T11756 |
Kgp-IN-1
|
2097865-36-4
|
98%
|
|
Kgp-IN-1 is an arginine-specific gingipain (Rgp) inhibitor.
|
T13745 |
KF21213
|
155271-17-3
|
98%
|
|
KF21213 shows a high affinity for the adenosine A2A receptors (Ki=3.0 nM). KF21213 is a highly selective ligand for mapping CNS adenosine A2A receptors.
|
T11880 |
LSD1-IN-5
|
2035912-55-9
|
98%
|
|
LSD1-IN-5 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1. LSD1-IN-5 is a potent and reversible inhibitor of lysine-specific de...
|
T16435 |
PBIT
|
2514-30-9
|
99.95%
|
|
PBIT inhibits JARID1B histone demethylase (IC50 of about 3 μM). PBIT also inhibits JARID1A and JARID1C (IC50s of 6 μM and 4.9 μM, respectively). PBIT is a specif...
|
T13055 |
T-3775440 hydrochloride
|
1422535-52-1
|
99.94%
|
|
T-3775440 hydrochloride is an irreversible inhibitor of lysine-specific histone demethylase (LSD1)(IC50 : 2.1 nM).
|
T9094 |
JMJD7-IN-1
|
311316-96-8
|
99.9%
|
|
JMJD7-IN-1 (Benzoic acid, 2,4-dichloro-, 5-nitro-8-quinolinyl ester) is a potent JMJD7 inhibitor, with an IC50 of 6.62 μM. JMJD7-IN-1 shows good inhibitory activ...
|
T3719 |
Daminozide
|
1596-84-5
|
99.88%
|
|
Daminozide (Succinic Acid) is a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily.
|
T67738 |
3-pyridine toxoflavin
|
32502-20-8
|
99.83%
|
|
3-pyridine toxoflavin is a potent KDM4C inhibitor, IC50=19nM.
|
T15650 |
KDM5A-IN-1
|
1905481-36-8
|
99.8%
|
|
KDM5A-IN-1 is an orally available, potent and selective inhibitor of the pan-histidine lysine demethylase 5 KDM5, inhibiting KDM5A, KDM5B, and KDM5C with IC50 va...
|
T4100 |
AS8351
|
796-42-9
|
99.72%
|
|
AS8351 (NSC51355) is a histone demethylase inhibitor. It has been used in combination with CHIR99021, A 83-01, BIX01294, SC-1, Y-27632, OAC2, SU 16f, and JNJ-101...
|
T6847 |
GSK-J1
|
1373422-53-7
|
99.67%
|
|
GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively, >...
|
T11748 |
KDM2A/7A-IN-1
|
2169272-46-0
|
99.59%
|
|
KDM2A/7A-IN-1 is a cell-permeable and selective inhibitor of the histone lysine demethylase KDM2A/7A with potential antitumor activity for the study of duodenal ...
|
T17211 |
Vafidemstat
|
1357362-02-7
|
99.53%
|
|
Vafidemstat (ORY-2001) is a selective, orally active lysyl-histone demethylase (LSD1)/MAO-B inhibitor that crosses the blood-brain barrier for the study of neuro...
|
T67871 |
LSD1-IN-24
|
4734-59-2
|
99.53%
|
|
LSD1-IN-24 is a selective and potent LSD1 inhibitor with an IC50 value of 0.247 μM.LSD1-IN-24 induces PD-L1 expression and enhances the T cell killing response, ...
|
T9243 |
PFI-90
|
53995-62-3
|
99.5%
|
|
PFI-90, a selective histone demethylase (KDM3B) inhibitor, targets PAX3-FOXO1 action and demonstrates potential antitumor activity. It induces apoptosis and myog...
|
T10983L |
DDP-38003 dihydrochloride
|
1831167-98-6
|
99.5%
|
|
DDP-38003 dihydrochloride is an orally available histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitor (IC50: 84 nM).
|
T2304 |
SP2509
|
1423715-09-6
|
99.49%
|
|
SP2509 is a specific histone demethylase LSD1 inhibitor(IC50 =13 nM).
|
T6922 |
ORY1001
|
1431326-61-2
|
99.4%
|
|
ORY1001 (ORY 1001) is an orally active and selective lysine-specific demethylase LSD1/KDM1A inhibitor, with high selectivity against related FAD dependent aminox...
|
T6545 |
IOX1
|
5852-78-8
|
99.38%
|
|
IOX1 is the most effective broad-spectrum 2OG oxygenases(including the JmjC demethylases) inhibitor. The IC50 of IOX1 for KDM4A, KDM3A, is 0.6 and 0.1 uM, respec...
|
T67781 |
SD49-7
|
54009-54-0
|
99.36%
|
|
SD49-7 is an inhibitor of histone lysine demethylase 4 (KDM4) with an IC50 of 0.19 µM.
|