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Integrin

Integrins are proteins that function mechanically, by attaching the cell cytoskeleton to the extracellular matrix (ECM), and biochemically, by sensing whether adhesion has occurred. The integrin family of proteins consists of alpha and beta subtypes, which form transmembrane heterodimers.

Cat. No.	Product name	CAS No.	Purity
T13478	β-glycosidase-IN-1	176485-27-1	98%
T13478	β-glycosidase-IN-1 is a piperidine derivative, and is an inhibitor of β-glycosidase. It has hypoglycemic activity.
T29089	Valategrast hydrochloride	828271-96-1	98%
T29089	Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.
T16100	Balamapimod	863029-99-6	98%
T16100	Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.
T6806	Cilengitide TFA	199807-35-7	98%
T6806	Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectiv...
T40960	Fibronectin	86088-83-7	98%
T40960	Fibronectin is a macromolecular glycoprotein found in blood, connective tissue, and cell surfaces that serves as a biomarker for tissue damage.Fibronectin is rec...
T14573	Bimosiamose disodium	187269-60-9	98%
T14573	Bimosiamose disodium has anti-inflammatory effects[1]. Bimosiamose disodium (TBC-1269Z) is a nonoligosaccharide pan-selectin inhibitor with IC50s of 88 μM, 20 μM...
T6657	SB273005	205678-31-5	98%
T6657	SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.
T14574	Bimosiamose	187269-40-5	98%
T14574	Bimosiamose has anti-inflammatory effects[1]. Bimosiamose (TBC-1269) is a nonoligosaccharide pan-selectin antagonist with IC50s of 88 μM, 20 μM, and 86 μM for E-...
T3881	Vaccarin	53452-16-7	99.97%
T3881	Vaccarin is a major flavonoid glycoside in Vaccariae semen, its biotransformation pathways involves methylation, hydroxylation, glycosylation and deglycosylation...
T41151L	K34c hydrochloride		99.95%
T41151L	K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.
T27250	Elarofiban	198958-88-2	99.94%
T27250	Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.
T8523	ILK-IN-3	6975-75-3	99.88%
T8523	ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.
T6182	Tirofiban	144494-65-5	99.87%
T6182	Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.
TN1244	3'-Demethylnobiletin	112448-39-2	99.87%
TN1244	3'-Demethylnobiletin has chemopreventive effects on colon carcinogenesis, it can significantly inhibit the growth of human colon cancer cells, cause cell-cycle a...
T2537	Tirofiban hydrochloride monohydrate	150915-40-5	99.86%
T2537	Tirofiban hydrochloride monohydrate (MK-383 Hydrochloride) is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist.
T6812	Cyclo(-RGDfK)	161552-03-0	99.83%
T6812	Cyclo(-RGDfK) (Cyclo (-RGDfK)) is an effective and specific αvβ3 integrin inhibitor.
TP1459L	Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base)	TP1459L	99.81%
TP1459L	Gly-Arg-Gly-Asp-Ser (GRGDS) acetate is a cell binding protein domain derived from the cell-binding region of fibronectin.
T5310	TR-14035	232271-19-1	99.81%
T5310	TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).
T2494	Cilengitide	188968-51-6	99.8%
T2494	Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.
TP1290	GRGDSP acetate(91037-75-1 free base)	TP1290	99.77%
TP1290	GRGDSP acetate(91037-75-1 free base) is a synthetic linear RGD peptide and is an integrin inhibitor.