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Interleukin

Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes) as well as some other body cells. The human genome encodes more than 50 interleukins and related proteins. The function of the immune system primarily depends on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by CD4 helper T-lymphocyte, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T2893 Muscone 541-91-3
Muscone
Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.
T8033 Sodium Thiocyanate 540-72-7
Sodium Thiocyanate
Sodium Thiocyanate, one of the main sources of the thiocyanate anion, is used as a precursor for the synthesis of pharmaceuticals and other specialty chemicals.
T2061 APY0201 1232221-74-7 98%
APY0201
APY0201 is a effective, highly specific, ATP-competitive PIKfyve inhibitor (IC50: 5.2 nM). It can interrupt the conversion of phosphatidylinositol 3-phosphate (P...
TN4379 Kansuinine A 57701-86-7 98%
Kansuinine A
Kansuinine A possesses analgesic props, it also shows NGF inducing activity.
T73698 Basiliximab 179045-86-4 98%
Basiliximab
Basiliximab (CHI 621) is a chimeric mouse/human IgG1 monoclonal recombinant antibody against the interleukin-2 receptor. Basiliximab has good immunosuppressive a...
T76724 Nemolizumab 1476039-58-3 98%
Nemolizumab
Nemolizumab (CIM331) is a humanized monoclonal antibody against human interleukin-31 receptor A that inhibits the binding and subsequent signal transduction of i...
T76747 Fletikumab 1357158-22-5 98%
Fletikumab
Fletikumab (NNC0109-0012) is a monoclonal antibody against IL-20 that is often used as an IL-20 inhibitor.Fletikumab is used in the study of rheumatoid arthritis...
T76775 Fezakinumab 1007106-86-6 98%
Fezakinumab
Fezakinumab is a potent monoclonal antibody to interleukin-22 (IL-22). Fezakinumab can be used to study immune system diseases and inflammation-related condition...
T76883 Talacotuzumab 1826831-79-1 98%
Talacotuzumab
Talacotuzumab (JNJ 56022473) is an IgG1 fully humanized CD123 neutralizing monoclonal antibody containing a modified Fc structure. Talacotuzumab has a high affin...
T76891 Oxelumab 1186098-83-8 98%
Oxelumab
Oxelumab (R 4930) is a human monoclonal antibody for OX40L. Oxelumab could be used to study asthma.
T76910 Astegolimab 2173054-79-8 98%
Astegolimab
Astegolimab (RG 6149) is a humanised IgG2 monoclonal antibody that targets the IL-33 receptor and inhibits IL-33 signalling. Astegolimab is used in the study of ...
T76956 Vixarelimab 2243320-83-2 98%
Vixarelimab
Vixarelimab (KPL-716) is a human anti-oncostatin M (OSM) monoclonal antibody with affinity for the beta chain of the OSM receptor and inhibition of IL-31 and OSM...
T10497 Benralizumab 1044511-01-4 98%
Benralizumab
Benralizumab (MEDI-563) is a monoclonal antibody targeting the interleukin-5 receptor alpha (IL-5Rα). It enhances antibody-dependent cell-mediated cytotoxicity, ...
T1813 VGX-1027 6501-72-0 98%
VGX-1027
VGX-1027 (GIT 27) is an isoxazole compound with various immunomodulatory properties.
T36526 IL-17 modulator 4 2446803-65-0 98%
IL-17 modulator 4
IL-17 modulator 4 is a prodrug of IL-17 modulator 1 which is an efficacious modulator of IL-17.
T26326 VU0285655-1 1158347-73-9 98%
VU0285655-1
VU0285655-1(BML-280) is a potent and selective phospholipase D2 (PLD2) inhibitor that inhibits the proliferation of PLD2-deficient cells.VU0285655-1 has an inhib...
T4403 AX-024 hydrochloride 1704801-24-0 98%
AX-024 hydrochloride
AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TN...
T0304 Methylthiouracil 56-04-2 98%
Methylthiouracil
Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.
T6207 SC144 895158-95-9 98%
SC144
SC144 is an orally active small-molecule gp130 inhibitor.
Muscone
T2893
Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.
Sodium Thiocyanate
T8033
Sodium Thiocyanate, one of the main sources of the thiocyanate anion, is used as a precursor for the synthesis of pharmaceuticals and other specialty chemicals.
APY0201
T2061
APY0201 is a effective, highly specific, ATP-competitive PIKfyve inhibitor (IC50: 5.2 nM). It can interrupt the conversion of phosphatidylinositol 3-phosphate (P...
Kansuinine A
TN4379
Kansuinine A possesses analgesic props, it also shows NGF inducing activity.
Basiliximab
T73698
Basiliximab (CHI 621) is a chimeric mouse/human IgG1 monoclonal recombinant antibody against the interleukin-2 receptor. Basiliximab has good immunosuppressive a...
Nemolizumab
T76724
Nemolizumab (CIM331) is a humanized monoclonal antibody against human interleukin-31 receptor A that inhibits the binding and subsequent signal transduction of i...
Fletikumab
T76747
Fletikumab (NNC0109-0012) is a monoclonal antibody against IL-20 that is often used as an IL-20 inhibitor.Fletikumab is used in the study of rheumatoid arthritis...
Fezakinumab
T76775
Fezakinumab is a potent monoclonal antibody to interleukin-22 (IL-22). Fezakinumab can be used to study immune system diseases and inflammation-related condition...
Talacotuzumab
T76883
Talacotuzumab (JNJ 56022473) is an IgG1 fully humanized CD123 neutralizing monoclonal antibody containing a modified Fc structure. Talacotuzumab has a high affin...
Oxelumab
T76891
Oxelumab (R 4930) is a human monoclonal antibody for OX40L. Oxelumab could be used to study asthma.
Astegolimab
T76910
Astegolimab (RG 6149) is a humanised IgG2 monoclonal antibody that targets the IL-33 receptor and inhibits IL-33 signalling. Astegolimab is used in the study of ...
Vixarelimab
T76956
Vixarelimab (KPL-716) is a human anti-oncostatin M (OSM) monoclonal antibody with affinity for the beta chain of the OSM receptor and inhibition of IL-31 and OSM...
Benralizumab
T10497
Benralizumab (MEDI-563) is a monoclonal antibody targeting the interleukin-5 receptor alpha (IL-5Rα). It enhances antibody-dependent cell-mediated cytotoxicity, ...
VGX-1027
T1813
VGX-1027 (GIT 27) is an isoxazole compound with various immunomodulatory properties.
IL-17 modulator 4
T36526
IL-17 modulator 4 is a prodrug of IL-17 modulator 1 which is an efficacious modulator of IL-17.
VU0285655-1
T26326
VU0285655-1(BML-280) is a potent and selective phospholipase D2 (PLD2) inhibitor that inhibits the proliferation of PLD2-deficient cells.VU0285655-1 has an inhib...
AX-024 hydrochloride
T4403
AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TN...
Methylthiouracil
T0304
Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.
SC144
T6207
SC144 is an orally active small-molecule gp130 inhibitor.
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TargetMol