T27026 |
CJ-13,610
|
179420-17-8
|
99.64%
|
|
CJ-13,610 is an orally active and nonredox-type inhibitor of 5-lipoxygenase (5-LOX). CJ-13,610 inhibits the biosynthesis of leukotriene B4 and regulates the expr...
|
T10719 |
CCT365623 hydrochloride
|
2126136-98-7
|
98%
|
|
CCT365623 hydrochloride is an orally active inhibitor of lysyl oxidase (LOX) (IC50: 0.89 μM). It suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF.
|
TN2688 |
2,3,4'-Trihydroxy-3',5'-dimethoxypropiophenone
|
33900-74-2
|
98%
|
|
2,3,4'-Trihydroxy-3',5'-dimethoxypropiophenone is a natural product obtained from Parinari hypochrysea (Chrysobalanaceae). 2,3,4'-Trihydroxy-3',5'-dimethoxypropi...
|
T78820 |
5-LOX-IN-5
|
|
98%
|
|
Compound 29, also known as 5-LOX-IN-5, is a 5-lipoxygenase (5-LOX) inhibitor with an inhibitory concentration 50 (IC50) of 56 nM, utilized in research pertaining...
|
T79158 |
H15-LOX-2 inhibitor 1
|
478040-08-3
|
98%
|
|
Compound 105 (h15-LOX-2 inhibitor 1) is a potent inhibitor of human epithelial 15-lipoxygenase-2 (h15-LOX-2), exhibiting an IC50 of 0.34 μM [1].
|
T79360 |
COX-2/15-LOX-IN-2
|
|
98%
|
|
COX-2/15-LOX-IN-2 is a potent inhibitor of both COX-2 and 15-LOX, demonstrating IC50 values of 0.065 μM for COX-2 and 1.86 μM for 15-LOX. Additionally, it exhibi...
|
T79361 |
COX-2/15-LOX-IN-3
|
|
98%
|
|
COX-2/15-LOX-IN-3 (compound 5k) serves as a dual inhibitor for COX-2 and 15-LOX, demonstrating inhibitory concentrations (IC50) of 0.075 μM and 1.97 μM, respecti...
|
T79362 |
COX-2/15-LOX-IN-4
|
|
98%
|
|
COX-2/15-LOX-IN-4 (compound 5i) is a dual inhibitor with IC50 values of 0.075 μM for COX-2 and 1.97 μM for 15-LOX. It inhibits LPS-induced production of pro-infl...
|
T80651 |
(-)-Bornyl ferulate
|
55511-07-4
|
98%
|
|
(-)-Bornyl ferulate is a dual inhibitor of 5-lipoxygenase and cyclooxygenase (COX), exhibiting half-maximal inhibitory concentrations (IC50s) of 10.4 μM for 5-li...
|
T10151 |
5-Lipoxygenase-In-1
|
125235-15-6
|
98%
|
|
5-Lipoxygenase-In-1 (compound example 4.10) is a 5-Lipoxygenase inhibitor.
|
T11196 |
Enazadrem
|
107361-33-1
|
98%
|
|
Enazadrem is a 5-lipoxygenase inhibitor with antiinflammatory activities.
|
TN1871 |
Ligustroside
|
35897-92-8
|
98%
|
|
Ligustroside shows little antioxidant, and anti-inflammatory properties, it shows a significant inhibition effect on prostaglandin E2 (PGE2)-release. Ligustrosid...
|
TN5174 |
Trichosanatine
|
169626-16-8
|
98%
|
|
Trichosanatine and squamosamide, as potential candidates as lead compounds for further study in drug development process with the PP2A- α protein. Trichosanatine...
|
TL0014 |
Pinusolide
|
31685-80-0
|
98%
|
|
Pinusolide is a platelet activating factor ( PAF) antagonist, it may prove of therapeutic value in the treatment of hypotension, it has antileukemic potential, a...
|
T10438 |
AZD 4407
|
166882-70-8
|
98%
|
|
AZD 4407 is a potent inhibitor of 5-lipoxygenase.
|
TN4783 |
Picralinal
|
20045-06-1
|
98%
|
|
Picralinal has anti-inflammatory and analgesic effects.
|
T4571 |
Balsalazide
|
80573-04-2
|
98%
|
|
Balsalazide (Balsalazido) is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.
|
TN5020 |
(+/-)-Sigmoidin A
|
176046-04-1
|
98%
|
|
Sigmoidin A has moderate antioxidant, antimicrobial and anti-inflammatory activity.
|
T67870 |
DKI5
|
1101130-96-4
|
98%
|
|
DKI5 ((E)-N'-benzylidenehydrazinecarbothiohydrazide) is a LOX-1 inhibitor with an IC50 value of 22.5 μM.DKI5 may have anti-inflammatory and antioxidant activitie...
|
TN4331 |
Isotachioside
|
31427-08-4
|
98%
|
|
Isotachioside has15-lipoxygenase (15-LO) inhibitory activities.
|