T1401 |
Meclofenoxate hydrochloride
|
3685-84-5
|
99.04%
|
|
Meclofenoxate hydrochloride (Lucidril) is an ester of DIMETHYLAMINOETHANOL and para-chlorophenoxyacetic acid. It has been shown to improve memory and general cog...
|
T7724 |
Tepoxalin
|
103475-41-8
|
99.03%
|
|
Tepoxalin (RWJ 20485) is a 5-lipoxygenase inhibitor potentially for the treatment of asthma, osteoarthritis. Tepoxalin inhibits COX-1, COX-2, and 5-LOX. Tepoxali...
|
T27244 |
Efletirizine
|
150756-35-7
|
98.98%
|
|
Efletirizine (UCB-28754) is a histamine receptor antagonist with inhibitory effects on the enzyme 5-lipoxygenase (5-LO), and is useful in the topical treatment o...
|
T12784 |
RWJ 63556
|
190967-35-2
|
98.91%
|
|
RWJ 63556 is an orally active inhibitor of COX-2 selective/5-lipoxygenase, shows anti-inflammatory activities.
|
T6S0413 |
Pectolinarigenin
|
520-12-7
|
98.77%
|
|
1. Pectolinarigenin (Pectolinaringenin) exhibits hepatoprotective activity mainly via SOD antioxidant mechanism. 2. Pectolinarigenin possesses anti-inflammatory ...
|
T8794 |
4-MMPB
|
928853-86-5
|
98.75%
|
|
15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM. 4-MMPB (15-Lipoxygenase Inhibitor 1) has IC50s of 19.5 μM and 19....
|
T16817 |
S-2474
|
158089-95-3
|
98.72%
|
|
S-2474, an inhibitor of COX-2 and 5-lipoxygenase, has anti-inflammatory and neuroprotective activities and inhibits Abeta (25 - 35) and Abeta (1 - 40) induced ce...
|
TN1097 |
β-Boswellic acid
|
631-69-6
|
98.31%
|
|
β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemic acti...
|
TN1255 |
3-O-Acetyl-11-hydroxy-beta-boswellic acid
|
146019-25-2
|
98.24%
|
|
3-O-Acetyl-11-hydroxy-beta-boswellic acid is the precursor of 3-O-acetyl-9, 11-dehydro-beta-boswellic acid(a 5-lipoxygenase inhibitor ).
|
T8950 |
CAY10698
|
684236-01-9
|
98.23%
|
|
CAY10698 is a 12-lipoxygenase inhibitor (12-LO; IC50 of 5.1 µM).
|
T65427 |
5-LOX inhibitor
|
106461-41-0
|
98.01%
|
|
5-LOX inhibitor (1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one) is one of the impurities of itraconazole, a selective ...
|
T5759 |
S-(+)-Marmesin
|
13849-08-6
|
98.00%
|
|
S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.
|
T5714 |
5-O-Demethylnobiletin
|
2174-59-6
|
98%
|
|
5-O-Demethylnobiletin (5-DEMETHYLNOBILETIN) is a natual product, has anti-inflammatory activity, it may act through a direct inhibition of 5-LOX, without affecti...
|
T7540 |
2,5-Di-tert-butylhydroquinone
|
88-58-4
|
98%
|
|
2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.
|
T6243 |
U-73122
|
112648-68-7
|
97.98%
|
|
U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.
|
T0646 |
5-Aminosalicylic Acid
|
89-57-6
|
97.88%
|
|
5-Aminosalicylic Acid (5-ASA) is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is consid...
|
T21902 |
ML351
|
847163-28-4
|
97.86%
|
|
ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).
|
TN1016 |
Kukoamine A
|
75288-96-9
|
97.45%
|
|
Kukoamine A possesses anticancer, cytoprotective, antioxidant, and anti-inflammatory activities, it also has neuroprotective effects through inhibiting oxidative...
|
T61211 |
5-LOX-IN-1
|
55040-82-9
|
97.45%
|
|
5-LOX-IN-1 is a 5-Lipoxygenase (5-LOX) inhibitor (IC50: 2.3 μM).5-LOX-IN-1 can be used for cancer research.
|
T77288 |
KKII5
|
6381-55-1
|
97.44%
|
|
KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of s...
|