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Melanocortin Receptor

Melanocortin receptors are members of the rhodopsin family of 7-transmembrane G protein-coupled receptors. There are five known members of the melanocortin receptor system:MC1R,MC2R,MC3R,MC4R,MC5R.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
TP1101 Nonapeptide-1 acetate salt (158563-45-2 free base) TP1101 98.26%
Nonapeptide-1 acetate salt (158563-45-2 free base)
Nonapeptide-1 acetate salt (158563-45-2 free base) (Melanostatine-5 acetate salt) , a peptide hormone, is a potent α-Melanocyte-stimulating hormone (α-MSH) antag...
TP1952L PG 106 acetate 98.24%
PG 106 acetate
PG 106 acetate is an effective and selective antagonist of the human melanocortin 3 (hMC3) receptor with an IC50 of 210 nM. PG 106 acetate has no activity with t...
T7589 Afamelanotide acetate 1566590-77-9 98%
Afamelanotide acetate
Afamelanotide acetate is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist, used to for Erythropoietic Pro...
T7608 Bremelanotide Acetate 1607799-13-2 98%
Bremelanotide Acetate
Bremelanotide Acetate (PT-141 Acetate) is an agonist of melanocortin receptor (MCR) .
TP1578L Neuropeptide EI, rat acetate TP1578L 95.55%
Neuropeptide EI, rat acetate
Neuropeptide EI, rat acetate Displays functional MCH-antagonist and MSH-agonist activity in different behavioral paradigms.
T12882L Setmelanotide Acetate(920014-72-8 free base) 2759937-80-7 100%
Setmelanotide Acetate(920014-72-8 free base)
Setmelanotide Acetate(920014-72-8 free base) (RM-493 Acetate) is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM a...
TP1248L ACTH 11-24 acetate(4237-93-8 free base) 79190-56-0 100%
ACTH 11-24 acetate(4237-93-8 free base)
ACTH 11-24 acetate(4237-93-8 free base) (Adrenocorticotropic Hormone (11-24) acetate) is a fragment of adrenocorticotrophin, induces cortisol release. ACTH (11-2...
TP1893L1 [D-Trp8]-γ-MSH acetate(321351-81-9 free base) TP1893L1 100%
[D-Trp8]-γ-MSH acetate(321351-81-9 free base)
Selective melanocortin 3 (MC3) receptor agonist (IC50 values are 6.7, 340 and 600 nM for human MC3, MC5 and MC4 receptors respectively). Displays anti-inflammato...
TP2015L HS 014 acetate(207678-81-7 free base) TP2015L 100%
HS 014 acetate(207678-81-7 free base)
HS 014 acetate is a potent and selective melanocortin MC4 receptor antagonist (Ki values are 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 re...
TP1324 Melanotan (MT)-II 121062-08-6 100%
Melanotan (MT)-II
Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH).
T7813 α-MSH 581-05-5 100%
α-MSH
α-MSH (MSH, amide) is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.
TP1898 HS024 212370-59-7 100%
HS024
HS024 is a highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respec...
TP1011L ACTH (1-17) acetate 98%
ACTH (1-17) acetate
ACTH (1-17) acetate is a potent agonist at the human melanocortin 1 (MC1) receptor with high affinity(Ki = 0.21 nM).
T25310 Dersimelagon 1835256-48-8 98%
Dersimelagon
Dersimelagon (MT-7117) is an orally active, selective agonist for the melanocortin 1 receptor (MC1R), demonstrating EC50 values of 8.16 nM (h), 3.91 nM (cm), 1.1...
T20501 Undecylenoyl phenylalanine 175357-18-3 98%
Undecylenoyl phenylalanine
Undecylenoyl phenylalanine (Sepiwhite msh QD) is a novel depigmenting agent, which possibly acts as an alpha-melanocyte-stimulating hormone antagonist, thus inhi...
Nonapeptide-1 acetate salt (158563-45-2 free base)
TP1101
Nonapeptide-1 acetate salt (158563-45-2 free base) (Melanostatine-5 acetate salt) , a peptide hormone, is a potent α-Melanocyte-stimulating hormone (α-MSH) antag...
PG 106 acetate
TP1952L
PG 106 acetate is an effective and selective antagonist of the human melanocortin 3 (hMC3) receptor with an IC50 of 210 nM. PG 106 acetate has no activity with t...
Afamelanotide acetate
T7589
Afamelanotide acetate is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist, used to for Erythropoietic Pro...
Bremelanotide Acetate
T7608
Bremelanotide Acetate (PT-141 Acetate) is an agonist of melanocortin receptor (MCR) .
Neuropeptide EI, rat acetate
TP1578L
Neuropeptide EI, rat acetate Displays functional MCH-antagonist and MSH-agonist activity in different behavioral paradigms.
Setmelanotide Acetate(920014-72-8 free base)
T12882L
Setmelanotide Acetate(920014-72-8 free base) (RM-493 Acetate) is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM a...
ACTH 11-24 acetate(4237-93-8 free base)
TP1248L
ACTH 11-24 acetate(4237-93-8 free base) (Adrenocorticotropic Hormone (11-24) acetate) is a fragment of adrenocorticotrophin, induces cortisol release. ACTH (11-2...
[D-Trp8]-γ-MSH acetate(321351-81-9 free base)
TP1893L1
Selective melanocortin 3 (MC3) receptor agonist (IC50 values are 6.7, 340 and 600 nM for human MC3, MC5 and MC4 receptors respectively). Displays anti-inflammato...
HS 014 acetate(207678-81-7 free base)
TP2015L
HS 014 acetate is a potent and selective melanocortin MC4 receptor antagonist (Ki values are 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 re...
Melanotan (MT)-II
TP1324
Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH).
α-MSH
T7813
α-MSH (MSH, amide) is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.
HS024
TP1898
HS024 is a highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respec...
ACTH (1-17) acetate
TP1011L
ACTH (1-17) acetate is a potent agonist at the human melanocortin 1 (MC1) receptor with high affinity(Ki = 0.21 nM).
Dersimelagon
T25310
Dersimelagon (MT-7117) is an orally active, selective agonist for the melanocortin 1 receptor (MC1R), demonstrating EC50 values of 8.16 nM (h), 3.91 nM (cm), 1.1...
Undecylenoyl phenylalanine
T20501
Undecylenoyl phenylalanine (Sepiwhite msh QD) is a novel depigmenting agent, which possibly acts as an alpha-melanocyte-stimulating hormone antagonist, thus inhi...
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TargetMol