Home Tools
Log in
Cart

Interleukin

Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes) as well as some other body cells. The human genome encodes more than 50 interleukins and related proteins. The function of the immune system primarily depends on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by CD4 helper T-lymphocyte, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T0117 Suplatast (Tosilate) 94055-76-2 99.34%
Suplatast (Tosilate)
Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.
T11634 IL-15-IN-1 1831830-20-6 99.28%
IL-15-IN-1
IL-15-IN-1 is a selective and potent Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells (IC50: 0.8 μM).
T1846 Y-320 288250-47-5 99.23%
Y-320
Y-320 is a new phenylpyrazoleanilide immunomodulator.
T5359 RCGD423 108237-91-8 99.14%
RCGD423
RCGD423, a small molecule gp130 modulator, prevents articular cartilage degeneration and promotes repair.
T7649 Tyrphostin A1 2826-26-8 99.13%
Tyrphostin A1
Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .
T6S1597 Mulberroside A 102841-42-9 99.05%
Mulberroside A
1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosy...
T14778 BRD6989 642008-81-9 98.82%
BRD6989
BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant C...
T4602 Hydrocortisone hemisuccinate 2203-97-6 98.7%
Hydrocortisone hemisuccinate
Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) is a corticosteroid used as an analytical and chromatography reagent.
TN1291 7,3',4'-Tri-O-methylluteolin 29080-58-8 98.66%
7,3',4'-Tri-O-methylluteolin
7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) has anti-inflammatory, antibacterial and antifungal activities, it also shows moderate antitry...
T14687 Deucravacitinib 1609392-27-9 98.52%
Deucravacitinib
Deucravacitinib (BMS-986165) inhibits IL-12/23 and type I IFN pathways[1][2]. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for...
T1273 Diacerein 13739-02-1 98.14%
Diacerein
Diacerein (Fisiodar) is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diace...
T5641 RP-54745 135330-08-4 98%
RP-54745
RP-54745, a potential antirheumatic compound. Inhibitor of macrophage stimulation and interleukin-1 production.
T6761 Ossirene 106566-58-9 98%
Ossirene
Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.
T3571 SU5201 114727-43-4 97.85%
SU5201
SU5201 (NSC 247030) is a biochemical.
T8867 RO2959 Hydrochloride 1219927-22-6 97.42%
RO2959 Hydrochloride
RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.
T6S2140 β-Anhydroicaritin 38226-86-7 96.95%
β-Anhydroicaritin
1. β-Anhydroicaritin exhibits immunosuppressive effect on the mouse macrophages stimulated by LPS. 2. β-Anhydroicaritin phytosomes can inhibit enhanced bone turn...
T38105 Ixekizumab 1143503-69-8 95.00%
Ixekizumab
Ixekizumab (LY2439821) is a humanized IgG4 monoclonal antibody that selectively binds and neutralizes interleukin IL-17A with a Kd value of <3 pM.Ixekizumab bloc...
T0054 Disulfiram 97-77-8 95%
Disulfiram
Disulfiram (TETD) is an inhibitor of the acetaldehyde dehydrogenase ALDH, inhibiting hALDH1 and hALDH2 (IC50=0.15/1.45 μM) with specificity. Disulfiram is acutel...
T13375 YQ128 2454246-18-3
YQ128
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
T9913 Ustekinumab 815610-63-0
Ustekinumab
Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.
Suplatast (Tosilate)
T0117
Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.
IL-15-IN-1
T11634
IL-15-IN-1 is a selective and potent Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells (IC50: 0.8 μM).
Y-320
T1846
Y-320 is a new phenylpyrazoleanilide immunomodulator.
RCGD423
T5359
RCGD423, a small molecule gp130 modulator, prevents articular cartilage degeneration and promotes repair.
Tyrphostin A1
T7649
Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .
Mulberroside A
T6S1597
1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosy...
BRD6989
T14778
BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant C...
Hydrocortisone hemisuccinate
T4602
Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) is a corticosteroid used as an analytical and chromatography reagent.
7,3',4'-Tri-O-methylluteolin
TN1291
7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) has anti-inflammatory, antibacterial and antifungal activities, it also shows moderate antitry...
Deucravacitinib
T14687
Deucravacitinib (BMS-986165) inhibits IL-12/23 and type I IFN pathways[1][2]. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for...
Diacerein
T1273
Diacerein (Fisiodar) is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diace...
RP-54745
T5641
RP-54745, a potential antirheumatic compound. Inhibitor of macrophage stimulation and interleukin-1 production.
Ossirene
T6761
Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.
SU5201
T3571
SU5201 (NSC 247030) is a biochemical.
RO2959 Hydrochloride
T8867
RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.
β-Anhydroicaritin
T6S2140
1. β-Anhydroicaritin exhibits immunosuppressive effect on the mouse macrophages stimulated by LPS. 2. β-Anhydroicaritin phytosomes can inhibit enhanced bone turn...
Ixekizumab
T38105
Ixekizumab (LY2439821) is a humanized IgG4 monoclonal antibody that selectively binds and neutralizes interleukin IL-17A with a Kd value of <3 pM.Ixekizumab bloc...
Disulfiram
T0054
Disulfiram (TETD) is an inhibitor of the acetaldehyde dehydrogenase ALDH, inhibiting hALDH1 and hALDH2 (IC50=0.15/1.45 μM) with specificity. Disulfiram is acutel...
YQ128
T13375
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
Ustekinumab
T9913
Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.
1 2 3
TargetMol