T9581 |
ARRY-797
|
1034189-82-6
|
98.12%
|
|
ARRY-797 (ARRY-371797) is a potent and selective p38α inhibitor and inhibits LPS-Induced IL-6.
|
T3910 |
Pulchinenoside C
|
129741-57-7
|
98.04%
|
|
Pulchinenoside C (Anemoside B4) is an abundant triterpenoid saponin isolated from P. chinensis and exerts anti-inflammatory and antioxidant effects.
|
T5680 |
Aloin(mixture of A&B)
|
8015-61-0
|
98%
|
|
ALOIN Inhibits Interleukin (IL)-1β-Stimulated IL-8 Production in KB Cells.
|
T5779 |
MOSLOFLAVONE
|
740-33-0
|
98%
|
|
MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM, respectively.
|
T5660 |
Menthone
|
10458-14-7
|
98%
|
|
Menthone has anti-inflammary activity,, it can suppress the lipopolysaccharide (LPS)-induced proinflammatory cytokines, interleukin-1beta (IL-1beta) and tumor ne...
|
T6761 |
Ossirene
|
106566-58-9
|
98%
|
|
Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.
|
T0947 |
Dexamethasone acetate
|
1177-87-3
|
98%
|
|
Dexamethasone acetate (NSC 39471) is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addi...
|
TN6739 |
Angoline
|
21080-31-9
|
97.9%
|
|
Angoline (6-Methoxyldihydrochelerythrine) hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor(IC50 : 11.56 μM). It inhibits STAT3 phosp...
|
T60739L |
Y13g dihydrochloride
|
T60739L
|
97.81%
|
|
Y13g dihydrochloride is a potent inhibitor of interleukin 6 (IL-6) and acetylcholinesterase (AChE) (both targets of Alzheimer's disease (AD) progression are rela...
|
T5S0167 |
Atractylenolide I
|
73069-13-3
|
97.55%
|
|
1. Atractylenolide-I has an anti-inflammatory effect by inhibiting TNF-α and IL-6 production; ameliorates sepsis syndrome, liver and kidney functions by reductio...
|
T0117 |
Suplatast (Tosilate)
|
94055-76-2
|
97.47%
|
|
Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.
|
T8867 |
RO2959 Hydrochloride
|
1219927-22-6
|
97.42%
|
|
RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.
|
T36347 |
Ac-YVAD-CMK
|
178603-78-6
|
97.08%
|
|
Ac-YVAD-CMK (Ac-Tyr-Val-Ala-Asp-CMK) is a selective and irreversible inhibitor of Caspase-1 and inhibits pyroptosis, IL-1β and IL-18. Ac-YVAD-CMK shows neuroprot...
|
T14075 |
A-802715
|
107767-58-8
|
96.29%
|
|
A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the formation...
|
T21644L |
AF 12198 Acetate
|
T21644L
|
95.27%
|
|
AF 12198 Acetate is a novel low molecular weight antagonist of IL-1
|
T13666 |
Dupilumab
|
1190264-60-8
|
95.00%
|
|
Dupilumab (REGN-668) is a systemic immunomodulator for AD. Dupilumab is a fully human monoclonal antibody against the alpha subunit of the interleukin-4 receptor...
|
T38105 |
Ixekizumab
|
1143503-69-8
|
95.00%
|
|
Ixekizumab (LY2439821) is a humanized IgG4 monoclonal antibody that selectively binds and neutralizes interleukin IL-17A with a Kd value of <3 pM.Ixekizumab bloc...
|
TN1576 |
Diallyl disulfide
|
2179-57-9
|
95%
|
|
Diallyl disulfide has antitumor effect, the effect can be enhanced by miR-200b and miR-22.
|
T11179 |
Elubrixin
|
688763-64-6
|
100.00%
|
|
Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin can be used for inflammatory disea...
|
T23796 |
BIRT-377
|
213211-10-0
|
100%
|
|
BIRT-377 is a negative allosteric and orally bioavailable inhibitor of ICAM-1 and LFA-1(Ki = 25.8 nM). BIRT-377 inhibits the production of IL-2 and can be used i...
|