| T4122 |
TAPI-1 trifluoroacetate (171235-71-5(free base)) |
TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors. |
| T6731 |
WYE-354 |
WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It blocks mTORC2/P-AKT(S473) and mTORC1/P-S6K(T389), not P-AKT(T308). The sele...
|
| T4S1849 |
Tubeimoside III |
Tubeimoside III has anti-inflammatory, anti-tumor, and anti-tumorigenic activities, stronger than those of tubeimoside II. |
| T7522 |
GI 254023X |
GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s: 2.5 and 5.3 nM). |
| T8145 |
Benzyl cinnamate |
Benzyl cinnamate is a natural product isolated from various plant species,with anti-inflammatory activity. |
| TN1015 |
Meranzin |
Meranzin exhibits strong anti-inflammatory and analgesic activity. |
| TN1080 |
Kaji-ichigoside F1 |
Kaji-ichigoside F1 shows antiinflammatory/antinociceptive action in acetic acid-induced writhing and hot plate testing and in a carrageenan-induced paw edema mo...
|
| TN1085 |
Dehydrotumulosic acid |
Dehydrotumulosic acid shows anti-inflammatory activity. |
| TN1111 |
Arnidiol |
Arnidiol has anti-inflammatory activity, it possesses marked inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice...
|
| TN1144 |
Enmein |
Enmein shows significant inhibitory effect toward human tumor cell K562 with IC(50) values ranging from 3.2 microg/ml to 8.2 microg/ml |
| TN1166 |
1,3,6-Tri-O-galloylglucose |
1,3,6-Tri-O-galloylglucose shows anti-inflammatory activity. |
| TN1249 |
3-Epiursolic acid |
3-Epiursolic acid may have antiinflammatory activity, it shows inhibition on Cathepsins L (catL), the IC50 value of 6.5 μM, cathepsins L (catL) and B play an i...
|
| TN1256 |
3-O-Acetyl-16 alpha-hydroxytrametenolic acid |
3-O-Acetyl-16 alpha -hydroxytrametenolic acid has inhibitory activities against AAPH-induced hemolysis of red blood cells, it shows a strong inhibitory activity...
|
| TN1355 |
Acanthoside B |
Acanthoside has inhibitory effects on the allergic inflammation. |
| TN1364 |
Ajugasterone C |
Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to carrageenan-induced inflammation in Sprague Dawley rat...
|
| TN1402 |
Arjungenin |
Arjungenin shows α²-glucuronidase inhibitory activity, it shows antiviral, and anti-inflammatory activities. |
| TN1438 |
beta-Amyrin acetate |
beta-Amyrin acetate has anti-inflammatory, antioxidant, and antidyslipidemic activities, it shows significant HMG-CoA-reductase and sEH inhibition. |
| TN1455 |
Bryodulcosigenin |
Bryodulcosigenin has anti-inflammatory effect, it shows potent inhibitory effects on EBV-EA induction. |
| TN1563 |
Dehydropachymic acid |
Dehydropachymic acid shows antiinflammatory activity. |
| TN1590 |
DL-alpha-Tocopherylacetate |
Dl-alpha-tocopheryl acetate is a dietary supplement. |
| TN1608 |
(-)-Epigallocatechin-3-(3''-O-methyl) gallate |
(-)-Epigallocatechin-3-(3''-O-methyl)gallate shows antioxidative, cytotoxic, antiallergic, and anti-inflammatory activities, it can negatively regulate basophil...
|
| TN1697 |
Glucosyringic acid |
Glucosyringic acid has immunosuppressive effect, it can inhibit the proliferation of murine B lymphocytes in vitro. |
| TN1730 |
Heraclenol |
Heraclenol is a germination inhibitor in the parsley seeds. It has anti-inflammatory properties against the ear edema in mice produced by TPA. Heraclenol and he...
|
| TN1782 |
Isolariciresinol |
Isolariciresinol has antioxidant and anti-inflammatory activities during an in vitro gastro-intestinal digestion of the Radix Isatidis extract (RIE). |
| TN1823 |
Kaempferol-3-O-galactoside |
Kaempferol-3-O-α²-d-galactoside has antioxidant, anti-inflammatory and antinociceptive activities. |
| TN1961 |
Myricetin 3-O-beta-D-glucopyranoside |
Myricetin 3-O-beta-D-glucopyranoside may have antioxidant, and anti-inflammatory activities. |
| TN2022 |
Oxoglaucine |
Oxoglaucine exerts immunomodulatory effect in vivo in a dose-dependent and protocol-dependent manner, it also exhibits significant antiplatelet aggregation acti...
|
| TN2159 |
Robustine |
Robustine may have anti-inflammatory activity, it exhibits inhibition (IC 50 < or = 18.19 microM) of superoxide anion generation by human neutrophils in respons...
|
| TN2287 |
Turkesterone |
Turkesterone is a phytoecdysteroid possessing an 11alpha-hydroxyl group, also is an analogue of the insect steroid hormone 20-hydroxyecdysone. It has immunomodu...
|
| TN1133 |
Isocolumbin |
Isocolumbin has anti-inflammatory, and antimicrobial activities. |
| TN1506 |
Clemastanin B |
Clemastanin B has antioxidant and anti-inflammatory activities, it exerts its anti-influenza activity by inhibiting the virus multiplication, prophylaxsis and b...
|
| TN1661 |
Ganoderic acid C2 |
Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on ...
|
| TN2045 |
Pelargonidin-3-O-glucoside chloride |
Pelargonidin-3-O-glucopyranoside is the glucoside of Pelargonidin, an potential antidiabetic agent. Pelargonidin-3-O-glucopyranoside has antioxidant, anti-infla...
|
| TN2283 |
Tripterifordin |
Tripterifordin shows anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 1 microgram/ml. |
| TN2308 |
Wilfortrine |
Wilfortrine can induce liver cancer cell HepG2 apoptosis, but with no effect on the cell cycle, mainly by promoting Bax expression and inhibiting anti-apoptotic...
|
| TN1923 |
Mesaconine |
Mesaconine has cardiac effect, it also has anti-NF-κB activity. Mesaconine may be part of material basis of Mahuang Fuzi Xixin decoction on anti-inflammation a...
|
| TN2316 |
Xanthyletin |
Xanthyletin has anti-inflammatory, anti-tumor and anti-bacterial activities, it also inhibits symbiotic fungus cultivated by leaf-cutting ants. |
| T2S1334 |
Daphnetin 7-methyl ether |
Daphnetin 7-methyl ether has anti-inflammatory activity. |
| T3832 |
11-O-Galloylbergenin |
11-O-Galloylbergenin shows good antioxidant and antiplasmodial activities, it shows significant analgesic activity at doses of 20 and 40 mg/kg against formalin ...
|
| T3834 |
8-Epideoxyloganic acid |
8-Epideoxyloganic acid possesses bioactivities of analgesia, homeostasis and anti-inflammatory. It has the potential to serve as anti-inflammatory agents during...
|
| T3S0289 |
Araloside X |
Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the am...
|
| T4S0818 |
Chasmanine |
Chasmanine, hypaconitine, and deoxyaconitine are anti-inflammatory pharmacodynamic components in Heishunpian (HSP) with positive relations with HSP efficacy. Ch...
|
| T4S1472 |
Cucurbitacin S |
Cucurbitacins from Wilbrandia ebracteata have analgesic effects. Cucurbitacin S has anticancer and antiinflammatory activities. |
| TL0013 |
Heraclenin |
Heraclenin has anticoagulant, and anti-inflammatory activities, it also has mutagenicity in Chlamydomonas reinhardii. Heraclenin can induce apoptosis in Jurkat ...
|
| TN2766 |
2'-Hydroxydaidzein |
2'-Hydroxygenistein is an isoflavonoid phytoalexin, it suppresses chemical mediators in inflammatory cells, may have value in treatment and prevention of centra...
|
| TN2792 |
2-Oxopomolic acid |
2-Oxopomolic acid shows cytotoxic activity, it shows a significant decrease in intracellular melanin content in B16-F10 cells, and in culture media melanin. 2-O...
|
| TN2928 |
3-Epicorosolic acid |
3-Epicorosolic acid has a potent inhibitory effect on Epstein-Barr virus early antigen (EBV-EA) induction, it has potential anti-inflammatory activities as well...
|
| TMA2008 |
3-Hydroxy-1,5-diphenyl-1-pentanone |
(+)-3-Hydroxy-1,5-diphenyl-1-pentanone exhibits both immunomodulatory and anti-tumor activity. |
| TN2973 |
3'-O-Methylmurraol |
3'-O-Methylmurraol may have potential anti-inflammatory activity, it exhibits inhibition (IC50 ≤ 7.31 ug/mL) of superoxide anion generation by human neutrophi...
|
| TN3395 |
Alpinone 3-acetate |
Alpinone 3-acetate has anti-inflammatory activity, it can inhibit 12-O-tetradecanoyiphorbol 13-acetate-induced inflammation in a mouse model of ear edema. |
| TN3403 |
Alternariol monomethyl ether |
Alternariol monomethyl ether,an Alternaria toxin, is a strong mutagen in Escherichia coli strain ND-160. Alternariol monomethyl ether has genotoxic properties, ...
|
| TN3447 |
Arjunglucoside I |
Arjunglucoside I has anti-inflammatory activity, it exhibits significant activity against carrageenan-induced paw edema in rat. It also shows antiproliferative ...
|
| TN3473 |
Axillarin |
Axillarin has antioxidant activity, it shows xanthine oxidase inhibitory activity ( IC(50) :36.0 uM). Axillarin can strongly protect primary cultured neurons ag...
|
| TN3576 |
Cannabisin F |
Melongenamides B-D and Cannabisin F have anti-inflammatory activity, they exhibit inhibitions of nitric oxide production in lipopolysaccharide-induced RAW 264.7...
|
| TN3706 |
Coronarin A |
Coronarin, A, B, C, and D are cytotoxic prinicples from the rhizomes of Hedychium coronarium, Zingiberaceae. Coronarin A exhibits good growth inhibition activit...
|
| TN3725 |
Cucurbitadienol |
Cucurbitadienol has significant anti-inflammatory, anti-tumor effect, is also CucurbitacinBE compounds biosynthesis the key intermediate. Cucurbitadienol syntha...
|
| TN3815 |
Delta 7-avenasterol |
Delta 7-avenasterol has antioxidant activity. |
| TN3879 |
Docosyl caffeate |
Docosyl caffeate shows moderate antioxidant activity in DPPH and ABTS scavenging assays, it also has significant anti-inflammation activity. Docosyl caffeate ex...
|
| TN4045 |
Evofolin C |
Evofolin C and its acetate show strong antifungal and antibacterial activity. Evofolin C exhibits potent inhibition against N-formylmethionylleucylphenylalanine...
|
| TN4103 |
Ganoderic acid K |
Ganoderic acid K is an angiotensin-converting enzyme inhibitor. It has anti-tumor, and anti-inflammatory activities. |
| TN4132 |
Germanicol |
Germanicol induces selective growth inhibitory effects in human colon HCT-116 and HT29 cancer cells through induction of apoptosis, cell cycle arrest and inhibi...
|
| TN4185 |
Hautriwaic acid |
Hautriwaic acid shows anti-inflammatory activity in 12-O-tetradecanoylphorbol 13-acetate (TPA) mice ear edema models, it diminishes the joint edema induced by t...
|
| TN4189 |
Hedychenone |
Hedychenone has anti-inflammatory activity, it also shows potent in vitro cytotoxic activity against cancerous cells. |
| TN4214 |
Hispanone |
Hispanone possesses anti-inflammatory activity, it shows inhibition of superoxide anion generation and elastase release. |
| TN4241 |
Hyptadienic acid |
Hyptadienic acid exhibits moderate cytotoxicity against HepG2 cells.It also shows a marked anti-inflammatory effect, it also exhibits strong antitumor-promoting...
|
| TN4388 |
Kielcorin |
Kielcorin shows antibacterial activity against strain EMRSA-16. It also shows in vitro anti-inflammatory (respiratory burst) inhibiting activities using isolate...
|
| TN4406 |
Lamiide |
Lamiide has anti-inflammatory activity in carrageenin-induced paw edema test. It shows lipid peroxidation inhibition on rat-brain phospholipid peroxidation. |
| TN4493 |
Mannioside A |
Mannioside A has anti-inflammatory activity, inhibits carrageenan-induced paw edema in the rat. |
| TN4506 |
(+)-Matairesinol |
(+)-Matairesinol exhibits immunomodulatory activity; it also shows inhibition of the discoloration of yellowtail dark muscle. |
| TN4529 |
Methyl 3-carbazolecarboxylate |
Methyl 3-carbazolecarboxylate is a natural product from Micromelum sp. |
| TN4659 |
Nimbin |
Nimbin is an anti-pyretic, can be used to treat arthritis, hypoglycaemia, peptic ulcers, anti-secretory activity, and it can also be used as an antibiotic. Nimb...
|
| TN4771 |
Phyltetralin |
Phyltetralin has antihyperuricemic activity. |
| TN4804 |
Platycoside A |
Platycoside A has hemolytic activity and adjuvant potential on the immune responses to Newcastle disease virus-based recombinant avian influenza vaccine. It ind...
|
| TN4811 |
Plumieride |
Plumieride has plant growth inhibiting properties, it shows strong fungitoxicity against some dermatophytes causing dermatomycosis to animals and human beings. ...
|
| TN4831 |
Procumbide |
Procumbide has anti-inflammatory activity. |
| TN4838 |
Pseurotin A |
Pseurotin A has immunosuppressive activity, it inhibits immunoglobulin E(IgE) production in vitro.It shows a moderate effect against the phytopathogenic bacteri...
|
| TN4841 |
Ptaquiloside |
Ptaquiloside shows genotoxicity, it also has carcinogenic effects. Ptaquiloside has immunosuppressive effects, it reduces NK cell activities by enhancing metall...
|
| TN4921 |
Rubelloside B |
Rubelloside B exhibits immunological enhancement effect. |
| TN4967 |
Scoparinol |
Scoparinol has sedative, anti-inflammatory, analgesic, and diuretic actions. |
| TN5062 |
Stigmast-4-ene-3,6-dione |
Stigmast-4-ene-3,6-dione has anti-inflammatory and anti-allergic properties. |
| TN5069 |
Stigmastane-3,6-dione |
Stigmastane-3,6-dione has anti-inflammatory activity. 5 alpha-Stigmastane-3,6-dione shows antifeedant activity against bell weevils. |
| TMA0627 |
Taxiresinol |
Taxiresinol shows anticancer, antinociceptive, and antiallergic activities, it shows inhibitory activity on induced histamine release from the human basophilic ...
|
| TN5151 |
Tomentin |
Tomentin has anti-inflammatory effects, it can inhibit the formation of λ-carrageenan footpad edema at 58%. |
| TMA2235 |
Triptobenzene H |
Triptobenzene H shows the significant immunosuppressive activity. |
| TN5221 |
(-)-Variabilin |
Variabilin, a novel inhibitor of human platelet aggregation, it is a potent RGD (Arg-Gly-Asp)-containing antagonist of the fibrinogen receptor glycoprotein IIb-...
|
| TN5223 |
Vasicinolone |
Vasicinolone has anti-inflammatory, and antimicrobial activities. |
| TN5227 |
(+/-)-Vestitol |
Vestitol has antioxidation, anti-inflammatory and antimicrobial activities, it can strongly act in a low dose and concentration and have a promising potential t...
|
| TN5228 |
Vestitol |
Vestitol is a phytoalexin with insect feeding-deterrent activity, it has antioxidant, anti-inflammatory and antimicrobial activities, it can inhibit neutrophil ...
|
| TN5262 |
Wittifuran X |
Wittifuran X has antioxidant and anti-inflammatory activities. |
| TN5280 |
Zeylenol |
(-)-Zeylenol shows antifeedant activity. Zeylenol shows inhibitory activity toward the root growth of Lactuca sativa. Zeylenol probably possesses anti-inflammat...
|
