralenoside | CaMK , Calcium Channel , Histamine Receptor | |
Psoralenoside is a natural product isolated from the fruits of Psoralea corylifolia, shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity. | |||
T2520 | Desloratadine | Sch34117,NSC 675447 | Endogenous Metabolite , Histamine Receptor |
Desloratadine (Sch34117) is a long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic effects on H1-receptors in bronchial smoot... | |||
T19443 | N-Acetylhistamine | N-Omega-acetylhistamine | Endogenous Metabolite , Histamine Receptor |
N-Acetylhistamine (N-Omega-acetylhistamine) is a metabolite of histamine. | |||
T6535 | Histamine Phosphate | Histamine diphosphate,Histamine acid phosphate | Histamine Receptor |
Histamine Phosphate (Histamine acid phosphate) acts directly on the blood vessels to dilate arteries and capillaries mediated by both H 1- and H 2-receptors. | |||
T2848 | Osthole | Osthol,NSC 31868,Ostol | Apoptosis , HBV , Parasite , Histamine Receptor |
Osthole (Osthol), a potential inhibitor of histamine H1 receptor, has been shown to stimulate osteoblast proliferation and differentiation. | |||
T0783 | Mianserin hydrochloride | Mianserin HCl,Org GB 94,ORG GB-94 HCl | Dopamine Receptor , 5-HT Receptor , Opioid Receptor , Adrenergic Receptor , Histamine Receptor |
Mianserin hydrochloride (Org GB 94) is a tetracyclic compound with antidepressant effects. it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors. It may cause drowsiness and hematolog... | |||
T20597 | Alginic acid | Protanal LF,Snow acid algin G,Kelacid,Sazzio,Norgine | Apoptosis , Autophagy , Histamine Receptor |
Alginic acid (Snow acid algin G) is a natural polysaccharide extracted from brown seaweeds with anti-anaphylactic and anti-inflammatory activities. Alginic acid inhibits histamine release and can be used in the food indu... |
Cat No. | Product Name | Species | Expression System |
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TMPY-03054 | Fc epsilon RI Protein, Human, Recombinant (His) | Human | HEK293 |
FcERI, also known as FCER1A, is the alpha subunit of the immunoglobulin epsilon receptor (IgE receptor). IgE receptor is a high affinity IgE receptor which plays a central role in allergic disease, coupling allergen and ... | |||
TMPY-05084 | Fc epsilon RI Protein, Human, Recombinant | Human | HEK293 |
FcERI, also known as FCER1A, is the alpha subunit of the immunoglobulin epsilon receptor (IgE receptor). IgE receptor is a high affinity IgE receptor which plays a central role in allergic disease, coupling allergen and ... | |||
TMPY-05057 | Complement C5 Protein, Human, Recombinant (His & FLAG) | Human | HEK293 |
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway... | |||
TMPY-04902 | Complement C5a Protein, Mouse, Recombinant | Mouse | E. coli |
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway... | |||
TMPY-00653 | Complement C5 Protein, Human, Recombinant (Complement C5a) | Human | E. coli |
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway... | |||
TMPH-01236 | DFFB Protein, Human, Recombinant (His) | Human | E. coli |
Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. Plays an important role in the formation of functional inhibitory GABAergi... | |||
TMPH-01235 | APOBEC3A Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. Plays an important role in the formation of functional inhibitory GABAergi... | |||
TMPH-01476 | HDAC9 Protein, Human, Recombinant (His) | Human | E. coli |
Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Recognizes and binds small molecules ... | |||
TMPY-03064 | Fc epsilon RI Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
FcERI, also known as FCER1A, is the alpha subunit of the immunoglobulin epsilon receptor (IgE receptor). IgE receptor is a high affinity IgE receptor which plays a central role in allergic disease, coupling allergen and ... | |||
TMPH-02790 | MUSK Protein, Mouse, Recombinant (His & Myc & SUMO) | Mouse | E. coli |
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulat... | |||
TMPJ-00028 | CCL2 Protein, Mouse, Recombinant | Mouse | E. coli |
C-C motif chemokine 2 (CCL2) is a member of the C-C or β chemokine family. Mouse CCL2 shares 82% amino acid (aa) identity with rat CCL2 over the entire sequence, and 58%, 56%, 55%, 53% and 53% aa identity with human, equ... | |||
TMPY-06538 | Complement C5 Protein, Cynomolgus, Recombinant | Cynomolgus | HEK293 |
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway... | |||
TMPY-05459 | Complement C5a Protein, Mouse, Recombinant, Biotinylated | Mouse | E. coli |
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway... | |||
TMPY-06814 | Complement C5 Protein, Human, Recombinant (Flag) | Human | HEK293 |
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway... | |||
TMPY-06137 | Complement C5 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway... |
Cat No. | Product Name | ||
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L3300 | Histamine & Melatonin Receptor-Targeted Compound Library | 155 compounds | |
A unique collection of 155 compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS) for new drugs; |