T0679 |
Ketoconazole |
Ketoconazole, a CYP3A4 inhibitor, is an imidazole anti-fungal agent. |
T6099 |
GKT137831 |
GKT137831 is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor. |
T8107 |
GLX351322 |
GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM. |
T8408 |
GKT136901 |
GKT136901 is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite |
TN1208 |
2-Amino-3-carboxy-1,4-naphthoquinone |
2-Amino-3-carboxy-1,4-naphthoquinone is a novel growth stimulator for bifidobacteria, it affects the end-product profile of bifidobacteria through the mediated ...
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TN1503 |
Cistanoside F |
Cistanoside F shows vasorelaxant, and antioxidative effects, it shows a strong free radical scavenging activity on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical ...
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TN1645 |
Flavokawain C |
Flavokawain C is a melanogenesis inhibitor, it inhibited melanogenesis with IC50 values of 6.9 μM. Flavokawain C has anti-tumor activity, it inhibited cell cyc...
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TN2036 |
Paeonilactone B |
Paeonilactone B is a natural product from Paeonia albiflora. |
TN2126 |
Quercetin-3-O-glucose-6''-acetate |
Quercetin-3-O-glucose-6''-acetate is a NADPH oxidase inhibitor, it has antioxidant capacity. |
TN1542 |
Cycloheterophyllin |
Cycloheterophyllin has an antioxidant effect, it is a photoprotective agent that inhibits ultraviolet A (UVA)-induced oxidative stress and damage, and could be ...
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T10354 |
APX-115 |
APX-115 (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 ef...
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T10353 |
APX-115 free base |
APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, a...
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TJS1779 |
Protosappanin A |
Protosappanin A has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB infl...
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TN2766 |
2'-Hydroxydaidzein |
2'-Hydroxygenistein is an isoflavonoid phytoalexin, it suppresses chemical mediators in inflammatory cells, may have value in treatment and prevention of centra...
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TN3069 |
4beta-Carboxy-19-nortotarol |
4 beta-Carboxy-19-nortotarol can inhibit microsomal lipid peroxidation induced by Fe(III)-ADP/NADPH and mitochondrial lipid peroxidation induced by Fe(III)-ADP/...
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TMA0033 |
5'-Demethylaquillochin |
5'-Demethylaquillochin and its isomer from the dichloromethane extract of E. cavaleriei have potential as chemopreventive agents through induction of detoxifica...
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TN3112 |
5-Heneicosylresorcinol |
5-Heneicosylresorcinol shows inhibitory effects on the release of β-hexosaminidase from RBL-2H3 cells, it also prevents triglyceride accumulation in 3T3-L1 cel...
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TN3294 |
8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate |
8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes. |
TN3300 |
8alpha-Tigloyloxyhirsutinolide 13-O-acetate |
8alpha-Tigloyloxyhirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes. 8alpha-Tigloyloxyhirsutinolide 13-O-acetate has...
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TN3469 |
Aucuparin |
Aucuparin is a phytoalexin, it shows significant scavenging activity by the ABTS and FRAP assays. Aucuparin exhibits potent inhibitory activity against fMLP-ind...
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TN3627 |
Chalepensin |
Chalepensin behaves as an energy transfer inhibitor at low concentration, it inhibits multiple P450s and that epoxidation activity is crucial for the potential ...
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TN4227 |
Horminone |
Horminone has antimicrobial activity, it can inhibit the protein synthesis in several types of bacteria; it can inhibit the in vitro growth of Trypanosoma cruzi...
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TN4317 |
Isopedicin |
Isopedicin has anti-inflammatory functions, it inhibits the O(2)(*)(-) production in human neutrophils by an elevation of cellular cAMP and activation of PKA th...
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TN4635 |
Neoechinulin A |
Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, it may block t...
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TN4800 |
Pisatin |
Pisatin is an isoflavonoid phytoalexin synthesized by pea (Pisum sativum L.). |
TN4889 |
(R)-Reticuline |
(R)-Reticuline is the biosynthetic precursor of the morphinan alkaloids. |
TN4905 |
Rehmannic acid |
Rehmannic acid and oleanolic acetate inhibit succinoxidase activity. Both Rehmannic acid and Icterogenin are potent uncouplers, abolishing the phosphate uptake,...
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TMA1570 |
Sappanone A |
Sappanone A is the first homoisoflavanone to be discovered with melanogenesis inhibitory activity. It exerts its anti-inflammatory effect by modulating the Nrf2...
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TN5050 |
Sprengerinin C |
Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can s...
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TN5156 |
Totaradiol |
Totaradiol shows antioxidant activity, it can inhibit linoleic acid autoxidation but not generation of superoxide anion. Totaradiol exhibits cytotoxic activity ...
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TN5243 |
Vitexilactone |
Vitexilactone is a HIV-1 reverse transcriptase inhibitor in virtual screening against Indonesian Herbal Database using AutoDock4 performed on HIV-1 reverse tran...
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TN5278 |
Zederone |
Zederone has anti-bacterial activity,it inhibits gram-positive bacteria activity. Zederone induces hepatotoxicity implicated the induction of Cyps, which leads ...
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