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MMP

Matrix metallopeptidases (MMPs), also known as matrix metalloproteinases or matrixins, are metalloproteinases that are calcium-dependent zinc-containing endopeptidases; other family members are adamalysins, serralysins, and astacins. The MMPs belong to a larger family of proteases known as the metzincin superfamily.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
TN1376 α-Solanine 20562-02-1 98%
α-Solanine
Alpha-Solanine alters antioxidative enzyme activities and MDA and PCO concentrations and GST activity in fat body and midgut.
TN3691 Communic acid 2761-77-5 98%
Communic acid
Communic acid has antibacterial activity, including against mycobacterial. trans-Communic acid has potential to be utilized as anti-wrinkling agents and cosmetic...
T69685 AGPS-IN-2i 2316782-88-2 98%
AGPS-IN-2i
AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces eth...
T13358 XL-784 1224964-36-6 98%
XL-784
XL-784 is a selective inhibitor of matrix metalloproteinases (MMP)(IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1,MMP-2,MMP-3,MMP-8,MMP-9,MMP-13,respecti...
T6009 TAPI1 163847-77-6 98%
TAPI1
TAPI1 (TAPI) , an ADAM17/TACE inhibitor, inhibits shedding of cytokine receptors.
T37048L MMP-3 Inhibitor acetate 98%
MMP-3 Inhibitor acetate
MMP-3 Inhibitor acetate is a cell-permeable and potent inhibitor of human MMP-3.
TN4437 Licorisoflavan A 129314-37-0 98%
Licorisoflavan A
Licorisoflavan A shows weak scavenging activity against superoxide anion radical, it and licoricidin have potential for the development of novel host-modulating ...
T12539 Prinomastat hydrochloride 1435779-45-5 98%
Prinomastat hydrochloride
Prinomastat hydrochloride is a orally active inhibitor of metalloproteinase (MMP)(MMP-1, MMP-3 and MMP-9 with IC50s of 79, 6.3 and 5.0 nM , respectively),with An...
TN5174 Trichosanatine 169626-16-8 98%
Trichosanatine
Trichosanatine and squamosamide, as potential candidates as lead compounds for further study in drug development process with the PP2A- α protein. Trichosanatine...
TN3616 Cedrelone 1254-85-9 98%
Cedrelone
Cedrelone is a citrulline analog and a phenazine biosynthesis-like domain protein (PBLD) activator.Cedrelone induces apoptosis in cancer cells.Cedrelone is a ver...
T12762 Ro 31-9790 145337-55-9 98%
Ro 31-9790
Ro 31-9790 is a synthetic inhibitor of metalloproteinase (MMP).
T74632 TP0556351 2787582-17-4 98%
TP0556351
TP0556351, a potent and selective inhibitor of matrix metalloproteinase-2 (MMP2), exhibits significant efficacy with an IC50 of 0.2 nM and demonstrates the capab...
TN1615 Epitheaflagallin 3-O-gallate 102067-92-5 98%
Epitheaflagallin 3-O-gallate
Epitheaflagallin 3-O-gallate is a promising functional food material with potential antiobesity and antiperiodontal disease activities, it suppresses tumor growt...
TQ0129 TNF Protease Inhibitor 2 187034-31-7 98%
TNF Protease Inhibitor 2
TAPI-2 is a broad-spectrum inhibitor of MMP (IC50: 20 μM), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM).
TN2697 2,3-Dihydrohinokiflavone 34292-87-0 98%
2,3-Dihydrohinokiflavone
2,3-Dihydrohinokiflavone is a suppressor of matrix metalloproteinases (MMP) gene expression and shows strong activity against Leishmania with an IC50 of 1.6 μM.
TN1093 Ginsenoside F4 181225-33-2 98%
Ginsenoside F4
Ginsenoside F4 has inhibitory effect on human lymphocytoma JK cell by inducing its apoptosis, the mechanism is related to the mitochondrial dysfunction and the i...
TN2775 2-Methoxystypandrone 85122-21-0 98%
2-Methoxystypandrone
2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflamm...
T12511 PNU-248686A 341498-89-3 98%
PNU-248686A
PNU-248686A is an inhibitor of matrix metalloproteinase (MMP).
TN2075 Pimaric acid 127-27-5 98%
Pimaric acid
Pimaric acid has potent anti-atherosclerotic activity with inhibitory action on matrix metalloproteinase-9 production and cell migration in TNF-α±-induced human ...
T12082 MMP3 inhibitor 1 312930-75-9 98%
MMP3 inhibitor 1
MMP3 inhibitor 1 is a potent and highly selective inhibitor of MMP-3 (IC50 of 1 nM).
α-Solanine
TN1376
Alpha-Solanine alters antioxidative enzyme activities and MDA and PCO concentrations and GST activity in fat body and midgut.
Communic acid
TN3691
Communic acid has antibacterial activity, including against mycobacterial. trans-Communic acid has potential to be utilized as anti-wrinkling agents and cosmetic...
AGPS-IN-2i
T69685
AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces eth...
XL-784
T13358
XL-784 is a selective inhibitor of matrix metalloproteinases (MMP)(IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1,MMP-2,MMP-3,MMP-8,MMP-9,MMP-13,respecti...
TAPI1
T6009
TAPI1 (TAPI) , an ADAM17/TACE inhibitor, inhibits shedding of cytokine receptors.
MMP-3 Inhibitor acetate
T37048L
MMP-3 Inhibitor acetate is a cell-permeable and potent inhibitor of human MMP-3.
Licorisoflavan A
TN4437
Licorisoflavan A shows weak scavenging activity against superoxide anion radical, it and licoricidin have potential for the development of novel host-modulating ...
Prinomastat hydrochloride
T12539
Prinomastat hydrochloride is a orally active inhibitor of metalloproteinase (MMP)(MMP-1, MMP-3 and MMP-9 with IC50s of 79, 6.3 and 5.0 nM , respectively),with An...
Trichosanatine
TN5174
Trichosanatine and squamosamide, as potential candidates as lead compounds for further study in drug development process with the PP2A- α protein. Trichosanatine...
Cedrelone
TN3616
Cedrelone is a citrulline analog and a phenazine biosynthesis-like domain protein (PBLD) activator.Cedrelone induces apoptosis in cancer cells.Cedrelone is a ver...
Ro 31-9790
T12762
Ro 31-9790 is a synthetic inhibitor of metalloproteinase (MMP).
TP0556351
T74632
TP0556351, a potent and selective inhibitor of matrix metalloproteinase-2 (MMP2), exhibits significant efficacy with an IC50 of 0.2 nM and demonstrates the capab...
Epitheaflagallin 3-O-gallate
TN1615
Epitheaflagallin 3-O-gallate is a promising functional food material with potential antiobesity and antiperiodontal disease activities, it suppresses tumor growt...
TNF Protease Inhibitor 2
TQ0129
TAPI-2 is a broad-spectrum inhibitor of MMP (IC50: 20 μM), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM).
2,3-Dihydrohinokiflavone
TN2697
2,3-Dihydrohinokiflavone is a suppressor of matrix metalloproteinases (MMP) gene expression and shows strong activity against Leishmania with an IC50 of 1.6 μM.
Ginsenoside F4
TN1093
Ginsenoside F4 has inhibitory effect on human lymphocytoma JK cell by inducing its apoptosis, the mechanism is related to the mitochondrial dysfunction and the i...
2-Methoxystypandrone
TN2775
2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflamm...
PNU-248686A
T12511
PNU-248686A is an inhibitor of matrix metalloproteinase (MMP).
Pimaric acid
TN2075
Pimaric acid has potent anti-atherosclerotic activity with inhibitory action on matrix metalloproteinase-9 production and cell migration in TNF-α±-induced human ...
MMP3 inhibitor 1
T12082
MMP3 inhibitor 1 is a potent and highly selective inhibitor of MMP-3 (IC50 of 1 nM).
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TargetMol