Home Tools
Log in
Cart

NADPH-oxidase

NADPH oxidase (nicotinamide adenine dinucleotide phosphate oxidase) is a membrane-bound enzyme complex that faces the extracellular space. It can be found in the plasma membrane as well as in the membranes of phagosomes used by neutrophil white blood cells to engulf microorganisms.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
TN4635 Neoechinulin A 51551-29-2 98%
Neoechinulin A
Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, it may block the ...
TN3469 Aucuparin 3687-28-3 99.81%
Aucuparin
Aucuparin (2,6-dimethoxy-4-phenylphenol) is a plant antibiotic with anti-inflammatory activity. Aucuparin inhibited pulmonary fibrosis in mouse models induced by...
T8107 GLX351322 835598-94-2 99.7%
GLX351322
GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.
T10354 APX-115 1395946-75-4 99.68%
APX-115
APX-115 (Ewha-18278) (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX...
T6099 Setanaxib 1218942-37-0 99.66%
Setanaxib
Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.
T0679 Ketoconazole 65277-42-1 99.62%
Ketoconazole
Ketoconazole (R-41400), a CYP3A4 inhibitor, is an imidazole anti-fungal agent.
T25952 Phox-I2 353495-22-4 99.52%
Phox-I2
Phox-I2 is an NOX2-specific inhibitor. Phox-I2 reverts ROS-accumulation and leads to refusion of mitochondrial networks.
T10353 APX-115 free base 1270084-92-8 99.03%
APX-115 free base
APX-115 free base (Ewha-18278 free base) (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM ...
T29097 VAS 3947 869853-70-3 98.44%
VAS 3947
VAS 3947 is a specific inhibitor of NADPH oxidase (NOX).VAS 3947 has a potent anti-platelet effect, inducing apoptosis through UPR activation, mainly due to prot...
T8408 GKT136901 955272-06-7 98.29%
GKT136901
GKT136901 (AK120765) is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite
T22990 ML-090 531-46-4 98.23%
ML-090
ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM).
T9948 NecroX-7 1120332-55-9 98.08%
NecroX-7
NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen t...
TN2126 Quercetin-3-O-glucose-6''-acetate 54542-51-7 97.48%
Quercetin-3-O-glucose-6''-acetate
Quercetin-3-O-glucose-6''-acetate (6"-O-Acetylisoquercitrin) is an inhibitor of NADPH oxidase. Quercetin-3-O-glucose-6''-acetate has antioxidant activities.
TP1886L1 NoxA1ds acetate(1435893-78-9 free base) TP1886L1 96.92%
NoxA1ds acetate(1435893-78-9 free base)
NoxA1ds acetate is a potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 : 20 nM). Exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxida...
TJS1779 Protosappanin A 102036-28-2 100%
Protosappanin A
Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inf...
Neoechinulin A
TN4635
Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, it may block the ...
Aucuparin
TN3469
Aucuparin (2,6-dimethoxy-4-phenylphenol) is a plant antibiotic with anti-inflammatory activity. Aucuparin inhibited pulmonary fibrosis in mouse models induced by...
GLX351322
T8107
GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.
APX-115
T10354
APX-115 (Ewha-18278) (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX...
Setanaxib
T6099
Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.
Ketoconazole
T0679
Ketoconazole (R-41400), a CYP3A4 inhibitor, is an imidazole anti-fungal agent.
Phox-I2
T25952
Phox-I2 is an NOX2-specific inhibitor. Phox-I2 reverts ROS-accumulation and leads to refusion of mitochondrial networks.
APX-115 free base
T10353
APX-115 free base (Ewha-18278 free base) (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM ...
VAS 3947
T29097
VAS 3947 is a specific inhibitor of NADPH oxidase (NOX).VAS 3947 has a potent anti-platelet effect, inducing apoptosis through UPR activation, mainly due to prot...
GKT136901
T8408
GKT136901 (AK120765) is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite
ML-090
T22990
ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM).
NecroX-7
T9948
NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen t...
Quercetin-3-O-glucose-6''-acetate
TN2126
Quercetin-3-O-glucose-6''-acetate (6"-O-Acetylisoquercitrin) is an inhibitor of NADPH oxidase. Quercetin-3-O-glucose-6''-acetate has antioxidant activities.
NoxA1ds acetate(1435893-78-9 free base)
TP1886L1
NoxA1ds acetate is a potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 : 20 nM). Exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxida...
Protosappanin A
TJS1779
Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inf...
1 2
TargetMol