T62902 |
NDI-034858
|
2272904-53-5
|
100%
|
|
NDI-034858 (TAK-279) is a tyrosine kinase 2 (TYK2) inhibitor (Kd<200 pM) that targets the JH2 structural domain of Tyk2 for the treatment of autoimmune diseases ...
|
T77353 |
MyD88-IN-1
|
2911609-80-6
|
100%
|
|
MyD88-IN-1 is a potent MyD88 inhibitor MyD88-IN-1 has anti-inflammatory activity and inhibits downstream inflammatory signaling pathways, including the NF-κB pat...
|
TJS1779 |
Protosappanin A
|
102036-28-2
|
100%
|
|
Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inf...
|
T8828 |
CP 424174
|
210825-31-3
|
100%
|
|
CP 424174 is an inhibitor of IL-1β post-translational processing with IC50 of 210 nM. Inhibits the formation of mature IL-1β. Indirectly inhibits NLRP3. Active i...
|
T1246 |
Bornyl acetate
|
76-49-3
|
|
|
Bornyl acetate (Isobornyl acetate) has an anti-inflammatory effect. It is the volatile ingredient in some Chinese traditional herbs and numerous conifer oils.
|
T13375 |
YQ128
|
2454246-18-3
|
|
|
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
|
TP2008L |
Lyn peptide inhibitor acetate
|
TP2008L
|
|
|
Lyn peptide inhibitor acetate is a potent and cell-permeable inhibitor of Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact. Lyn pe...
|
T3280 |
Clodronate disodium tetrahydrate
|
88416-50-6
|
|
|
Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.
|
TN1983 |
Neoisoastilbin
|
54141-72-9
|
|
|
Neoisoastilbin may have antioxidant and anti-inflammatory activities.
|
TN1056 |
Mogroside IIe
|
88901-38-6
|
98%
|
|
Mogroside IIe is a bitter triterpenoid saponin which is the main component of unripe Luo Han Guo fruit and a precursor of the commercially available sweetener mo...
|
TQ0218 |
Deoxyandrographolide
|
79233-15-1
|
98%
|
|
Deoxyandrographolide (14-deoxyandrographolide) potentiates NGF-induced neurite outgrowth. Deoxyandrographolide suppresses the production of proinflammatory media...
|
TN4583 |
Moringin
|
73255-40-0
|
98%
|
|
Moringin is an isothiocyanate obtained from myrosinase-mediated hydrolysis of the glucosinolate precursor glucoMoringin present in Moringa oleifera seeds. Moring...
|
TN7236 |
Cephalandole B
|
915315-44-5
|
98%
|
|
cephalandole B, an indole alkaloid isolated from cyanide, significantly inhibited IL-17A gene expression and suppressed IL-17A luciferase reporter in Jukat cells...
|
TN1132 |
Procyanidin A2
|
41743-41-3
|
98%
|
|
Procyanidin A2 is a potential precursor of 5-(3',4'-dihydroxyphenyl)-γ-valerolactone, exhibits antioxidant, anti-inflammary, anti-hyperglycemia, and anti-type 2 ...
|
TC0036 |
Compound Lup-20(29)-en-3-yl acetate
|
TC0036
|
98%
|
|
Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.
|
T38362 |
Guselkumab
|
1350289-85-8
|
98%
|
|
Guselkumab (CNTO 1959) is a recombinant human IgG1 monoclonal antibody targeting the IL-23p19 subunit. Guselkumab binds to human cynomolgus monkey IL-23 with Kd ...
|
TN1403 |
Arjunolic acid
|
465-00-9
|
98%
|
|
Arjunolic acid has antioxidant, anti-inflammatory, antinociceptive and anticholinesterasic (AChE and BuChE) activities, it may as promising targets for the devel...
|
TN2539 |
1beta-Hydroxyalantolactone
|
68776-47-6
|
98%
|
|
1beta-Hydroxyalantolactone is a small molecular compound isolated from the flower head of the medicinal plant giant British flower, which can inhibit the express...
|
T34295 |
Resiniferatoxin
|
57444-62-9
|
98%
|
|
Resiniferatoxin ([3H]resiniferatoxin) inhibits the production of Th1 cytokines, contributing to the defense against T. spiralis infection, and can be used in stu...
|
T1347 |
2-Benzothiazolamine
|
136-95-8
|
98%
|
|
2-Benzothiazolamine (2-ABT) is a nitrogen-containing heterocyclic compound used as a reaction intermediate in the synthesis of a variety of drugs. It inhibits cy...
|