Home Tools
Log in
Cart

Search Result

Search Results for " microtubule-associated "

16

Compounds

1

Natural Products

18

Recombinant Proteins

2

Libraries

Cat No. Product Name Synonyms Targets
TP1420 Microtubule-associated protein tau (26-44)
Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.
T9504 MAP4343 Microtubule Associated
Map4343 is a 3-methyl ether derivative of pregnenolone. Map4343 binds to microtubule associated protein 2 (MAP2) in vitro and stimulates tubulin polymerization, resulting in enhanced neurite extension and protection of n...
T60688 MKI-1 MASTL Kinase Inhibitor-1 Others
MKI-1 is an inhibitor of MASTL (microtubule-associated serine/threonine kinase-like, IC50= 9.9 μM). MKI-1 exerts radiosensitizer and antitumor activities through PP2A activation in breast cancer.
T15612 JH-VIII-157-02 Microtubule Associated , ALK
JH-VIII-157-02 is an inhibitor of ALK and inhibits echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) with IC50s of 2 nM for EML4-ALK G1202R, EML4-ALKwt, EML4-ALK C1156Y, EML4-ALK F1174L, and EML4-ALK F1174L...
T11184 EML4-ALK kinase inhibitor 1 EML4 ALK kinase inhibitor 1,EML4-​ALK kinase inhibitor 1 ALK
EML4-ALK kinase inhibitor 1 (EML4 ALK kinase inhibitor 1) is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM.
T76726 Zagotenemab LY33003560 Microtubule Associated
Zagotenemab is a humanized antibody against the microtubule-associated protein tau that selectively regulates tau deposits in the brain. Zagotenemab can be used to study neurological disorders such as Alzheimer's disease...
T25043 Alestramustine
Alestramustine is a cytostatic antineoplastic agent. The drug, via its active metabolites, binds to microtubule-associated proteins and β-tubulin and interferes with microtubule function, thereby suppressing cell divisio...
T80616 Posdinemab
Posdinemab, a humanized IgG1κ antibody, targets the microtubule-associated protein tau (MAPT) [1].
T68873 Cornigerine
Cornigerine is a natural product analog of colchicine produced by Colchicum cornigerum that inhibited tubulin polymerization both with and without microtubule-associated proteins, inhibited the binding of radiolabeled co...
T81850 MASTL-IN-2
MASTL-IN-2 is a potent inhibitor of microtubule-associated serine/threonine kinase-like (MASTL). It demonstrates notable efficacy in suppressing the proliferation of human epithelial MIA PaCa cancer cells, exhibiting an ...
T81851 MASTL-IN-1
MASTL-IN-1 is a potent inhibitor of microtubule-associated serine/threonine kinase-like (MASTL), which plays a role in cell proliferation, migration, and invasion, thereby holding promise in cancer research [1].
T78552 PB118
PB118 has the capacity to effectively clear Aβ deposits by augmenting phagocytosis, enhance the tubulin/microtubule network through increased acetyl α-tubulin levels, modulate various inflammation-associated cytokines an...
T70808 Cabazitaxel-d6
Cabazitaxel-d6 is a deuterium labeled cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. Cabazitaxel binds to and stabilizes tubu...
T69305 Milataxel
Milataxel is an orally bioavailable taxane with potential antineoplastic activity. Upon oral administration, milataxel and its major active metabolite M-10 bind to and stabilize tubulin, resulting in the inhibition of mi...
T71217 MPT0B214
MPT0B214 is a novel and potent microtubule inhibitor with potential anticancer activity. MPT0B214 inhibited tubulin polymerization through strongly binding to the tubulin's colchicine-binding site and had cytotoxic activ...
T68743 AZD4877 HCl
AZD4877 is a synthetic kinesin spindle protein (KSP) inhibitor with potential antineoplastic activity. KSP inhibitor AZD4877 selectively inhibits microtubule motor protein KSP (also called kinesin-5 or Eg5), which may re...
Cat No. Product Name Synonyms Targets
T3S0209 Vincristine ERK , p38 MAPK , NF-κB , Akt , JNK , mTOR
Vincristine binds to tubulin and inhibits the formation of microtubules, thereby inhibiting mitosis of the cancer cell. Vincristine can be used as a microtubule-destabilizing agent for research on the treatment of hemato...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-03425 Tau Protein, Human, Recombinant (His) Human E. coli
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are...
TMPY-03340 MAP1LC3A Protein, Human, Recombinant (His) Human E. coli
LC3A, also known as MAP1LC3A, is one of the light chain subunits that function together with both MAP1A and/or MAP1B. MAP1A and MAP1B are microtubule-associated proteins that mediate the physical interactions between mic...
TMPY-03749 LC3B Protein, Human, Recombinant (His) Human E. coli
MAP1LC3B (Microtubule Associated Protein 1 Light Chain 3 beta, also known as LC3B) is a Protein Coding gene. The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are in...
TMPJ-00828 Tau-F Protein, Human, Recombinant Human E. coli
Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons...
TMPJ-00827 Tau-D Protein, Human, Recombinant (His) Human E. coli
Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. ...
TMPJ-01321 MAP1LC3B Protein, Human, Recombinant Human E. coli
Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B) is a member of the highly conserved ATG8 protein family. ATG8 proteins are present in all known eukaryotic organisms. MAP1LC3B is one of the four genes in t...
TMPY-03865 EB3 Protein, Human, Recombinant (His) Human E. coli
MAPRE3 (Microtubule Associated Protein RP/EB Family Member 3, also known as EB3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. MAPRE3 is a member of the RP/EB family. It localizes t...
TMPH-01139 Human coronavirus 229E Spike glycoprotein (His) HCoV-229E HEK293
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocy...
TMPJ-00016 GABARAP Protein, Human, Recombinant (GST) Human E. coli
Gamma-Aminobutyric Acid Receptor-Associated Protein (GABARAP) is a ligand-gated chloride channel protein that mediates inhibitory neurotransmission and belongs to the MAP1 LC3 family. GABARAP is highly positively charged...
TMPJ-00015 GABARAP Protein, Human, Recombinant (His & hFc) Human E. coli
Gamma-Aminobutyric Acid Receptor-Associated Protein (GABARAP) is a ligand-gated chloride channel protein that mediates inhibitory neurotransmission and belongs to the MAP1 LC3 family. GABARAP is highly positively charged...
TMPY-00994 MOG Protein, Human, Recombinant (aa 30-149, His) Human E. coli
Myelin oligodendrocyte glycoprotein (MOG) is a transmembrane protein belonging to the immunoglobulin superfamily and contains an Ig-like domain followed by two potential membrane-spanning regions. MOG is expressed only i...
TMPY-02565 MOG Protein, Mouse, Recombinant (aa 30-149, His) Mouse E. coli
Myelin oligodendrocyte glycoprotein (MOG) is a transmembrane protein belonging to the immunoglobulin superfamily and contains an Ig-like domain followed by two potential membrane-spanning regions. MOG is expressed only i...
TMPY-01715 CDC37 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
CDC37 is a protein that is expressed in proliferative zones during embryonic development and in adult tissues, consistent with a positive role in proliferation and is required for cell division in budding yeast. CDC37 is...
TMPY-03534 CDC37 Protein, Mouse, Recombinant (His & GST) Mouse Baculovirus-Insect Cells
CDC37 is a protein that is expressed in proliferative zones during embryonic development and in adult tissues, consistent with a positive role in proliferation and is required for cell division in budding yeast. CDC37 is...
TMPY-03558 CDC37 Protein, Mouse, Recombinant Mouse Baculovirus-Insect Cells
CDC37 is a protein that is expressed in proliferative zones during embryonic development and in adult tissues, consistent with a positive role in proliferation and is required for cell division in budding yeast. CDC37 is...
TMPH-02041 ARHGEF12 Protein, Human, Recombinant (His) Human E. coli
Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TC...
TMPY-02718 Doublecortin/DCX Protein, Human, Recombinant (aa 45-150, GST) Human E. coli
DCX (doublecortin, N-GST chimera)contains 2 doublecortin domains and belongs to the doublecortin family. It is highly expressed in neuronal cells of fetal brain, but not expressed in other fetal tissues. In the adult, it...
TMPH-01458 Human herpesvirus 6B (HHV-6 variant B) (strain Z29) Protein U22 (His) HHV-6B in vitro E. coli expression system
Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not have activity toward 'Lys-48'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes...
Tau Protein, Human, Recombinant (His)
TMPY-03425
Species: Human
Expression System: E. coli
MAP1LC3A Protein, Human, Recombinant (His)
TMPY-03340
Species: Human
Expression System: E. coli
LC3B Protein, Human, Recombinant (His)
TMPY-03749
Species: Human
Expression System: E. coli
Tau-F Protein, Human, Recombinant
TMPJ-00828
Species: Human
Expression System: E. coli
Tau-D Protein, Human, Recombinant (His)
TMPJ-00827
Species: Human
Expression System: E. coli
MAP1LC3B Protein, Human, Recombinant
TMPJ-01321
Species: Human
Expression System: E. coli
EB3 Protein, Human, Recombinant (His)
TMPY-03865
Species: Human
Expression System: E. coli
Human coronavirus 229E Spike glycoprotein (His)
TMPH-01139
Species: HCoV-229E
Expression System: HEK293
GABARAP Protein, Human, Recombinant (GST)
TMPJ-00016
Species: Human
Expression System: E. coli
GABARAP Protein, Human, Recombinant (His & hFc)
TMPJ-00015
Species: Human
Expression System: E. coli
MOG Protein, Human, Recombinant (aa 30-149, His)
TMPY-00994
Species: Human
Expression System: E. coli
MOG Protein, Mouse, Recombinant (aa 30-149, His)
TMPY-02565
Species: Mouse
Expression System: E. coli
CDC37 Protein, Human, Recombinant (GST)
TMPY-01715
Species: Human
Expression System: Baculovirus-Insect Cells
CDC37 Protein, Mouse, Recombinant (His & GST)
TMPY-03534
Species: Mouse
Expression System: Baculovirus-Insect Cells
CDC37 Protein, Mouse, Recombinant
TMPY-03558
Species: Mouse
Expression System: Baculovirus-Insect Cells
ARHGEF12 Protein, Human, Recombinant (His)
TMPH-02041
Species: Human
Expression System: E. coli
Doublecortin/DCX Protein, Human, Recombinant (aa 45-150, GST)
TMPY-02718
Species: Human
Expression System: E. coli
Human herpesvirus 6B (HHV-6 variant B) (strain Z29) Protein U22 (His)
TMPH-01458
Species: HHV-6B
Expression System: in vitro E. coli expression system
Cat No. Product Name
L1110 Microtubule-Targeted Compound Library

155 compounds
A unique collection of 155 microtubule-targeted compounds can be used in HTS and HCS;
L1310 Cytoskeletal Signaling Pathway Compound Library

773 compounds
A unique collection of 773 cytoskeleton-related compounds, can be used for HTS and HCS;
TargetMol