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Cat No. | Product Name | Synonyms | Targets |
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T7147 | Valbenazine | NBI-98854 | Monoamine Transporter |
Valbenazine (NBI-98854), a highly selective vesicular monoamine transporter 2(VMAT2) inhibitor, is approved for the treatment of tardive dyskinesia. | |||
T22714 | Decynium 22 | Others | |
Decynium 22 is a plasma membrane monoamine transporter (PMAT) inhibitor | |||
T23070 | Nisoxetine hydrochloride | Sodium Channel , Monoamine Transporter , Norepinephrine | |
Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor | |||
T1993 | J-147 | J147 | Epigenetic Reader Domain , Dopamine Receptor , Monoamine Oxidase |
J-147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate... | |||
T0719 | Tetrabenazine | Xenazine,Ro 1-9569 | Others , Dopamine Receptor , Monoamine Transporter |
Tetrabenazine (Ro 1-9569) is a drug formerly used as an antipsychotic and treatment of various movement disorders. Tetrabenazine blocks neurotransmitter uptake into adrenergic storage vesicles and has been used as a high... | |||
T3534 | Tetrabenazine Racemate | Nitoman,Ro 1-9569 Racemate,Rubigen,TETRABENAZINE | Monoamine Transporter |
Tetrabenazine Racemate (Rubigen) is a selective and reversible inhibitor of vesicular monoamine transporter-2 (VMAT-2). Tetrabenazine Racemate blocks neurotransmitter uptake into adrenergic storage vesicles and has been ... | |||
T7563 | NBI-98782 | (+)-α-Dihydrotetrabenazine,(+)-α-DHTBZ,(+)-DTBZ | Monoamine Transporter |
NBI-98782 ((+)-α-DHTBZ) is an inhibtior of vesicular monoamine transporter (VMAT2) (Ki: 0.97 nM) | |||
T13134 | (+)-Tetrabenazine | (+)-TBZ,(3R,11bR)-Tetrabenazine,(3R,11bR)-TBZ | Monoamine Transporter |
(+)-Tetrabenazine ((3R,11bR)-Tetrabenazine) is a reversible vesicular monoamine transporter 2 (VMAT-2) inhibitor, inhibits transport by VMAT2 with 10-fold greater potency than transport by VMAT1. | |||
T7651 | Rose Bengal sodium | Rose Bengal | Influenza Virus , Monoamine Transporter |
Rose Bengal sodium is a potent inhibitor of VGlut and vesicular monoamine transporter (VMAT) (Ki of 19 and 64 nM for VGlut andVMAT, respectively) | |||
T13133 | Tetrabenazine Metabolite | (-)-β-Dihydrotetrabenazine,(-)-β-HTBZ | Monoamine Transporter |
Tetrabenazine Metabolite ((-)-β-HTBZ), a vesicles monoamine transporter 2 (VMAT2) inhibitor, is an active metabolite of Tetrabenazine. Tetrabenazine Metabolite has a high affinity for VMAT2 with a Ki of 13.4 nM. Tetraben... | |||
T22781L | FFN 511 hydrochloride | FFN 511 hydrochloride(1004548-96-2 Free base) | |
FFN 511 hydrochloride is a fluorescent pseudo-neurotransmitters (FFNs) targeting neuronal vesicular monoamine transporter 2 (VMA T2).FFN 511 hydrochloride inhibits the binding of 5-hydroxytryptamine to VMA T2-containing ... | |||
T25750 | Lobelane Hydrochloride | ||
Lobelane Hydrochloride is a vesicular monoamine transporter-2 (VMAT2) inhibitor. | |||
T68488 | Indatraline | ||
Indatraline is a nonselective monoamine transporter inhibitor. | |||
T31790 | FFN200 dihydrochloride | FFN200 HCl,FFN200,FFN 200,FFN-200 | |
FFN200 is a vesicular monoamine transporter 2 (VMAT2) substrate that selectively traces monoamine exocytosis in both neuronal cell culture and brain tissue. | |||
T31791 | FFN246 HCl | FFN 246,FFN246 hydrochloride,FFN246,FFN-246 | |
FFN246 is a fluorescent substrate for both the serotonin transporter and the vesicular monoamine transporter 2 (VMAT2). | |||
T70322 | Valbenazine dihydrochloride | ||
Valbenazine dihydrochloride inhibits vesicular monoamine transporter 2 (VMAT2); used to treat tardive dyskinesia. | |||
T36949 | Niaprazine | 5-HT Receptor , Adrenergic Receptor , Histamine Receptor | |
Niaprazine is a histamine H1-receptor antagonist with marked sedative properties. Niaprazine has antihistamine and antiserotonin activities and can be used for sleep disorder research[1][2]. Niaprazine exhibits a low aff... | |||
T24941 | VMAT2-IN-I HCl | VMAT2 IN I Hydrochloride,VMAT2-IN-I Hydrochloride,VMAT2INI Hydrochloride | |
VMAT2-IN-I HCl is an inhibitor of vesicular monoamine transporter-2. It also has 15- fold greater affinity than GZ- 793A. | |||
T23629 | Adam I-123 | Adam I 123,Adam I123 | |
Adam I-123 is a radiopharmaceutical containing the serotonin transporter (SERT) ligand, with SERT-binding and radioisotope activities. SERT is a monoamine transporter protein found in the membranes of neurons and platele... | |||
T27689 | JNJ-7925476 HCl | JNJ-7925476,JNJ7925476,JNJ 7925476 | |
JNJ-7925476 HCl is a triple monoamine uptake inhibitor. JNJ-7925476 Salt blocks the dopamine transporter (DAT), norepinephrine transporter (NET) and serotonin transporter (SERT) in the central nervous system. The ED(50) ... | |||
T12190 | Trans (2,3)-Dihydrotetrabenazine | (2R,3R,11bR)-rel-DHTBZ,(2R,3R,11bR)-rel-Dihydrotetrabenazine | Others |
Trans (2,3)-Dihydrotetrabenazine is a Tetrabenazine metabolite, shows inhibition activity on vesicular monoamine transporter (VMAT2). | |||
T22452 | Valbenazine tosylate | NBI-98854 | Monoamine Transporter |
Valbenazine tosylate, the tosylate salt of valbenazine, is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no significant binding to VAMT1(Ki<10 μM). | |||
T78684 | FFN246 | 5-HT Receptor | |
FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation and emission spectra at 392/427 nm, respectively. It serves to label... | |||
T9300 | DiPT | ||
DiPT is an agonist at the 5HT2A receptor and a partial agonist at the 5HT1A receptor, and inhibits the transport of 5-hydroxytryptamine transporter and vesicular monoamine transporter 2. | |||
T71772 | Bicifadine free base | ||
Bicifadine, also known as DOV-220075, CL 220,075, is a SNDR inhibitor potentially for the treatment of lower back pain. Bicifadine has a non-opioid, non-NSAID mechanism for the treatment of pain, which should have less ... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0791 | Reserpine | Serpalan,Serpasil,Serpivite | Others , Potassium Channel , MRP , Monoamine Transporter , Autophagy |
Reserpine (Serpalan) is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotoni... | |||
T3933 | Jatrorrhizine | Yatrorizine,neprotin | MAO , 5-HT Receptor , Antibacterial , AChE |
Jatrorrhizine (neprotin) is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal activity. It binds and noncompetitively inhibits mo... |