TN1077 |
Taraxerol
|
127-22-0
|
98.92%
|
|
Taraxerol(Alnulin) is an anti-inflammatory and anticancer compound derived from dandelion.Taraxerol reduces acute inflammation and induces apoptosis by inhibitin...
|
TN2089 |
Platycodin D3
|
67884-03-1
|
98.91%
|
|
Platycodin D3 is a NF-κB inhibitor, it could as expectorants in diverse inflammatory pulmonary diseases, it can regulate the production and secretion of airway m...
|
TN2244 |
Sulfuretin
|
120-05-8
|
98.91%
|
|
Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its abili...
|
T5S0761 |
Nitidine chloride
|
13063-04-2
|
98.91%
|
|
1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721...
|
T3S1641 |
Esculentoside H
|
66656-92-6
|
98.9%
|
|
Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.
|
T13604 |
CDDO-dhTFEA
|
1191265-33-4
|
98.88%
|
|
CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor. It restores mean art...
|
T2755 |
Rhoifolin
|
17306-46-6
|
98.87%
|
|
Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.
|
T39965 |
NF-κΒ activator 1
|
2387524-59-4
|
98.85%
|
|
NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns. NF-κΒ is widely used in eukaryotic cells as a gene regulating cell proliferati...
|
TN2179 |
Saponarin
|
20310-89-8
|
98.84%
|
|
Saponarin (Petrocomoside) shows in vitro and in vivo hepatoprotective and antioxidant activity against CCl4-induced liver damage.
|
T6561 |
Laquinimod
|
248281-84-7
|
98.84%
|
|
Laquinimod (LAQ) is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral the...
|
T78557 |
HOIPIN-1
|
2470242-33-0
|
98.83%
|
|
HOIPIN-1 (JTP0819958) is a selective and potent inhibitor of linear ubiquitin chain assembly complex (LUBAC) (IC50 >2.8 μM).HOIPIN-1 inhibits LUBAC-mediated NF-k...
|
T2768 |
Saikosaponin A
|
20736-09-8
|
98.76%
|
|
Saikosaponin A has a variety of pharmacological benefits, including antiepileptic, anti-osteoporosis, antioxidant, anti-in ammatory, immunomodulatory, and anti-b...
|
T0907 |
Sulfasalazine
|
599-79-1
|
98.73%
|
|
Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative with affinity for connective tissues containing elastin and formulated as a prodrug
|
T6677 |
Sophocarpine
|
6483-15-4
|
98.67%
|
|
Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.
|
T67790 |
Biricodar dicitrate
|
174254-13-8
|
98.67%
|
|
Biricodar dicitrate (VX-710) is a potent MDR inhibitor with no anticancer activity and can be used to study prostate cancer.
|
TN2080 |
Pinoresinol
|
487-36-5
|
98.67%
|
|
Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, ...
|
T4361 |
CBL0137 hydrochloride
|
1197397-89-9
|
98.59%
|
|
CBL0137 hydrochloride (Curaxin-137 hydrochloride) activates p53 and inhibits NF-kB (EC50: 0.37/0.47 μM) in the cell-based p53 and NF-kB reporter assays, respecti...
|
T1125 |
Shikonin
|
517-89-5
|
98.54%
|
|
Shikonin (Anchusa acid) is a natural product, a TMEM16A chloride channel inhibitor (IC50=6.5 μM) and selective PKM2 inhibitor. Shikonin exhibits antitumor, anti-...
|
T4S0800 |
Demethyleneberberine
|
25459-91-0
|
98.54%
|
|
Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either ...
|
TN1237 |
3-O-Methylgallic acid
|
3934-84-7
|
98.53%
|
|
3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may...
|