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Microtubule Associated

Microtubule-associated proteins (MAPs) are proteins that interact with the microtubules of the cellular cytoskeleton. MAPs bind to the tubulin subunits that make up microtubules to regulate their stability. A large variety of MAPs have been identified in many different cell types, and they have been found to carry out a wide range of functions. These include both stabilizing and destabilizing microtubules, guiding microtubules towards specific cellular locations, cross-linking microtubules and mediating the interactions of microtubules with other proteins in the cell.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T4968 KHS 101 1262770-73-9 98.00%
KHS 101
KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.
T5749 10-Deacetyl-7-xylosyl paclitaxel 90332-63-1 98%
10-Deacetyl-7-xylosyl paclitaxel
10-Deacetyl-7-xylosyl paclitaxel (7-Xylosyl-10-deacetyltaxol) is a Paclitaxel derivative with improved pharmacological features and higher water solubility,used ...
T6071 Parbendazole 14255-87-9 98%
Parbendazole
Parbendazole (SKF 29044) is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine. It finds applications in control ...
T5860 CK-869 388592-44-7 98%
CK-869
CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor(IC50 of 7 μM),and is useful tools for the investigation of the Arp2/3 complex.
T5699 SSE15206 1370046-40-4 98%
SSE15206
SSE15206 is a microtubule polymerization inhibitor that overcomes multidrug resistance. Causes aberrant mitosis resulting in G2/M arrest due to incomplete spindl...
T13298 Verubulin hydrochloride 917369-31-4 97.93%
Verubulin hydrochloride
Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxic ac...
T3330L Cis-trismethoxy Resveratrol 94608-23-8 97.55%
cis-trismethoxy Resveratrol
cis-trismethoxy Resveratrol ((Z)-3,5,4'-Trimethoxystilbene) inhibits tubulin polymerization (IC50 = 4 μM) and has anti-mitotic effects.
T14350 Soblidotin 149606-27-9 97.48%
Soblidotin
Soblidotin (TZT-1027) (Auristatin PE) is an inhibitor of tubulin polymerization. It is also a novel synthetic Dolastatin 10 derivative.
T8342 BRD9876 32703-82-5 97.22%
BRD9876
BRD9876 is a selective inhibitor of MM1S growth.
T14694 BNC105 945771-74-4 96.57%
BNC105
BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.
T4451 Estramustine phosphate sodium 52205-73-9 96.44%
Estramustine phosphate sodium
Estramustine phosphate sodium (Ro 21-8837/001) is an antimicrotubule chemotherapy agent; arrests prostate cancer cells in the G2/M phase of the cell cycle.
T1382 Griseofulvin 126-07-8 95.83%
Griseofulvin
Griseofulvin (Fulvicin) is an antifungal agent used in the treatment of TINEA infections.
T62899 Tau-aggregation and neuroinflammation-IN-1 2175953-98-5 100%
Tau-aggregation and neuroinflammation-IN-1
Tau-aggregation and neuroinflammation-IN-1 is a potent inhibitor of tau protein aggregates, showing significant inhibitory activity against AcPHF6 and full-lengt...
T15236 Entasobulin 501921-61-5 100%
Entasobulin
Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.
T22661 CHM-1 154554-41-3 100%
CHM-1
CHM-1 is an inducer of apoptosis, and displays potent antitumor ability in human hepatocellular carcinoma by activation of Cdc2 kinase activity. CHM-1 inhibits t...
T60757 SB-216 2756818-39-8 100%
SB-216
SB-216 is able to be used for the research of cancer which is a potent inhibitor of tubulin polymerization. SB-216 exhibits strong antiproliferative potency in ...
T5007 Benproperine phosphate 19428-14-9 100%
Benproperine phosphate
Benproperine phosphate (Pirexyl phosphate) is a cough suppressant.
T39994 Sovilnesib 2410796-79-9 98%
Sovilnesib
Sovilnesib is a kinesin-like protein KIF18A inhibitor (WO2020132648). Sovilnesib can be used for the cancer research.
T0968 Paclitaxel 33069-62-4 98%
Paclitaxel
Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest...
T3256 MMAF 745017-94-1 98%
MMAF
MMAF (MonoMethyl auristatin F), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.
KHS 101
T4968
KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.
10-Deacetyl-7-xylosyl paclitaxel
T5749
10-Deacetyl-7-xylosyl paclitaxel (7-Xylosyl-10-deacetyltaxol) is a Paclitaxel derivative with improved pharmacological features and higher water solubility,used ...
Parbendazole
T6071
Parbendazole (SKF 29044) is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine. It finds applications in control ...
CK-869
T5860
CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor(IC50 of 7 μM),and is useful tools for the investigation of the Arp2/3 complex.
SSE15206
T5699
SSE15206 is a microtubule polymerization inhibitor that overcomes multidrug resistance. Causes aberrant mitosis resulting in G2/M arrest due to incomplete spindl...
Verubulin hydrochloride
T13298
Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxic ac...
cis-trismethoxy Resveratrol
T3330L
cis-trismethoxy Resveratrol ((Z)-3,5,4'-Trimethoxystilbene) inhibits tubulin polymerization (IC50 = 4 μM) and has anti-mitotic effects.
Soblidotin
T14350
Soblidotin (TZT-1027) (Auristatin PE) is an inhibitor of tubulin polymerization. It is also a novel synthetic Dolastatin 10 derivative.
BRD9876
T8342
BRD9876 is a selective inhibitor of MM1S growth.
BNC105
T14694
BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.
Estramustine phosphate sodium
T4451
Estramustine phosphate sodium (Ro 21-8837/001) is an antimicrotubule chemotherapy agent; arrests prostate cancer cells in the G2/M phase of the cell cycle.
Griseofulvin
T1382
Griseofulvin (Fulvicin) is an antifungal agent used in the treatment of TINEA infections.
Tau-aggregation and neuroinflammation-IN-1
T62899
Tau-aggregation and neuroinflammation-IN-1 is a potent inhibitor of tau protein aggregates, showing significant inhibitory activity against AcPHF6 and full-lengt...
Entasobulin
T15236
Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.
CHM-1
T22661
CHM-1 is an inducer of apoptosis, and displays potent antitumor ability in human hepatocellular carcinoma by activation of Cdc2 kinase activity. CHM-1 inhibits t...
SB-216
T60757
SB-216 is able to be used for the research of cancer which is a potent inhibitor of tubulin polymerization. SB-216 exhibits strong antiproliferative potency in ...
Benproperine phosphate
T5007
Benproperine phosphate (Pirexyl phosphate) is a cough suppressant.
Sovilnesib
T39994
Sovilnesib is a kinesin-like protein KIF18A inhibitor (WO2020132648). Sovilnesib can be used for the cancer research.
Paclitaxel
T0968
Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest...
MMAF
T3256
MMAF (MonoMethyl auristatin F), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.
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TargetMol