NADPH-oxidase

NADPH oxidase (nicotinamide adenine dinucleotide phosphate oxidase) is a membrane-bound enzyme complex that faces the extracellular space. It can be found in the plasma membrane as well as in the membranes of phagosomes used by neutrophil white blood cells to engulf microorganisms.

Cat No.	product name
T0679	Ketoconazole	Ketoconazole, a CYP3A4 inhibitor, is an imidazole anti-fungal agent.
T10353	APX-115 free base	APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase （Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, a...
T10354	APX-115	APX-115 (Ewha-18278) is a potent, orally active pan NADPH oxidase （Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 ef...
T6099	GKT137831	GKT137831 is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.
T8107	GLX351322	GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.
T8408	GKT136901	GKT136901 is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite
TJS1779	Protosappanin A	Protosappanin A has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IÎºB/NF-ÎºB infl...
TMA0033	5'-Demethylaquillochin	5'-Demethylaquillochin and its isomer from the dichloromethane extract of E. cavaleriei have potential as chemopreventive agents through induction of detoxifica...
TMA1570	Sappanone A	Sappanone A is the first homoisoflavanone to be discovered with melanogenesis inhibitory activity. It exerts its anti-inflammatory effect by modulating the Nrf2...
TN1208	2-Amino-3-carboxy-1,4-naphthoquinone	2-Amino-3-carboxy-1,4-naphthoquinone is a novel growth stimulator for bifidobacteria, it affects the end-product profile of bifidobacteria through the mediated ...
TN1503	Cistanoside F	Cistanoside F shows vasorelaxant, and antioxidative effects, it shows a strong free radical scavenging activity on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical ...
TN1542	Cycloheterophyllin	Cycloheterophyllin has an antioxidant effect, it is a photoprotective agent that inhibits ultraviolet A (UVA)-induced oxidative stress and damage, and could be ...
TN1645	Flavokawain C	Flavokawain C is a melanogenesis inhibitor, it inhibited melanogenesis with IC50 values of 6.9 μM. Flavokawain C has anti-tumor activity, it inhibited cell cyc...
TN2036	Paeonilactone B	Paeonilactone B is a natural product from Paeonia albiflora.
TN2126	Quercetin-3-O-glucose-6''-acetate	Quercetin-3-O-glucose-6''-acetate is a NADPH oxidase inhibitor, it has antioxidant capacity.
TN2766	2'-Hydroxydaidzein	2'-Hydroxygenistein is an isoflavonoid phytoalexin, it suppresses chemical mediators in inflammatory cells, may have value in treatment and prevention of centra...
TN3069	4beta-Carboxy-19-nortotarol	4 beta-Carboxy-19-nortotarol can inhibit microsomal lipid peroxidation induced by Fe(III)-ADP/NADPH and mitochondrial lipid peroxidation induced by Fe(III)-ADP/...
TN3112	5-Heneicosylresorcinol	5-Heneicosylresorcinol shows inhibitory effects on the release of β-hexosaminidase from RBL-2H3 cells, it also prevents triglyceride accumulation in 3T3-L1 cel...
TN3294	8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate	8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes.
TN3300	8alpha-Tigloyloxyhirsutinolide 13-O-acetate	8alpha-Tigloyloxyhirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes. 8alpha-Tigloyloxyhirsutinolide 13-O-acetate has...
TN3469	Aucuparin	Aucuparin is a phytoalexin, it shows significant scavenging activity by the ABTS and FRAP assays. Aucuparin exhibits potent inhibitory activity against fMLP-ind...
TN3627	Chalepensin	Chalepensin behaves as an energy transfer inhibitor at low concentration, it inhibits multiple P450s and that epoxidation activity is crucial for the potential ...
TN4227	Horminone	Horminone has antimicrobial activity, it can inhibit the protein synthesis in several types of bacteria; it can inhibit the in vitro growth of Trypanosoma cruzi...
TN4317	Isopedicin	Isopedicin has anti-inflammatory functions, it inhibits the O(2)(*)(-) production in human neutrophils by an elevation of cellular cAMP and activation of PKA th...
TN4635	Neoechinulin A	Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-ÎºB and p38 MAPK pathways, it may block t...
TN4800	Pisatin	Pisatin is an isoflavonoid phytoalexin synthesized by pea (Pisum sativum L.).
TN4889	(R)-Reticuline	(R)-Reticuline is the biosynthetic precursor of the morphinan alkaloids.
TN4905	Rehmannic acid	Rehmannic acid and oleanolic acetate inhibit succinoxidase activity. Both Rehmannic acid and Icterogenin are potent uncouplers, abolishing the phosphate uptake,...
TN5050	Sprengerinin C	Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can s...
TN5156	Totaradiol	Totaradiol shows antioxidant activity, it can inhibit linoleic acid autoxidation but not generation of superoxide anion. Totaradiol exhibits cytotoxic activity ...
TN5243	Vitexilactone	Vitexilactone is a HIV-1 reverse transcriptase inhibitor in virtual screening against Indonesian Herbal Database using AutoDock4 performed on HIV-1 reverse tran...
TN5278	Zederone	Zederone has anti-bacterial activity,it inhibits gram-positive bacteria activity. Zederone induces hepatotoxicity implicated the induction of Cyps, which leads ...