T10688 |
Casopitant mesylate |
Casopitant mesylate (GW679769B) is a selective, brain permeable, and orally active antagonist of neurokinin 1 (NK1) receptor. It is a second in the class of ant...
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T10892 |
CS-003 Free base |
CS-003 free base (CS-003) is a triple tachykinin receptor antagonist with high affinity for human (neurokinin) NK1, NK2 and NK3 receptors, with Ki values of 2.3...
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T13329 |
Vofopitant |
Vofopitant is a potent antagonist of the tachykinin NK1 receptor (pKis: 10.6, 9.5, and 9.8 for the human, rat, and ferret NK1 receptor, respectively). |
T13329L |
Vofopitant dihydrochloride |
Vofopitant dihydrochloride is a selective and orally available antagonist of tachykinin neurokinin 1(NK1) receptor (pKi: 9.5 and 10.6 in rat and human membranes...
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T16406 |
Orvepitant maleate |
Orvepitant maleate is an effective, selective, and well-tolerated neurokinin-1 receptor (NK-1) antagonist (pKi: 10.2 for human neurokinin-1 receptor). Orvepitan...
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T1743 |
Aprepitant |
Aprepitant is a Substance P/Neurokinin-1 Receptor Antagonist. The mechanism of action of aprepitant is as a Neurokinin 1 Antagonist, and Cytochrome P450 3A4 Inh...
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T1790 |
Fosaprepitant dimeglumine |
Fosaprepitant Dimeglumine is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Up...
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T19518 |
Physalaemin |
Physalaemin is a non-mammalian tachykinin. |
T3716 |
Rolapitant |
Rolapitant Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor)...
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T3724 |
Rolapitant hydrochloride |
Rolapitant Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor)...
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T6905 |
Netupitant |
Netupitant is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM). |
T7209 |
Maropitant |
Maropitant is a selective neurokinin (NK1) receptor antagonist. |
T7549 |
Talnetant |
Talnetant is a selective, competitive, brain-penetrant NK3 receptor antagonist with the ability to modulate mesolimbic and mesocortical dopaminergic neurotransm...
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T7633 |
Senktide |
Senktide is an agonist of tachykinin NK3 receptor. |
T7828 |
Bhsar-sp |
Bhsar-sp is an agonist of NK1 receptor. |
T8235 |
L-732138 |
L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM) |
T8789 |
N-Acetyl-L-tryptophan |
N-Acetyl-L-tryptophan is an inhibitor of neurokinin 1 receptor (NK1-receptor, NK1R). |
TP1008 |
Neurokinin A |
Neurokinin A (NKA), formerly known as Substance K, is a neurologically active peptide translated from the pre-protachykinin gene. |
TP1008 |
Neurokinin A |
Neurokinin A (NKA), formerly known as Substance K, is a neurologically active peptide translated from the pre-protachykinin gene. |
TP1086 |
Men 10376 TFA(135306-85-3,free) |
Men 10376 TFA is an effective and selective tachykinin nk-2 receptor antagonist with a K I value of 4.4 M for the nk-2 receptor in the small intestine of rats. |
TP1087 |
Substance P |
Substance P (SP) is an undecapeptide (a peptide composed of a chain of 11 amino acid residues) member of the tachykinin neuropeptide family. |
TP1385 |
Neurokinin A(4-10) TFA(97559-35-8 free base) |
Neurokinin A (4-10) TFA is a tachykinin NK2 receptor agonist[1]. |
TP1572 |
GR-73632 |
Potent and selective tachykinin NK1 receptor agonist (EC50 = 2 nM in guinea pig vas deferens). |
TP1772L |
Hemokinin 1 (mouse) acetate(208041-90-1 free base) |
Hemokinin 1 (mouse) acetate is a selective excitogen 1 receptor agonist with a Ki value of 0.175 nM for the human NK1 receptor and 560 nM for the human NK2 rece...
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TP1883 |
[Lys5,MeLeu9,Nle10]-NKA(4-10) |
Highy selective and potent NK2 receptor agonist (IC50 = 6.1 nM). Induces contraction of the rat fundus and bladder (EC50 values are 117 and 10 nM respectively). |