Cat. No. | Product name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
TQ0235 | AC710 | 1351522-04-7 | 98% |
|
AC710 is a potent PDGFR inhibitor (Kds: 0.6, 1, 1.57, 1.3, 1 nM for FLT3, KIT, CSF1R, PDGFRα and PDGFRβ). | ||||
T5001 | Nintedanib esylate | 656247-18-6 | 98% |
|
Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β | ||||
T76761 | Olaratumab | 1024603-93-7 | 98% |
Olaratumab
|
Olaratumab(IMC-3G3) is a human monoclonal IgG1 antibody against platelet-derived growth factor receptor alpha (PDGFRα), which has antitumor effects and can be us... | ||||
T8900 | Seralutinib | 1619931-27-9 | 98% |
|
Seralutinib (GB002) is an inhibitor of inhaled PDGFRα and PDGFRβ. It is used in the study for pulmonary arterial hypertension. | ||||
T16947 | SU16f | 251356-45-3 | 98% |
|
SU16f (3-substituted indolin-2-one 16f) is a potent and selective PDGFRβ inhibitor (IC50s: 10 nM, 140 nM, 2.29 μM for PDGFRβ, PDGFR1, PDGFR2, respectively). Neut... | ||||
T1895 | SKLB 610 | 1125780-41-7 | 98% |
|
SKLB610, a novel multi-targeted inhibitor, inhibits angiogenesis-related tyrosine kinase VEGFR2, FGFR2, and PDGFR at a rate of 97%, 65%, and 55%, respectively, a... | ||||
T0093 | Sorafenib tosylate | 475207-59-1 | 98% |
|
Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf). |