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Cat No. | Product Name | Synonyms | Targets |
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T14301 | Apararenone | MT-3995 | Glucocorticoid Receptor |
Apararenone (MT-3995) is a receptor antagonist of mineralocorticoid receptor which can be used to treat non-alcoholic steatohepatitis and diabetic nephropathy. | |||
T10305 | Amiselimod hydrochloride | MT-1303 hydrochloride | S1P Receptor , LPL Receptor |
Amiselimod hydrochloride (MT-1303 hydrochloride) is a sphingosine 1-phosphate receptor-1 (S1P1) modulator. | |||
T15034 | Roluperidone | CYR-101,MIN-101,MT-210 | Sigma receptor , 5-HT Receptor |
Roluperidone (CYR-101) is a novel cyclic amide derivative. It has high equipotent affinities for 5-HT2A and σ2 receptors (Ki of 7.53 nM and 8.19 nM for 5-HT2A and σ2). | |||
T6973 | RS-127445 | MT500 | 5-HT Receptor |
RS-127445 (MT500) is a selective 5-HT2B receptor antagonist with pKi of 9.5 and pIC50 of 10.4, exhibits >1000-fold selectivity against other 5-HT receptors. | |||
T7519 | RS-127445 hydrochloride | RS 127445,MT 500 | 5-HT Receptor |
RS-127445 hydrochloride (MT 500) is a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist(pKi : 9.5). | |||
TP1097 | Melanotan I | [Nle4,D-Phe7]-α-MSH,Afamelanotide,MT-I | Others |
Melanotan I is a non-specific melanocortin receptor (MCR) agonist, an α-melanocyte-stimulating hormone (α-MSH) analog, which is injected subcutaneously to increase the amount of melanin in the skin Melanotan I is used as... | |||
T7589 | Afamelanotide acetate | afamelanotide | Melanocortin Receptor |
Afamelanotide acetate is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist, used to for Erythropoietic Protoporphyria. | |||
T1900 | LDN-212854 | LDN212854,BMP Inhibitor III | ALK , TGF-beta/Smad |
LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-β type I receptors; possesses differences towards ALK2(IC50=1.3 nM) versus ALK1/3 compared to other inhibitors. | |||
TP1324 | Melanotan (MT)-II | Melanocortin Receptor | |
Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH). | |||
T25310 | Dersimelagon | MT-7117 | Melanocortin Receptor |
Dersimelagon (MT-7117) is an orally active, selective agonist for the melanocortin 1 receptor (MC1R), demonstrating EC50 values of 8.16 nM (h), 3.91 nM (cm), 1.14 nM (m), and 0.251 nM (r) across species such as human, cy... | |||
T29044 | UCM 765 | UCM-765,UCM765 | |
UCM 765 is a partial agonist of melatonin MT(2) receptor. | |||
T60490 | Melatonin receptor agonist 1 | ||
Melatonin receptor agonist 1 (compound 20c) is a potent agonist of melatonin receptor (MT) with Ki values of 108 nM for MT2 and 1140 nM for MT 1 [1]. | |||
T1463 | Ramelteon | TAK-375 | Melatonin Receptor , MT Receptor |
Ramelteon (TAK-375) is a Melatonin Receptor Agonist. The mechanism of action of ramelteon is as a Melatonin Receptor Agonist. | |||
T71214 | MT-7716 HCl hydrate | ||
MT-7716 HCl hydrate is a NOP receptor agonist. | |||
T12120 | MT-7716 hydrochloride | W-212393 hydrochloride | Others |
MT-7716 hydrochloride is a selective agonist of non-peptide nociceptin receptor (NOP) | |||
T12120L | MT-7716 free base | W-212393 | Others |
MT-7716 free base is a selective non-peptide agonist of nociceptin receptor (NOP). It is used for promising potential treatment drugs for alcohol abuse and relapse prevention. | |||
T70035 | Tasimelteon-d5 | ||
Tasimelteon-d5 is intended for use as an internal standard for the quantification of tasimelteon by GC- or LC-MS. Tasimelteon is a melatonin (MT) receptor agonist. It selectively binds MT1 and MT2 receptors over a panel ... | |||
T69081 | KRH-1636 | ||
KRH-1636 is an orally active, selective and extremely potent CXC chemokine receptor 4 antagonist. KRH-1636 exhibits a potent and selective anti-HIV-1 activity. KRH-1636 efficiently blocked replication of various T cell ... | |||
T83769 | TC 14012 hydrochloride | H-Arg-Arg-Nal-Cys-Tyr-Cit-Lys-D-Cit-Pro-Tyr-Arg-Cit-Cys-Arg-NH2 | |
TC 14012, a peptidomimetic compound, acts as both an antagonist to the chemokine (C-X-C motif) receptor 4 (CXCR4; IC50 = 2.9 nM) and as an agonist for CXCR7, effectively recruiting β-arrestin in HEK293T cells that expres... |
Cat No. | Product Name | Species | Expression System |
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TMPY-02028 | RON/CD136 Protein, Human, Recombinant (His) | Human | HEK293 |
The tyrosine kinase receptor, macrophage-stimulating 1 receptor (MST1R), a c-met-related tyrosine kinase, also known as the Ron receptor or CD136, controls cell survival and motility programs related to invasive growth. ... |