NADPH

Nicotinamide adenine dinucleotide phosphate, abbreviated NADP+ or, in older notation, TPN (triphosphopyridine nucleotide), is a cofactor used in anabolic reactions, such as the Calvin cycle and lipid and nucleic acid syntheses, which require NADPH as a reducing agent. It is used by all forms of cellular life.NADPH is the reduced form of NADP+. NADP+ differs from NAD+ in the presence of an additional phosphate group on the 2' position of the ribose ring that carries the adenine moiety. This extra phosphate is added by NAD+ kinase and removed by NADP+ phosphatase.

Cat. No.	Product name	CAS No.	Purity
T15429	GSK2194069	1332331-08-4	98%
T15429	GSK2194069 is an active β-keto reductase (KR)-specific inhibitor of fatty acid synthase (FASN) with an IC50 of 7.7 nM in an assay for the detection of released C...
T16361	Nucleocidin	24751-69-7	98%
T16361	Nucleocidin, an antitrypanosomal antibiotic, inhibits the transfer of labeled amino acids from S-RNA to protein.
TN3806	Dehydroglyasperin C	199331-35-6	98%
TN3806	Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemop...
T1079	Metronidazole	443-48-1	99.98%
T1079	Metronidazole (Metronidazol) is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.
T7149	S29434	874484-20-5	99.92%
T7149	S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).
T64376	Casein kinase 1δ-IN-9	854355-54-7	99.74%
T64376	Casein kinase 1δ-IN-9 is a Quinone reductase 2 inhibitor with IC50 of 0.6μM.
T6391	Apocynin	498-02-2	99.71%
T6391	Apocynin (NSC 2146) is a specific NADPH-oxidase inhibitor (IC50: 10 μM).
T8107	GLX351322	835598-94-2	99.7%
T8107	GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.
T1558	Resveratrol	501-36-0	99.53%
T1558	Resveratrol (SRT 501) is a polyphenolic natural product, a plant antitoxin with antioxidant and chemopreventive activities. Resveratrol has a wide range of targe...
T14151	AKR1C1-IN-1	4906-68-7	99.44%
T14151	AKR1C1-IN-1 is a human 20α-hydroxysteroid dehydrogenase (AKR1C1) inhibitor (Ki: 4 nM for AKR1C1).
T67846	AKR1C3-IN-9		99.41%
T67846	AKR1C3-IN-9 is a selective Aldo-keto Reductase 1C3 (AKR1C3) inhibitor (IC50= 8.92 nM). AKR1C3-IN-9 can significantly reverse the Doxorubicin (DOX) resistance in ...
T61316	HTS07545	118666-03-8	99.32%
T61316	HTS07545 is a potent sulfide:quinone oxidoreductase inhibitor (IC50: 30 nM).HTS07545 reduces the rate of hydrogen sulfide (H2S) decomposition.HTS07545 has been u...
T16342	KL1333	1800405-30-4	99.27%
T16342	KL1333 (NQO1 activator 1) enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. Elevated NAD+ levels trigger the activation of SIRT1 and...
T0816	Acetohexamide	968-81-0	99.19%
T0816	Acetohexamide (Acetohexamid) is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. It inhibits sulfonylurea receptor 1 (SUR1) link...
T10353	APX-115 free base	1270084-92-8	99.03%
T10353	APX-115 free base (Ewha-18278 free base) (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM ...
T15433	GSK2795039	1415925-18-6	98.68%
T15433	GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2...
T8408	GKT136901	955272-06-7	98.29%
T8408	GKT136901 (AK120765) is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite
T13799	NQO1 substrate	2304503-05-5	98.02%
T13799	NQO1 substrate is a highly potent NQO1 substrate with potential antitumor activity for leukemia research.
T7406	AKR1C3-IN-1	327092-81-9	98%
T7406	AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).
T7191	Diphenyleneiodonium chloride	4673-26-1	98%
T7191	Diphenyleneiodonium chloride (DPI)(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 μM, respectively),and displays broad-spectrum...