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Immunology / Inflammation Immunology & Inflammation related

Immunology & Inflammation related

Cat No. product name
T4122 TAPI-1 trifluoroacetate (171235-71-5(free base)) TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.
T6731 WYE-354 WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It blocks mTORC2/P-AKT(S473) and mTORC1/P-S6K(T389), not P-AKT(T308). The sele...
T4S1849 Tubeimoside III Tubeimoside III has anti-inflammatory, anti-tumor, and anti-tumorigenic activities, stronger than those of tubeimoside II.
T7522 GI 254023X GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s: 2.5 and 5.3 nM).
T8145 Benzyl cinnamate Benzyl cinnamate is a natural product isolated from various plant species,with anti-inflammatory activity.
TN1015 Meranzin Meranzin exhibits strong anti-inflammatory and analgesic activity.
TN1080 Kaji-ichigoside F1 Kaji-ichigoside F1 shows antiinflammatory/antinociceptive action in acetic acid-induced writhing and hot plate testing and in a carrageenan-induced paw edema mo...
TN1085 Dehydrotumulosic acid Dehydrotumulosic acid shows anti-inflammatory activity.
TN1111 Arnidiol Arnidiol has anti-inflammatory activity, it possesses marked inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice...
TN1144 Enmein Enmein shows significant inhibitory effect toward human tumor cell K562 with IC(50) values ranging from 3.2 microg/ml to 8.2 microg/ml
TN1166 1,3,6-Tri-O-galloylglucose 1,3,6-Tri-O-galloylglucose shows anti-inflammatory activity.
TN1249 3-Epiursolic acid 3-Epiursolic acid may have antiinflammatory activity, it shows inhibition on Cathepsins L (catL), the IC50 value of 6.5 μM, cathepsins L (catL) and B play an i...
TN1256 3-O-Acetyl-16 alpha-hydroxytrametenolic acid 3-O-Acetyl-16 alpha -hydroxytrametenolic acid has inhibitory activities against AAPH-induced hemolysis of red blood cells, it shows a strong inhibitory activity...
TN1355 Acanthoside B Acanthoside has inhibitory effects on the allergic inflammation.
TN1364 Ajugasterone C Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to carrageenan-induced inflammation in Sprague Dawley rat...
TN1402 Arjungenin Arjungenin shows α²-glucuronidase inhibitory activity, it shows antiviral, and anti-inflammatory activities.
TN1438 beta-Amyrin acetate beta-Amyrin acetate has anti-inflammatory, antioxidant, and antidyslipidemic activities, it shows significant HMG-CoA-reductase and sEH inhibition.
TN1455 Bryodulcosigenin Bryodulcosigenin has anti-inflammatory effect, it shows potent inhibitory effects on EBV-EA induction.
TN1563 Dehydropachymic acid Dehydropachymic acid shows antiinflammatory activity.
TN1590 DL-alpha-Tocopherylacetate Dl-alpha-tocopheryl acetate is a dietary supplement.
TN1608 (-)-Epigallocatechin-3-(3''-O-methyl) gallate (-)-Epigallocatechin-3-(3''-O-methyl)gallate shows antioxidative, cytotoxic, antiallergic, and anti-inflammatory activities, it can negatively regulate basophil...
TN1697 Glucosyringic acid Glucosyringic acid has immunosuppressive effect, it can inhibit the proliferation of murine B lymphocytes in vitro.
TN1730 Heraclenol Heraclenol is a germination inhibitor in the parsley seeds. It has anti-inflammatory properties against the ear edema in mice produced by TPA. Heraclenol and he...
TN1782 Isolariciresinol Isolariciresinol has antioxidant and anti-inflammatory activities during an in vitro gastro-intestinal digestion of the Radix Isatidis extract (RIE).
TN1823 Kaempferol-3-O-galactoside Kaempferol-3-O-α²-d-galactoside has antioxidant, anti-inflammatory and antinociceptive activities.
TN1961 Myricetin 3-O-beta-D-glucopyranoside Myricetin 3-O-beta-D-glucopyranoside may have antioxidant, and anti-inflammatory activities.
TN2022 Oxoglaucine Oxoglaucine exerts immunomodulatory effect in vivo in a dose-dependent and protocol-dependent manner, it also exhibits significant antiplatelet aggregation acti...
TN2159 Robustine Robustine may have anti-inflammatory activity, it exhibits inhibition (IC 50 < or = 18.19 microM) of superoxide anion generation by human neutrophils in respons...
TN2287 Turkesterone Turkesterone is a phytoecdysteroid possessing an 11alpha-hydroxyl group, also is an analogue of the insect steroid hormone 20-hydroxyecdysone. It has immunomodu...
TN1133 Isocolumbin Isocolumbin has anti-inflammatory, and antimicrobial activities.
TN1506 Clemastanin B Clemastanin B has antioxidant and anti-inflammatory activities, it exerts its anti-influenza activity by inhibiting the virus multiplication, prophylaxsis and b...
TN1661 Ganoderic acid C2 Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on ...
TN2045 Pelargonidin-3-O-glucoside chloride Pelargonidin-3-O-glucopyranoside is the glucoside of Pelargonidin, an potential antidiabetic agent. Pelargonidin-3-O-glucopyranoside has antioxidant, anti-infla...
TN2283 Tripterifordin Tripterifordin shows anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 1 microgram/ml.
TN2308 Wilfortrine Wilfortrine can induce liver cancer cell HepG2 apoptosis, but with no effect on the cell cycle, mainly by promoting Bax expression and inhibiting anti-apoptotic...
TN1923 Mesaconine Mesaconine has cardiac effect, it also has anti-NF-κB activity. Mesaconine may be part of material basis of Mahuang Fuzi Xixin decoction on anti-inflammation a...
TN2316 Xanthyletin Xanthyletin has anti-inflammatory, anti-tumor and anti-bacterial activities, it also inhibits symbiotic fungus cultivated by leaf-cutting ants.
T2S1334 Daphnetin 7-methyl ether Daphnetin 7-methyl ether has anti-inflammatory activity.
T3832 11-O-Galloylbergenin 11-O-Galloylbergenin shows good antioxidant and antiplasmodial activities, it shows significant analgesic activity at doses of 20 and 40 mg/kg against formalin ...
T3834 8-Epideoxyloganic acid 8-Epideoxyloganic acid possesses bioactivities of analgesia, homeostasis and anti-inflammatory. It has the potential to serve as anti-inflammatory agents during...
T3S0289 Araloside X Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the am...
T4S0818 Chasmanine Chasmanine, hypaconitine, and deoxyaconitine are anti-inflammatory pharmacodynamic components in Heishunpian (HSP) with positive relations with HSP efficacy. Ch...
T4S1472 Cucurbitacin S Cucurbitacins from Wilbrandia ebracteata have analgesic effects. Cucurbitacin S has anticancer and antiinflammatory activities.
TL0013 Heraclenin Heraclenin has anticoagulant, and anti-inflammatory activities, it also has mutagenicity in Chlamydomonas reinhardii. Heraclenin can induce apoptosis in Jurkat ...
TN2766 2'-Hydroxydaidzein 2'-Hydroxygenistein is an isoflavonoid phytoalexin, it suppresses chemical mediators in inflammatory cells, may have value in treatment and prevention of centra...
TN2792 2-Oxopomolic acid 2-Oxopomolic acid shows cytotoxic activity, it shows a significant decrease in intracellular melanin content in B16-F10 cells, and in culture media melanin. 2-O...
TN2928 3-Epicorosolic acid 3-Epicorosolic acid has a potent inhibitory effect on Epstein-Barr virus early antigen (EBV-EA) induction, it has potential anti-inflammatory activities as well...
TMA2008 3-Hydroxy-1,5-diphenyl-1-pentanone (+)-3-Hydroxy-1,5-diphenyl-1-pentanone exhibits both immunomodulatory and anti-tumor activity.
TN2973 3'-O-Methylmurraol 3'-O-Methylmurraol may have potential anti-inflammatory activity, it exhibits inhibition (IC50 ≤ 7.31 ug/mL) of superoxide anion generation by human neutrophi...
TN3395 Alpinone 3-acetate Alpinone 3-acetate has anti-inflammatory activity, it can inhibit 12-O-tetradecanoyiphorbol 13-acetate-induced inflammation in a mouse model of ear edema.
TAPI-1 trifluoroacetate (171235-71-5(free base))
T4122CAS T4122
TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.
WYE-354
T6731CAS 1062169-56-5
WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It blocks mTORC2/P-AKT(S473) and mTORC1/P-S6K(T389), not P-AKT(T308). The sele...
Tubeimoside III
T4S1849CAS 115810-13-4
Tubeimoside III has anti-inflammatory, anti-tumor, and anti-tumorigenic activities, stronger than those of tubeimoside II.
GI 254023X
T7522CAS 260264-93-5
GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s: 2.5 and 5.3 nM).
Benzyl cinnamate
T8145CAS 103-41-3
Benzyl cinnamate is a natural product isolated from various plant species,with anti-inflammatory activity.
Meranzin
TN1015CAS 23971-42-8
Meranzin exhibits strong anti-inflammatory and analgesic activity.
Kaji-ichigoside F1
TN1080CAS 95298-47-8
Kaji-ichigoside F1 shows antiinflammatory/antinociceptive action in acetic acid-induced writhing and hot plate testing and in a carrageenan-induced paw edema mo...
Dehydrotumulosic acid
TN1085CAS 6754-16-1
Dehydrotumulosic acid shows anti-inflammatory activity.
Arnidiol
TN1111CAS 6750-30-7
Arnidiol has anti-inflammatory activity, it possesses marked inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice...
Enmein
TN1144CAS 3776-39-4
Enmein shows significant inhibitory effect toward human tumor cell K562 with IC(50) values ranging from 3.2 microg/ml to 8.2 microg/ml
1,3,6-Tri-O-galloylglucose
TN1166CAS 18483-17-5
1,3,6-Tri-O-galloylglucose shows anti-inflammatory activity.
3-Epiursolic acid
TN1249CAS 989-30-0
3-Epiursolic acid may have antiinflammatory activity, it shows inhibition on Cathepsins L (catL), the IC50 value of 6.5 μM, cathepsins L (catL) and B play an i...
3-O-Acetyl-16 alpha-hydroxytrametenolic acid
TN1256CAS 168293-13-8
3-O-Acetyl-16 alpha -hydroxytrametenolic acid has inhibitory activities against AAPH-induced hemolysis of red blood cells, it shows a strong inhibitory activity...
Acanthoside B
TN1355CAS 7374-79-0
Acanthoside has inhibitory effects on the allergic inflammation.
Ajugasterone C
TN1364CAS 23044-80-6
Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to carrageenan-induced inflammation in Sprague Dawley rat...
Arjungenin
TN1402CAS 58880-25-4
Arjungenin shows α²-glucuronidase inhibitory activity, it shows antiviral, and anti-inflammatory activities.
beta-Amyrin acetate
TN1438CAS 1616-93-9
beta-Amyrin acetate has anti-inflammatory, antioxidant, and antidyslipidemic activities, it shows significant HMG-CoA-reductase and sEH inhibition.
Bryodulcosigenin
TN1455CAS 4965-97-3
Bryodulcosigenin has anti-inflammatory effect, it shows potent inhibitory effects on EBV-EA induction.
Dehydropachymic acid
TN1563CAS 77012-31-8
Dehydropachymic acid shows antiinflammatory activity.
DL-alpha-Tocopherylacetate
TN1590CAS 7695-91-2
Dl-alpha-tocopheryl acetate is a dietary supplement.
(-)-Epigallocatechin-3-(3''-O-methyl) gallate
TN1608CAS 83104-87-4
(-)-Epigallocatechin-3-(3''-O-methyl)gallate shows antioxidative, cytotoxic, antiallergic, and anti-inflammatory activities, it can negatively regulate basophil...
Glucosyringic acid
TN1697CAS 33228-65-8
Glucosyringic acid has immunosuppressive effect, it can inhibit the proliferation of murine B lymphocytes in vitro.
Heraclenol
TN1730CAS 31575-93-6
Heraclenol is a germination inhibitor in the parsley seeds. It has anti-inflammatory properties against the ear edema in mice produced by TPA. Heraclenol and he...
Isolariciresinol
TN1782CAS 548-29-8
Isolariciresinol has antioxidant and anti-inflammatory activities during an in vitro gastro-intestinal digestion of the Radix Isatidis extract (RIE).
Kaempferol-3-O-galactoside
TN1823CAS 23627-87-4
Kaempferol-3-O-α²-d-galactoside has antioxidant, anti-inflammatory and antinociceptive activities.
Myricetin 3-O-beta-D-glucopyranoside
TN1961CAS 19833-12-6
Myricetin 3-O-beta-D-glucopyranoside may have antioxidant, and anti-inflammatory activities.
Oxoglaucine
TN2022CAS 5574-24-3
Oxoglaucine exerts immunomodulatory effect in vivo in a dose-dependent and protocol-dependent manner, it also exhibits significant antiplatelet aggregation acti...
Robustine
TN2159CAS 2255-50-7
Robustine may have anti-inflammatory activity, it exhibits inhibition (IC 50 < or = 18.19 microM) of superoxide anion generation by human neutrophils in respons...
Turkesterone
TN2287CAS 41451-87-0
Turkesterone is a phytoecdysteroid possessing an 11alpha-hydroxyl group, also is an analogue of the insect steroid hormone 20-hydroxyecdysone. It has immunomodu...
Isocolumbin
TN1133CAS 471-54-5
Isocolumbin has anti-inflammatory, and antimicrobial activities.
Clemastanin B
TN1506CAS 112747-98-5
Clemastanin B has antioxidant and anti-inflammatory activities, it exerts its anti-influenza activity by inhibiting the virus multiplication, prophylaxsis and b...
Ganoderic acid C2
TN1661CAS 103773-62-2
Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on ...
Pelargonidin-3-O-glucoside chloride
TN2045CAS 18466-51-8
Pelargonidin-3-O-glucopyranoside is the glucoside of Pelargonidin, an potential antidiabetic agent. Pelargonidin-3-O-glucopyranoside has antioxidant, anti-infla...
Tripterifordin
TN2283CAS 139122-81-9
Tripterifordin shows anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 1 microgram/ml.
Wilfortrine
TN2308CAS 37239-48-8
Wilfortrine can induce liver cancer cell HepG2 apoptosis, but with no effect on the cell cycle, mainly by promoting Bax expression and inhibiting anti-apoptotic...
Mesaconine
TN1923CAS 6792-09-2
Mesaconine has cardiac effect, it also has anti-NF-κB activity. Mesaconine may be part of material basis of Mahuang Fuzi Xixin decoction on anti-inflammation a...
Xanthyletin
TN2316CAS 553-19-5
Xanthyletin has anti-inflammatory, anti-tumor and anti-bacterial activities, it also inhibits symbiotic fungus cultivated by leaf-cutting ants.
Daphnetin 7-methyl ether
T2S1334CAS 19492-03-6
Daphnetin 7-methyl ether has anti-inflammatory activity.
11-O-Galloylbergenin
T3832CAS 82958-44-9
11-O-Galloylbergenin shows good antioxidant and antiplasmodial activities, it shows significant analgesic activity at doses of 20 and 40 mg/kg against formalin ...
8-Epideoxyloganic acid
T3834CAS 88668-99-9
8-Epideoxyloganic acid possesses bioactivities of analgesia, homeostasis and anti-inflammatory. It has the potential to serve as anti-inflammatory agents during...
Araloside X
T3S0289CAS 344911-90-6
Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the am...
Chasmanine
T4S0818CAS 5066-78-4
Chasmanine, hypaconitine, and deoxyaconitine are anti-inflammatory pharmacodynamic components in Heishunpian (HSP) with positive relations with HSP efficacy. Ch...
Cucurbitacin S
T4S1472CAS 60137-06-6
Cucurbitacins from Wilbrandia ebracteata have analgesic effects. Cucurbitacin S has anticancer and antiinflammatory activities.
Heraclenin
TL0013CAS 2880-49-1
Heraclenin has anticoagulant, and anti-inflammatory activities, it also has mutagenicity in Chlamydomonas reinhardii. Heraclenin can induce apoptosis in Jurkat ...
2'-Hydroxydaidzein
TN2766CAS 7678-85-5
2'-Hydroxygenistein is an isoflavonoid phytoalexin, it suppresses chemical mediators in inflammatory cells, may have value in treatment and prevention of centra...
2-Oxopomolic acid
TN2792CAS 54963-52-9
2-Oxopomolic acid shows cytotoxic activity, it shows a significant decrease in intracellular melanin content in B16-F10 cells, and in culture media melanin. 2-O...
3-Epicorosolic acid
TN2928CAS 52213-27-1
3-Epicorosolic acid has a potent inhibitory effect on Epstein-Barr virus early antigen (EBV-EA) induction, it has potential anti-inflammatory activities as well...
3-Hydroxy-1,5-diphenyl-1-pentanone
TMA2008CAS 60669-64-9
(+)-3-Hydroxy-1,5-diphenyl-1-pentanone exhibits both immunomodulatory and anti-tumor activity.
3'-O-Methylmurraol
TN2973CAS 1891097-17-8
3'-O-Methylmurraol may have potential anti-inflammatory activity, it exhibits inhibition (IC50 ≤ 7.31 ug/mL) of superoxide anion generation by human neutrophi...
Alpinone 3-acetate
TN3395CAS 139906-49-3
Alpinone 3-acetate has anti-inflammatory activity, it can inhibit 12-O-tetradecanoyiphorbol 13-acetate-induced inflammation in a mouse model of ear edema.