T0061 |
Clofibric acid
|
882-09-7
|
99.68%
|
|
Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE.
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T1088 |
Repaglinide
|
135062-02-1
|
99.66%
|
|
Repaglinide (AG-EE 623ZW) is a benzoic acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Repagli...
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T0214L |
Pioglitazone hydrochloride
|
112529-15-4
|
99.66%
|
|
Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic ac...
|
TN5137 |
Tetramethylkaempferol
|
16692-52-7
|
99.65%
|
|
Tetramethylkaempferol is a PPARγ agonist, it can improve insulin sensitivity by increasing the levels of adiponectin, an important adipocytokine associated with ...
|
T68000L |
MK-0533
|
668455-28-5
|
99.64%
|
|
MK-0533 is a novel PPARγ partial agonist for the prevention of vascular endothelial dysfunction (VED) and VED-related cardiovascular disease.
|
T10783 |
CGS 15435
|
95853-92-2
|
99.63%
|
|
CGS 15435 is a potent thromboxen (TxA2) synthetase inhibitor (IC50: 1 nM). CGS 15435 acts on PGI2 synthase, cyclooxygenase and liposynthase with much less select...
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T16022 |
Arhalofenate
|
24136-23-0
|
99.62%
|
|
Arhalofenate (JNJ 39659100) is a selective partial agonist of peroxisome proliferator-activated receptor PPARγ. It is used for the treatment of type 2 diabetes.
|
T5764 |
Alliin
|
556-27-4
|
99.62%
|
|
Alliin ((S)-3-(Allylsulphinyl)-L-alanine) is a garlic organosulfur compound that possesses various pharmacological properties.alliin protected against LPS-induce...
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T3867 |
Alpinetin
|
36052-37-6
|
99.61%
|
|
Alpinetin ((-)-alpinetin) has antibacterial activity.Alpinetin has anti-inflammatory activity.Alpinetin can enhance the sensitivity of HepG2 hepatoma cells to th...
|
T11747 |
KD-3010
|
934760-92-6
|
99.61%
|
|
KD-3010 (Kalypsys) is an orally active potent and selective PPARδ agonist for the study of liver injury.
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T0705 |
Triflusal
|
322-79-2
|
99.61%
|
|
Triflusal (UR1501) is a 2-acetoxy-4-trifluoromethylbenzoic acid and it is an aspirin chemically-related molecule but not a derivative.
|
T60184 |
TUG-499
|
1206629-08-4
|
99.59%
|
|
TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) agonist (EC50: 7.39).TUG-499 has an affinity for FFAR1 or GPR40 over the related receptors FFA...
|
T15581 |
Inolitazone
|
223132-37-4
|
99.58%
|
|
Inolitazone (RS5444) a high-affinity PPARγ agonist. Inolitazone exhibits IC50 for growth inhibition is ~0.8 nM in vitro.
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T0214 |
Pioglitazone
|
111025-46-8
|
99.57%
|
|
Pioglitazone (U 72107) is an insulin sensitizing agent and thiazolidinedione that is indicated for the treatment of type 2 diabetes. Pioglitazone has been linked...
|
TN3500 |
Beta-Amyrone
|
638-97-1
|
99.55%
|
|
beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through ...
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T4408 |
Elafibranor
|
923978-27-2
|
99.55%
|
|
Elafibranor (GFT505) is an agonist of the peroxisome proliferator-activated receptor-α (PPAR-α) and peroxisome proliferator-activated receptor-δ (PPAR-δ) with EC...
|
T0212 |
Seratrodast
|
112665-43-7
|
99.54%
|
|
Seratrodast (ABT-001) (INN), a thromboxane A2 (TXA2) receptor (TP receptor) antagonist, is mainly used in the therapy of asthma. It was the first TP receptor ant...
|
T1051 |
Retinoic acid
|
302-79-4
|
99.52%
|
|
Retinoic acid (Tretinoin), a metabolite of vitamin A, is a natural agonist of the retinoic acid receptor RAR and inhibits RARα/β/γ (IC50=14 nM). Retinoic acid in...
|
T2413 |
FH535
|
108409-83-2
|
99.5%
|
|
FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.
|
T15049 |
Daltroban
|
79094-20-5
|
99.49%
|
|
Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist. Daltroban shows protective effect in reperfusion injury. Daltroban increase intrac...
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