T0117 |
Suplatast (Tosilate)
|
94055-76-2
|
99.34%
|
|
Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.
|
T11634 |
IL-15-IN-1
|
1831830-20-6
|
99.28%
|
|
IL-15-IN-1 is a selective and potent Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells (IC50: 0.8 μM).
|
T1846 |
Y-320
|
288250-47-5
|
99.23%
|
|
Y-320 is a new phenylpyrazoleanilide immunomodulator.
|
T5359 |
RCGD423
|
108237-91-8
|
99.14%
|
|
RCGD423, a small molecule gp130 modulator, prevents articular cartilage degeneration and promotes repair.
|
T7649 |
Tyrphostin A1
|
2826-26-8
|
99.13%
|
|
Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .
|
T6S1597 |
Mulberroside A
|
102841-42-9
|
99.05%
|
|
1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosy...
|
T14778 |
BRD6989
|
642008-81-9
|
98.82%
|
|
BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant C...
|
T4602 |
Hydrocortisone hemisuccinate
|
2203-97-6
|
98.7%
|
|
Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) is a corticosteroid used as an analytical and chromatography reagent.
|
TN1291 |
7,3',4'-Tri-O-methylluteolin
|
29080-58-8
|
98.66%
|
|
7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) has anti-inflammatory, antibacterial and antifungal activities, it also shows moderate antitry...
|
T14687 |
Deucravacitinib
|
1609392-27-9
|
98.52%
|
|
Deucravacitinib (BMS-986165) inhibits IL-12/23 and type I IFN pathways[1][2]. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for...
|
T1273 |
Diacerein
|
13739-02-1
|
98.14%
|
|
Diacerein (Fisiodar) is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diace...
|
T5641 |
RP-54745
|
135330-08-4
|
98%
|
|
RP-54745, a potential antirheumatic compound. Inhibitor of macrophage stimulation and interleukin-1 production.
|
T6761 |
Ossirene
|
106566-58-9
|
98%
|
|
Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.
|
T3571 |
SU5201
|
114727-43-4
|
97.85%
|
|
SU5201 (NSC 247030) is a biochemical.
|
T8867 |
RO2959 Hydrochloride
|
1219927-22-6
|
97.42%
|
|
RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.
|
T6S2140 |
β-Anhydroicaritin
|
38226-86-7
|
96.95%
|
|
1. β-Anhydroicaritin exhibits immunosuppressive effect on the mouse macrophages stimulated by LPS. 2. β-Anhydroicaritin phytosomes can inhibit enhanced bone turn...
|
T38105 |
Ixekizumab
|
1143503-69-8
|
95.00%
|
|
Ixekizumab (LY2439821) is a humanized IgG4 monoclonal antibody that selectively binds and neutralizes interleukin IL-17A with a Kd value of <3 pM.Ixekizumab bloc...
|
T0054 |
Disulfiram
|
97-77-8
|
95%
|
|
Disulfiram (TETD) is an inhibitor of the acetaldehyde dehydrogenase ALDH, inhibiting hALDH1 and hALDH2 (IC50=0.15/1.45 μM) with specificity. Disulfiram is acutel...
|
T13375 |
YQ128
|
2454246-18-3
|
|
|
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
|
T9913 |
Ustekinumab
|
815610-63-0
|
|
|
Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.
|