PPAR

In the field of molecular biology, the peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes. PPARs play essential roles in the regulation of cellular differentiation, development, and metabolism (carbohydrate, lipid, protein), and tumorigenesis of higher organisms.

Cat. No.	Product name	CAS No.	Purity
T10044	13-Oxo-9E,11E-octadecadienoic acid	29623-29-8	98%
T10044	13-Oxo-9E,11E-octadecadienoic acid, a potent PPARα activator derived from tomato juice and an isomer of 9-oxo-ODA, exhibits the ability to decrease plasma and he...
TN3655	Cimiside E	154822-57-8	98%
TN3655	Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2,...
T14948	Chiglitazar	743438-45-1	98%
T14948	Chiglitazar is a dual agonist of PPARα/γ (EC50s: 1.2, 0.08, and 1.7 μM for PPARα, PPARγ, and PPARδ).
T1149	Fenofibrate	49562-28-9	99.97%
T1149	Fenofibrate (Lipanthyl) is a peroxisome proliferator receptor alpha agonist. Fenofibrate is a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyp...
T24827	SR 16832	2088135-12-8	99.96%
T24827	SR 16832 is a dual-site PPARγ inhibitor. It also inhibits the binding of endogenous ligands and transcriptional activity of PPARγ, more effectively than the orth...
T2396	Ramatroban	116649-85-5	99.96%
T2396	Ramatroban (BAY u3405) (BAY u3405) is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis. It has been used in trials studying the treatment of...
TN1018	Angeloylgomisin H	66056-22-2	99.95%
TN1018	Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines.
T1264	Ciprofibrate	52214-84-3	99.95%
T1264	Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.
T3941	Choline Fenofibrate	856676-23-8	99.95%
T3941	Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity...
T1402	Fenofibric acid	42017-89-0	99.94%
T1402	Fenofibric acid (FNF acid) is the active form of fenofibrate, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity.
T6151	GW 501516	317318-70-0	99.94%
T6151	GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.
T2260	GW9662	22978-25-2	99.94%
T2260	GW9662 (TIMTEC-BB SBB006523) is a specific PPARγ antagonist (IC50: 3.3 nM, in a cell-free assay), with 100 to 1000-fold functional selectivity for PPARγ than PPA...
T3917	Protopanaxatriol	1453-93-6	99.92%
T3917	Protopanaxatriol (20(R)-APPT), a major ginseng constituent, is a novel PPARγ antagonist.
T13803	N-Oleoyl glycine	2601-90-3	99.92%
T13803	N-Oleoyl Glycine, a Lipoamino Acid, Stimulates Adipogenesis Associated With Activation of CB1 Receptor and Akt Signaling Pathway in 3T3-L1 Adipocyte
TQ0107	Pemafibrate	848259-27-8	99.91%
TQ0107	Pemafibrate ((R)-K-13675) is a highly specific PPARα agonist (EC50: 1 nM).
T1415	Gemfibrozil	25812-30-0	99.9%
T1415	Gemfibrozil (CI-719) interacts with peroxisome proliferator-activated receptors (PPARalpha) resulting in PPARalpha-mediated stimulation of fatty acid oxidation a...
T2674	GSK0660	1014691-61-2	99.9%
T2674	GSK0660 is an antagonist and inverse agonist of PPARβ/δ.
T15453	GW7647	265129-71-3	99.89%
T15453	GW7647 is a potent agonist of PPARα (EC50s: 6 nM, 1.1 μM, and 6.2 μM for human PPARα, PPARγ, and PPARδ, respectively).
T8374	LJ570	2252488-69-8	99.89%
T8374	LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)
T4S1173	Agrimol B	55576-66-4	99.89%
T4S1173	1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.