T6834 |
FCCP
|
370-86-5
|
99.5%
|
|
FCCP (Trifluoromethoxy carbonylcyanide phenylhydrazone), a potent uncoupler of oxidative phosphorylation in mitochondria, transport protons across cell membranes...
|
T2970 |
Rotenone
|
83-79-4
|
99.48%
|
|
Rotenone (Rotocide) is a botanical insecticide that is an inhibitor of mitochondrial electron transport. Rotenone is widely distributed in the Leguminosae (Papil...
|
T9031 |
MCU-i4
|
371924-24-2
|
99.45%
|
|
MCU-i4 is a novel negative modulator of the MCU, binding MICU1 and impairing muscle cell growth.
|
T2607 |
MSDC 0160
|
146062-49-9
|
99.45%
|
|
MSDC 0160 (CAY10415) is a prototype mTOT-modulating insulin sensitizer being used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease.
|
T1634 |
Glibenclamide
|
10238-21-8
|
99.39%
|
|
Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.
|
TN1362 |
Afzelin
|
482-39-3
|
99.38%
|
|
Afzelin (Kaempferol-3-O-rhamnoside) has several cellular activities such as DNA-protective, antibacterial, antioxidant, and anti-inflammatory as well as UV-absor...
|
T16342 |
KL1333
|
1800405-30-4
|
99.27%
|
|
KL1333 (NQO1 activator 1) enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. Elevated NAD+ levels trigger the activation of SIRT1 and...
|
T8433 |
HQNO
|
341-88-8
|
99.23%
|
|
HQNO is a natural product isolated from P. aeruginosa,and is a potent inhibitor of electron transport chain(Kd of 64 nM for complex III). It also is a potent mit...
|
T2498 |
Adjudin
|
252025-52-8
|
99.05%
|
|
Adjudin (AF-2364) is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway.
|
T9235 |
GW604714X
|
853953-65-8
|
99.03%
|
|
GW604714X (2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]-) were found to be potent inhibitors of mitoch...
|
T77621 |
Z16078526
|
852222-94-7
|
98.93%
|
|
Z16078526 induces endogenous Ucp1 expression, promotes p38 MAPK phosphorylation and lipolysis in primary mouse brown adipocytes. Z16078526 activates thermogenic ...
|
T4446 |
Tebufenpyrad
|
119168-77-3
|
98.92%
|
|
Tebufenpyrad (Comanche) (mitochondrial complex-1 inhibitors) is an agro-chemically important acaricide that functions like the known mitochondrial toxicant roten...
|
T0412 |
Idebenone
|
58186-27-9
|
98.76%
|
|
Idebenone (CV-2619) is a synthetic analogue of ubiquinone (Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC)....
|
T9774 |
BAY-179
|
2764880-87-5
|
98.75%
|
|
BAY-179 is a potent, selective, species cross-reactive complex I inhibitor for the study of cancer.
|
T7081 |
CCCP
|
555-60-2
|
98.55%
|
|
CCCP (Carbonyl Cyanide m-Chlorophenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. CCCP inhibits the ...
|
T19428 |
Mito-TEMPO
|
1334850-99-5
|
98.5%
|
|
Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic. Mito-TEMPO with superoxide and alkyl radical scavenging properties.
|
T8308 |
NL-1
|
188532-26-5
|
98.42%
|
|
NL-1 is a mitoNEET inhibitor with antileukemic effect.
|
T0200 |
α-Lipoic Acid
|
1077-28-7
|
98.39%
|
|
α-Lipoic Acid (DL-α-Lipoic acid) an octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is bio...
|
T5363 |
Tempo
|
2564-83-2
|
98.35%
|
|
Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a stru...
|
T8841 |
IMT1
|
2304621-31-4
|
98.14%
|
|
IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.
|