TN4435 |
Licopyranocoumarin
|
117038-80-9
|
98%
|
|
Licopyranocoumarin could as a potent neuroprotective drug via markedly blocked MPP+-induced neuronal PC12D cell death and disappearance of mitochondrial membrane...
|
TN1526 |
Corydalmine
|
30413-84-4
|
98%
|
|
Corydalmine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains.1-Corydalmine significantly inhibits spor...
|
TQ0276 |
Methysticin
|
20697-20-5
|
98%
|
|
Methysticin, a major kavalactone extracted from kava, can induce CYP1A1.
|
TN3875 |
Dipterocarpol
|
471-69-2
|
98%
|
|
Dipterocarpol is a dammarane-type triterpenoid, as are the major bioactive compounds of ginseng. Dipterocarpol A shows moderate acetylcholinesterase inhibitory a...
|
TN1210 |
2-Hydroxy-1-Methoxyaporphine
|
33770-27-3
|
98%
|
|
2-Hydroxy-1-Methoxyaporphine can inhibit CYP2D6 activity, it also increase the glucose consumption significantly as rosiglitazone.
|
T10535L |
BI 653048 phosphate
|
1198784-97-2
|
98%
|
|
BI 653048 phosphate is a selective and orally active agonist of nonsteroidal glucocorticoid (GC)(IC50 : 55 nM).
|
TN1748 |
Humantenirine
|
82375-30-2
|
98%
|
|
Humantenirine is a natural product of Gelsemium, Loganiaceae. The catalog number is TN1748 and the CAS number is 82375-30-2. Humantenirine can be used as a refer...
|
TN3627 |
Chalepensin
|
13164-03-9
|
98%
|
|
Chalepensin behaves as an energy transfer inhibitor at low concentration, it inhibits multiple P450s and that epoxidation activity is crucial for the potential d...
|
TN3147 |
6',7'-Dihydroxybergamottin
|
264234-05-1
|
98%
|
|
6',7'-Dihydroxybergamottin(DHB), a well-known inhibitor of CYP3A4, the inhibition of CYP3A4 activity by DHB includes the inhibition of POR activity, DHB can inhi...
|
TN3574 |
Canadine
|
5096-57-1
|
98%
|
|
Canadine has antioxidant activity with low-toxic effect.
|
T10688 |
Casopitant mesylate
|
414910-30-8
|
98%
|
|
Casopitant mesylate (GW679769B) is a selective, brain permeable, and orally active antagonist of neurokinin 1 (NK1) receptor. It is a second in the class of anti...
|
TN4130 |
Germacrone 4,5-epoxide
|
92691-35-5
|
98%
|
|
(4S,5S)-(+)-Germacrone-4,5-epoxide inhibits certain subtypes of cytochrome P450 (CYP).
|
T14678 |
BMS-819881
|
1197420-05-5
|
98%
|
|
BMS-819881 is a melaninconcentrating hormone receptor 1 (MCHR1) antagonist, which binds rat MCHR1 with a Ki of 7 nM and it also is selective and potent for CYP3A...
|
T5S0669 |
Bergamottin
|
7380-40-7
|
99.99%
|
|
1. Bergamottin (5-Geranoxypsoralen) can significantly reduce blood glucose and increase glucose tolerance and insulin sensitivity in KK-Aydiabetic mic...
|
T2088 |
APD668
|
832714-46-2
|
99.97%
|
|
APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.
|
T1149 |
Fenofibrate
|
49562-28-9
|
99.97%
|
|
Fenofibrate (Lipanthyl) is a peroxisome proliferator receptor alpha agonist. Fenofibrate is a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyp...
|
T10953 |
Dafadine-A
|
1065506-69-5
|
99.96%
|
|
Dafadine-A is an analog of dafadine and a novel inhibitor of DAF-9 cytochrome P450 in the nematode Caenorhabditis elegans. Mammalian orthologs that also inhibit ...
|
T8937 |
Soticlestat
|
1429505-03-2
|
99.95%
|
|
Soticlestat (OV935) is a potent, selective and orally active cholesterol 24-hydroxylase (CYP46A1) inhibitor. It has the potential for epilepsy syndromes research...
|
T0920 |
Ambroxol
|
18683-91-5
|
99.95%
|
|
Ambroxol (NA-872) is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of...
|
T3158L |
Harman hydrochloride
|
21655-84-5
|
99.95%
|
|
Harman hydrochloride can directly induce CYP1A1 gene expression in an AhR-dependent manner and may represent a novel mechanism by which harman promotes mutagenic...
|