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MTH1

T2037 TH588 TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells.
T2069 TH287 hydrochloride TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.
T6357 (S)-crizotinib (S)-crizotinib（IC50 of 72 nM），an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.
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