T12539L |
Prinomastat
|
192329-42-3
|
98%
|
|
Prinomastat inhibits MMP-2, MMP-3 and MMP-9 (Kis: 0.05 nM, 0.3 nM and 0.26 nM, respectively). Prinomastat crosses the blood-brain barrier. It also has antitumor ...
|
T17201 |
UK 356618
|
230961-08-7
|
98%
|
|
UK 356618 is a potent and selective inhibitor of matrix metalloprotease-3 (IC50: 5.9 nM).
|
TN4978 |
Scutellarein-7-O-glucoside
|
26046-94-6
|
98%
|
|
Scutellarein-7-O-glucoside inhibites MMP-2 activity.
|
TN1998 |
Notoginsenoside T5
|
769932-34-5
|
98%
|
|
Total panax notoginsenosides (TPNS) are the main active ingredients in San-Chi, the root of(Burk) F.H. Chen, which belongs to the Araliaceae family and has been ...
|
T16137 |
MRS1177
|
183721-13-3
|
98%
|
|
MRS1177 is an effective and selective antagonist of the human Adenosine A3 receptor (hA3AR) (Ki: 0.3 nM).
|
T13249 |
UK-370106
|
230961-21-4
|
98%
|
|
UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-fibronecti...
|
T28985 |
TMI-1
|
287403-39-8
|
98%
|
|
TMI-1 (WAY-171318), a novel orally active inhibitor of ADAM17 (TACE) and MMP, induces tumor apoptosis in a breast cancer.
|
T10461 |
Batimastat sodium salt
|
130464-84-5
|
98%
|
|
Batimastat (BB-94) sodium salt is a broad-spectrum MMP inhibitor (IC50s: 3, 4, 4, 6, and 20 nM for MMP-1, MMP-2, MMP-9, MMP-7, and MMP-3).
|
TN4046 |
Excisanin A
|
78536-37-5
|
98%
|
|
ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a pote...
|
T14312 |
Apratastat
|
287405-51-0
|
98%
|
|
Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs) an...
|
T16986 |
Tanomastat
|
179545-77-8
|
98%
|
|
Tanomastat is an orally bioavailable and non-peptidic biphenyl matrix metalloproteinases inhibitor. For MMP-2, MMP-3, MMP-9, MMP-13 the Ki values are 11, 143, 30...
|
TN5153 |
Torilin
|
13018-10-5
|
98%
|
|
Torilin is an inhibitor of testosterone 5 alpha-reductase, it (IC50 = 31.7 +/- 4.23 microM) shows a stronger inhibition of 5 alpha-reductase than alpha-linolenic...
|
T1402 |
Fenofibric acid
|
42017-89-0
|
99.94%
|
|
Fenofibric acid (FNF acid) is the active form of fenofibrate, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity.
|
T1592 |
Acetohydroxamic acid
|
546-88-3
|
99.91%
|
|
Acetohydroxamic acid (N-Hydroxyacetamide) is an antagonist of the bacterial enzyme urease.
|
T4082 |
Astragaloside
|
17429-69-5
|
99.9%
|
|
Astragaloside, one of the main active ingredients in Astragalus membranaceus.
|
T1687 |
Doxycycline
|
564-25-0
|
99.88%
|
|
Doxycycline (Doxiciclina) belongs to the tetracycline class of antibiotics and is a broad-spectrum metalloproteinase (MMP) inhibitor with oral activity. Doxycycl...
|
T7044 |
Norepinephrine
|
51-41-2
|
99.84%
|
|
Norepinephrine (Levophed) can stimulate apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway. It can up-regulate the expression ...
|
T3414 |
Morroniside
|
25406-64-8
|
99.84%
|
|
Morroniside would act as a regulator of hepatic inflammatory reactions and lipid metabolism in db/db mice. It exhibits protective effects against diabetic renal ...
|
T2993 |
Cordycepin
|
73-03-0
|
99.78%
|
|
Cordycepin (3'-Deoxyadenosine) is a purine nucleoside antimetabolite and antibiotic isolated from the fungus Cordyceps militaris with potential antineoplastic ac...
|
T77617 |
MMP-9-IN-6
|
2241964-36-1
|
99.75%
|
|
MMP-9-IN-6 is an MMP-9 inhibitor with an IC50 value of 50 μM and good anti-ulcer efficacy.MMP-9-IN-6 has potential anti-tumor activity and can be used to study t...
|