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Opioid Receptor

Opioid receptors belong to the large superfamily of seven transmembrane-spanning (7TM) G protein-coupled receptors (GPCRs). As a class, GPCRs are of fundamental physiological importance mediating the actions of the majority of known neurotransmitters and hormones.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T23306 Salvinorin A 83729-01-5 99.06%
Salvinorin A
Salvinorin A is a non-nitrogenous κ-opioid selective agonist.
T76341L [DPro10] Dynorphin A (1-11)acetate,porcine 99.05%
[DPro10] Dynorphin A (1-11)acetate,porcine
[DPro10] Dynorphin A (1-11)acetate,porcine is a highly potent κ-opioid receptor agonist with a Ki value of 0.13 nM. [DPro10] Dynorphin A (1-11), porcine is an n-...
T21757 BRL 52537 hydrochloride 112282-24-3 99.04%
BRL 52537 hydrochloride
BRL 52537 hydrochloride is a selective and specific KOR agonist which has been implicated in neuroprotection from ischemic neuronal injury[1]. It is used for res...
T1407 (-)-Menthol 2216-51-5 99.01%
(-)-Menthol
(-)-Menthol (Levomenthol) is a levo isomer of menthol, an organic compound made synthetically or obtained from peppermint or mint oils with flavoring and local a...
T21660L B-Casomorphin (1-3) Acetate T21660L 98.99%
b-Casomorphin (1-3) Acetate
b-Casomorphin (1-3) Acetate is a tri-peptide with an opioid effect.
T4691 Asimadoline hydrochloride 185951-07-9 98.94%
Asimadoline hydrochloride
Asimadoline hydrochloride (EMD-61753 hydrochloride) is a κ-opioid receptor agonist potentially for the treatment of pruritus. Asimadoline hydrochloride has also ...
T23076L Nociceptin (1-7) acetate T23076L 98.92%
Nociceptin (1-7) acetate
Nociceptin (1-7) acetate is a potent agonist of opioid receptor-like 1 (ORL1) receptor. Nociceptin (1-7) combines with nociceptin reduces hyperalgesia and has a...
T39988 6'-GNTI dihydrochloride 2410327-94-3 98.91%
6'-GNTI dihydrochloride
6'-GNTI dihydrochloride is a κ-opioid receptor (KOR) agonist that favors activation of G-protein-mediated signaling over recruitment of β-aspirin 2. 6'-GNTI dihy...
T0963 Naltrexone hydrochloride 16676-29-2 98.9%
Naltrexone hydrochloride
Naltrexone hydrochloride (Naltrexone HCl) is a synthetic opioid antagonist used in the prevention of relapse of opiate addiction and alcoholism.
T4351 DAMGO 78123-71-4 98.83%
DAMGO
DAMGO (DAGO) is an opioid receptor agonist with the ability to affect the locomotive activity in rodents. Possible analgesic agent due to μ-opiod receptor intera...
T22870 IPAG 193527-91-2 98.8%
IPAG
IPAG is a potent σ-receptor antagonist (pKi=4.3). IPAG can induce cell apoptosis.
T20435L Leuphasyl TFA 67586-27-0 98.79%
Leuphasyl TFA
Leuphasyl TFA is an amid peptide, a δ-opioid receptor agonist, is a degradation resistant long-acting Leu-enkephalin analog used to study the signaling pathway o...
T8992 BMS986188 1776115-10-6 98.76%
BMS986188
BMS986188 is a novel Potent and Selective Positive Allosteric Modulator of the delta-Opioid Receptor.
T23074 NNC 63-0532 250685-44-0 98.75%
NNC 63-0532
NNC 63-0532 is a potentnociceptin receptor agonist, Ki=7.3 nM, EC50=305 nM.
T4411 DAMGO TFA (78123-71-4(Free base)) T4411 98.67%
DAMGO TFA (78123-71-4(Free base))
Potent, selective agonist of Mu-opioid receptor. Antinociceptive. Stimulates calcium-activated adenylyl cyclases related cAMP production. Expresses chemokines an...
T8414 SNC 80 156727-74-1 98.67%
SNC 80
SNC 80 (NIH 10815) is a potent, highly selective and non-peptide δ-opioid receptor agonist, Ki = 1.78 nM, IC50 = 2.73 nM. SNC80 also selectively activates μ-δ he...
T23002 ML-335 1069498-96-9 98.52%
ML-335
ML-335 is a μ-δ isomer-targeted agonist, a μOR-δOR-biased ligand that can serve as a scaffold for the development of unique types of (isomer-biased) drugs.ML-335...
T5158 N-Desmethylclozapine 6104-71-8 98.45%
N-Desmethylclozapine
N-Desmethylclozapine (Desmethylclozapine) is an antagonist of serotonin (5-HT) receptor subtype 5-HT2C (IC50: 7.1 nM). It also is an antagonist at dopamine D4 re...
T14835 BTRX-335140 2244614-14-8 98.45%
BTRX-335140
BTRX-335140 (CYM-53093) is a potent and selective, orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC50 value...
T26869 BMS-986122 313669-88-4 98.42%
BMS-986122
BMS-986122 (BMS 986122) is a positive allosteric modulator of μ-opioid receptors that increases β-arrestin recruitment stimulated by endomorphin 1 in U2OS-OPRM1 ...
Salvinorin A
T23306
Salvinorin A is a non-nitrogenous κ-opioid selective agonist.
[DPro10] Dynorphin A (1-11)acetate,porcine
T76341L
[DPro10] Dynorphin A (1-11)acetate,porcine is a highly potent κ-opioid receptor agonist with a Ki value of 0.13 nM. [DPro10] Dynorphin A (1-11), porcine is an n-...
BRL 52537 hydrochloride
T21757
BRL 52537 hydrochloride is a selective and specific KOR agonist which has been implicated in neuroprotection from ischemic neuronal injury[1]. It is used for res...
(-)-Menthol
T1407
(-)-Menthol (Levomenthol) is a levo isomer of menthol, an organic compound made synthetically or obtained from peppermint or mint oils with flavoring and local a...
b-Casomorphin (1-3) Acetate
T21660L
b-Casomorphin (1-3) Acetate is a tri-peptide with an opioid effect.
Asimadoline hydrochloride
T4691
Asimadoline hydrochloride (EMD-61753 hydrochloride) is a κ-opioid receptor agonist potentially for the treatment of pruritus. Asimadoline hydrochloride has also ...
Nociceptin (1-7) acetate
T23076L
Nociceptin (1-7) acetate is a potent agonist of opioid receptor-like 1 (ORL1) receptor. Nociceptin (1-7) combines with nociceptin reduces hyperalgesia and has a...
6'-GNTI dihydrochloride
T39988
6'-GNTI dihydrochloride is a κ-opioid receptor (KOR) agonist that favors activation of G-protein-mediated signaling over recruitment of β-aspirin 2. 6'-GNTI dihy...
Naltrexone hydrochloride
T0963
Naltrexone hydrochloride (Naltrexone HCl) is a synthetic opioid antagonist used in the prevention of relapse of opiate addiction and alcoholism.
DAMGO
T4351
DAMGO (DAGO) is an opioid receptor agonist with the ability to affect the locomotive activity in rodents. Possible analgesic agent due to μ-opiod receptor intera...
IPAG
T22870
IPAG is a potent σ-receptor antagonist (pKi=4.3). IPAG can induce cell apoptosis.
Leuphasyl TFA
T20435L
Leuphasyl TFA is an amid peptide, a δ-opioid receptor agonist, is a degradation resistant long-acting Leu-enkephalin analog used to study the signaling pathway o...
BMS986188
T8992
BMS986188 is a novel Potent and Selective Positive Allosteric Modulator of the delta-Opioid Receptor.
NNC 63-0532
T23074
NNC 63-0532 is a potentnociceptin receptor agonist, Ki=7.3 nM, EC50=305 nM.
DAMGO TFA (78123-71-4(Free base))
T4411
Potent, selective agonist of Mu-opioid receptor. Antinociceptive. Stimulates calcium-activated adenylyl cyclases related cAMP production. Expresses chemokines an...
SNC 80
T8414
SNC 80 (NIH 10815) is a potent, highly selective and non-peptide δ-opioid receptor agonist, Ki = 1.78 nM, IC50 = 2.73 nM. SNC80 also selectively activates μ-δ he...
ML-335
T23002
ML-335 is a μ-δ isomer-targeted agonist, a μOR-δOR-biased ligand that can serve as a scaffold for the development of unique types of (isomer-biased) drugs.ML-335...
N-Desmethylclozapine
T5158
N-Desmethylclozapine (Desmethylclozapine) is an antagonist of serotonin (5-HT) receptor subtype 5-HT2C (IC50: 7.1 nM). It also is an antagonist at dopamine D4 re...
BTRX-335140
T14835
BTRX-335140 (CYM-53093) is a potent and selective, orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC50 value...
BMS-986122
T26869
BMS-986122 (BMS 986122) is a positive allosteric modulator of μ-opioid receptors that increases β-arrestin recruitment stimulated by endomorphin 1 in U2OS-OPRM1 ...
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TargetMol