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Opioid Receptor

Opioid receptors belong to the large superfamily of seven transmembrane-spanning (7TM) G protein-coupled receptors (GPCRs). As a class, GPCRs are of fundamental physiological importance mediating the actions of the majority of known neurotransmitters and hormones.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T20166L Deltorphin acetate 98.93%
Deltorphin acetate
Deltorphin acetate is a substance obtained from the skin secretions of a frog, Phyllomedusa bicolor and shows high selectivity and affinity for δ-opioid receptor...
T4411 DAMGO TFA (78123-71-4(Free base)) T4411 98.67%
DAMGO TFA (78123-71-4(Free base))
Potent, selective agonist of Mu-opioid receptor. Antinociceptive. Stimulates calcium-activated adenylyl cyclases related cAMP production. Expresses chemokines an...
TP1793 Nociceptin (1-13), amide 178064-02-3 100%
Nociceptin (1-13), amide
Nociceptin (1-13), amide is a potent ORL1 (OP4) receptor agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain memb...
T7567 Adrenorphin 88377-68-8
Adrenorphin
Adrenorphin (Metorphamide)(3TFA) is an agonist of μ-opioid receptor(Ki :12 nM).
T4633 Asimadoline 153205-46-0
Asimadoline
Asimadoline (EMD-61753) is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt, Germany. Asimadoline was originally develo...
T7404 Dermorphin 77614-16-5
Dermorphin
Dermorphin is agonist of μ-opioid receptor (MOR) agonist.
T11479 GSK1521498 1426543-84-1 98%
GSK1521498
GSK1521498 is a selective antagonist of the μ-opioid receptor (MOR). It is being used for the treatment of disorders of compulsive consumption of food, alcohol, ...
T11478 GSK1521498 free base (hydrochloride) 1007578-24-6 98%
GSK1521498 free base (hydrochloride)
GSK1521498 free base (hydrochloride) is a selective antagonist of the μ-opioid receptor (MOR). It is being used for the treatment of disorders of compulsive cons...
T79060 MOR agonist-1 2305781-14-8 98%
MOR agonist-1
MOR Agonist-1 is a μ-opioid receptor (MOR) agonist noted for its potent analgesic properties and is utilized in research concerning pain and associated disorders...
T79430 μ opioid receptor agonist 3 2378397-91-0 98%
μ opioid receptor agonist 3
Compound 20, identified as μ opioid receptor agonist 3, is a potent µOR agonist that exhibits an EC50 value of 0.87 nM. It holds promise for research into pain m...
T79431 Mu opioid receptor antagonist 7 2378397-30-7 98%
Mu opioid receptor antagonist 7
Compound 24, also known as Mu opioid receptor antagonist 7, is a potent, centrally-acting µ-opioid receptor (µOR) antagonist with an inhibitory concentration (IC...
T79547 MOR agonist-2 98%
MOR agonist-2
Compound 46, designated as MOR agonist-2, serves as a D3R antagonist and a MOR agonist with respective K i values of 7.26 nM and 564 nM. This compound holds pote...
T79848 Icalcaprant 2227384-17-8 98%
Icalcaprant
Icalcaprant is a kappa-opioid receptor antagonist [1].
T80086 DALDA TFA 98%
DALDA TFA
DALDA TFA is a potent, μ-opioid receptor agonist exhibiting high selectivity and an affinity constant (K i) of 1.69 nM. It demonstrates antinociceptive propertie...
T80421 CSD-CH2(1,8)-NH2 98%
CSD-CH2(1,8)-NH2
CSD-CH2(1,8)-NH2 is a selective and competitive kappa-opioid receptor (KOR) antagonist with a K i of 6.8 nM. It inhibits calcium mobilization in dorsal root gang...
T80463 Dynorphin B (1-9) 126050-26-8 98%
Dynorphin B (1-9)
Dynorphin B (1-9), a neuropeptide and the N-terminal cleavage product of dynorphin B, has its formation inhibited by N-ethylmaleimide (NEM), a non-selective cyst...
T80515 β-Endorphin (1-27) (human) 76622-84-9 98%
β-Endorphin (1-27) (human)
β-Endorphin (1-27) (human) is an opioid antagonist that selectively binds to μ-, δ-, and κ-opioid receptors, with dissociation constants (Kis) of 5.31, 6.17, and...
T81938 Leumorphin, human 88846-98-4 98%
Leumorphin, human
Leumorphin, human, is a potent agonist of the kappa opioid receptor (κ opioid receptor) and inhibits the contraction of the guinea pig ileum's myenteric plexus-l...
TP1367L [D-Ala2]leucine-enkephalin acetate TP1367L 98%
[D-Ala2]leucine-enkephalin acetate
[D-Ala2]leucine-enkephalin acetate ([D-Ala2]leucine-enkephalin acetate (64963-01-5 free base)) is a delta opioid agonist used to study the signaling pathway of d...
TN5017 Sideritoflavone 70360-12-2 98%
Sideritoflavone
Sideritoflavone has anti-inflammatory effect, it is a selective inhibitor of lipoxygenase activity in vitro.
Deltorphin acetate
T20166L
Deltorphin acetate is a substance obtained from the skin secretions of a frog, Phyllomedusa bicolor and shows high selectivity and affinity for δ-opioid receptor...
DAMGO TFA (78123-71-4(Free base))
T4411
Potent, selective agonist of Mu-opioid receptor. Antinociceptive. Stimulates calcium-activated adenylyl cyclases related cAMP production. Expresses chemokines an...
Nociceptin (1-13), amide
TP1793
Nociceptin (1-13), amide is a potent ORL1 (OP4) receptor agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain memb...
Adrenorphin
T7567
Adrenorphin (Metorphamide)(3TFA) is an agonist of μ-opioid receptor(Ki :12 nM).
Asimadoline
T4633
Asimadoline (EMD-61753) is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt, Germany. Asimadoline was originally develo...
Dermorphin
T7404
Dermorphin is agonist of μ-opioid receptor (MOR) agonist.
GSK1521498
T11479
GSK1521498 is a selective antagonist of the μ-opioid receptor (MOR). It is being used for the treatment of disorders of compulsive consumption of food, alcohol, ...
GSK1521498 free base (hydrochloride)
T11478
GSK1521498 free base (hydrochloride) is a selective antagonist of the μ-opioid receptor (MOR). It is being used for the treatment of disorders of compulsive cons...
MOR agonist-1
T79060
MOR Agonist-1 is a μ-opioid receptor (MOR) agonist noted for its potent analgesic properties and is utilized in research concerning pain and associated disorders...
μ opioid receptor agonist 3
T79430
Compound 20, identified as μ opioid receptor agonist 3, is a potent µOR agonist that exhibits an EC50 value of 0.87 nM. It holds promise for research into pain m...
Mu opioid receptor antagonist 7
T79431
Compound 24, also known as Mu opioid receptor antagonist 7, is a potent, centrally-acting µ-opioid receptor (µOR) antagonist with an inhibitory concentration (IC...
MOR agonist-2
T79547
Compound 46, designated as MOR agonist-2, serves as a D3R antagonist and a MOR agonist with respective K i values of 7.26 nM and 564 nM. This compound holds pote...
Icalcaprant
T79848
Icalcaprant is a kappa-opioid receptor antagonist [1].
DALDA TFA
T80086
DALDA TFA is a potent, μ-opioid receptor agonist exhibiting high selectivity and an affinity constant (K i) of 1.69 nM. It demonstrates antinociceptive propertie...
CSD-CH2(1,8)-NH2
T80421
CSD-CH2(1,8)-NH2 is a selective and competitive kappa-opioid receptor (KOR) antagonist with a K i of 6.8 nM. It inhibits calcium mobilization in dorsal root gang...
Dynorphin B (1-9)
T80463
Dynorphin B (1-9), a neuropeptide and the N-terminal cleavage product of dynorphin B, has its formation inhibited by N-ethylmaleimide (NEM), a non-selective cyst...
β-Endorphin (1-27) (human)
T80515
β-Endorphin (1-27) (human) is an opioid antagonist that selectively binds to μ-, δ-, and κ-opioid receptors, with dissociation constants (Kis) of 5.31, 6.17, and...
Leumorphin, human
T81938
Leumorphin, human, is a potent agonist of the kappa opioid receptor (κ opioid receptor) and inhibits the contraction of the guinea pig ileum's myenteric plexus-l...
[D-Ala2]leucine-enkephalin acetate
TP1367L
[D-Ala2]leucine-enkephalin acetate ([D-Ala2]leucine-enkephalin acetate (64963-01-5 free base)) is a delta opioid agonist used to study the signaling pathway of d...
Sideritoflavone
TN5017
Sideritoflavone has anti-inflammatory effect, it is a selective inhibitor of lipoxygenase activity in vitro.
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TargetMol